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Select item 109477691.

Double Knockout of Carbonic Anhydrase II (CAII) and Na⁺-Cl⁻ Cotransporter (NCC) Causes Salt Wasting and Volume Depletion

Jie Xu, Sharon Barone, Mary-Beth Brooks, Manoocher Soleimani

Cell Physiol Biochem. Author manuscript; available in PMC 2024 Mar 18.

Published in final edited form as: Cell Physiol Biochem. 2013; 32(7): 173–183. Published online 2013 Dec 18. doi: 10.1159/000356637

PMCID:: PMC10947769

Abstract Article PDF–868K

Select item 109477512.

Ablation of the Cl⁻/HCO₃⁻ Exchanger Pendrin Enhances Hydrochlorothiazide-Induced Diuresis

Saeed Alshahrani, Manoocher Soleimani

Kidney Blood Press Res. Author manuscript; available in PMC 2024 Mar 18.

Published in final edited form as: Kidney Blood Press Res. 2017; 42(3): 444–455. Published online 2017 Jul 27. doi: 10.1159/000479296

PMCID:: PMC10947751

Abstract Article PDF–1.2M

Select item 105064133.

Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development

Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin-Xian Xu

Front Cell Dev Biol. 2023; 11: 1233317. Published online 2023 Sep 4. doi: 10.3389/fcell.2023.1233317

PMCID:: PMC10506413

Abstract Article PDF–7.2M

Select item 104113844.

Multiple molecular mechanisms are involved in the activation of the kidney sodium-chloride cotransporter by hypokalemia

Adrián R. Murillo-de-Ozores, Héctor Carbajal-Contreras, Germán R. Magaña-Ávila, Raquel Valdés, Leoneli I. Grajeda-Medina, Norma Vázquez, Teresa Zariñán, Alejandro López-Saavedra, Avika Sharma, Dao-Hong Lin, Wen-Hui Wang, Eric Delpire, David H. Ellison, Gerardo Gamba, María Castañeda-Bueno

Kidney Int. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: Kidney Int. 2022 Nov; 102(5): 1030–1041. Published online 2022 Jul 21. doi: 10.1016/j.kint.2022.06.027

PMCID:: PMC10411384

Abstract Article PDF–3.6M

Select item 101032625.

Tet2- and Tet3-Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment

Xiujie Liang, Tamas Aranyi, Jianfu Zhou, Yuting Guan, Hailong Hu, Hongbo Liu, Katalin Susztak

J Am Soc Nephrol. 2023 Apr; 34(4): 572–589. Published online 2022 Dec 15. doi: 10.1681/ASN.2022040460

PMCID:: PMC10103262

Abstract Article

Select item 97323256.

Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulation

Xian Zhang, Songyuan Luo, Minjie Wang, Qiongqiong Cao, Zhixin Zhang, Qin Huang, Jie Li, Zhiyong Deng, Tianxiao Liu, Cong-Lin Liu, Mathilde Meppen, Amelie Vromman, Richard A. Flavell, Gökhan S. Hotamışlıgil, Jian Liu, Peter Libby, Zhangsuo Liu, Guo-Ping Shi

Nat Commun. 2022; 13: 7582. Published online 2022 Dec 8. doi: 10.1038/s41467-022-35256-8

PMCID:: PMC9732325

Abstract Article PDF–8.5M

Select item 93828997.

Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney

Mary Taglienti, Daniel Graf, Valerie Schumacher, Jordan A. Kreidberg

Development. 2022 Jul 15; 149(14): dev200773. Published online 2022 Jul 25. doi: 10.1242/dev.200773

PMCID:: PMC9382899

Abstract Article

Select item 92329758.

Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency

Nan Guan, Hanako Kobayashi, Ken Ishii, Olena Davidoff, Feng Sha, Talat A. Ikizler, Chuan-Ming Hao, Navdeep S. Chandel, Volker H. Haase

Kidney Int. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Kidney Int. 2022 Jul; 102(1): 108–120. Published online 2022 Mar 24. doi: 10.1016/j.kint.2022.02.030

PMCID:: PMC9232975

Abstract Article PDF–1.7M

Select item 85649139.

Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency

Meng-Hsuan Lin, Jen-Chi Chen, Xuejiao Tian, Chia-Ming Lee, I-Shing Yu, Yi-Fen Lo, Shinichi Uchida, Chou-Long Huang, Bi-Chang Chen, Chih-Jen Cheng

JCI Insight. 2021 Oct 22; 6(20): e151039. Published online 2021 Oct 22. doi: 10.1172/jci.insight.151039

PMCID:: PMC8564913

Abstract Article PDF–6.6M

Select item 831890110.

High dietary potassium causes ubiquitin-dependent degradation of the kidney sodium-chloride cotransporter

Marleen L.A. Kortenoeven, Cristina Esteva-Font, Henrik Dimke, Søren B. Poulsen, Sathish K. Murali, Robert A. Fenton

J Biol Chem. 2021 Aug; 297(2): 100915. Published online 2021 Jun 24. doi: 10.1016/j.jbc.2021.100915

PMCID:: PMC8318901

Abstract Article PDF–3.1M

Select item 812647911.

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model

Leticia L. Niborski, Mélanie Paces-Fessy, Pierbruno Ricci, Adeline Bourgeois, Pedro Magalhães, Maria Kuzma-Kuzniarska, Celine Lesaulnier, Martin Reczko, Edwige Declercq, Petra Zürbig, Alain Doucet, Muriel Umbhauer, Silvia Cereghini

Dis Model Mech. 2021 May 1; 14(5): dmm047498. Published online 2021 May 4. doi: 10.1242/dmm.047498

PMCID:: PMC8126479

Abstract Article

Select item 805025212.

Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects

Gijs A. C. Franken, Murat Seker, Caro Bos, Laura A. H. Siemons, Bram C. J. van der Eerden, Annabel Christ, Joost G. J. Hoenderop, René J. M. Bindels, Dominik Müller, Tilman Breiderhoff, Jeroen H. F. de Baaij

Sci Rep. 2021; 11: 8217. Published online 2021 Apr 15. doi: 10.1038/s41598-021-87548-6

PMCID:: PMC8050252

Abstract Article PDF–1.5M

Select item 752001413.

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation

Jeannine M. Basta, Ajeet P. Singh, Lynn Robbins, Lisa Stout, Michelle Pherson, Michael Rauchman

Dev Biol. Author manuscript; available in PMC 2020 Sep 27.

Published in final edited form as: Dev Biol. 2020 Aug 15; 464(2): 176–187. Published online 2020 Jun 3. doi: 10.1016/j.ydbio.2020.05.008

PMCID:: PMC7520014

Abstract Article PDF–2.6M

Select item 726934514.

Renal Tubule Nedd4-2 Deficiency Stimulates Kir4.1/Kir5.1 and Thiazide-Sensitive NaCl Cotransporter in Distal Convoluted Tubule

Peng Wu, Xiao-Tong Su, Zhong-Xiuzi Gao, Dan-Dan Zhang, Xin-Peng Duan, Yu Xiao, Olivier Staub, Wen-Hui Wang, Dao-Hong Lin

J Am Soc Nephrol. 2020 Jun; 31(6): 1226–1242. Published online 2020 Apr 15. doi: 10.1681/ASN.2019090923

PMCID:: PMC7269345

Abstract Article

Select item 682881515.

β-catenin regulates the formation of multiple nephron segments in the mouse kidney

Patrick Deacon, Charles W. Concodora, Eunah Chung, Joo-Seop Park

Sci Rep. 2019; 9: 15915. Published online 2019 Nov 4. doi: 10.1038/s41598-019-52255-w

PMCID:: PMC6828815

Abstract Article PDF–3.3M

Select item 668370616.

Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter

Lei Cheng, Søren Brandt Poulsen, Qi Wu, Cristina Esteva-Font, Emma T. B. Olesen, Li Peng, Björn Olde, L. M. Fredrik Leeb-Lundberg, Trairak Pisitkun, Timo Rieg, Henrik Dimke, Robert A. Fenton

J Am Soc Nephrol. 2019 Aug; 30(8): 1454–1470. Published online 2019 Jun 28. doi: 10.1681/ASN.2018101025

PMCID:: PMC6683706

Abstract Article

Select item 648117717.

Potassium (K⁺) intake modulates NCC activity via the K⁺ channel, Kir4.1

Ming-Xiao Wang, Catherina Cuevas Gallardo, Xiao-Tong Su, Peng Wu, Zhong-Xiuzi Gao, Dao-Hong Lin, James A. McCormick, Chao-Ling Yang, Wen-Hui Wang, David H. Ellison

Kidney Int. Author manuscript; available in PMC 2019 Apr 24.

Published in final edited form as: Kidney Int. 2018 Apr; 93(4): 893–902. Published online 2018 Jan 6. doi: 10.1016/j.kint.2017.10.023

PMCID:: PMC6481177

Abstract Article PDF–1.6M

Select item 617257018.

H⁺-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney

Sebastian Frische, Régine Chambrey, Francesco Trepiccione, Reza Zamani, Niels Marcussen, R. Todd Alexander, Karsten Skjødt, Per Svenningsen, Henrik Dimke

Am J Physiol Renal Physiol. 2018 Sep 1; 315(3): F429–F444. Published online 2018 Jul 11. doi: 10.1152/ajprenal.00539.2017

PMCID:: PMC6172570

Abstract Article

Select item 612441519.

Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome

Sierra S. Marable, Eunah Chung, Mike Adam, S. Steven Potter, Joo-Seop Park

JCI Insight. 2018 Jul 26; 3(14): e97497. Published online 2018 Jul 25. doi: 10.1172/jci.insight.97497

PMCID:: PMC6124415

Abstract Article PDF–1.2M

Select item 603191120.

Differential roles of WNK4 in regulation of NCC in vivo

Yih-Sheng Yang, Jian Xie, Sung-Sen Yang, Shih-Hua Lin, Chou-Long Huang

Am J Physiol Renal Physiol. 2018 May 1; 314(5): F999–F1007. Published online 2018 Jan 31. doi: 10.1152/ajprenal.00177.2017

PMCID:: PMC6031911

Abstract Article

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