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Items: 1 to 20 of 28

1.
The helicase-like transcription factor (HLTF) in cancer: loss of function or oncomorphic conversion of a tumor suppressor?
Ludovic Dhont, Céline Mascaux, Alexandra Belayew
Cell Mol Life Sci. 2016 Jan; 73(1): 129–145. Published online 2015 Oct 15. doi: 10.1007/s00018-015-2060-6
PMCID:
PMC11108516
AbstractArticlePDF–970K
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality
Gurvinder Kaur, Rebecca A. Helmer, Dalia Martinez-Marin, Souad R. Sennoune, Rachel L. Washburn, Raul Martinez-Zaguilan, Jannette M. Dufour, Beverly S. Chilton
PLoS One. 2023; 18(8): e0286109. Published online 2023 Aug 25. doi: 10.1371/journal.pone.0286109
PMCID:
PMC10456192
AbstractArticlePDF–3.7M
4.
The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity
Jun Li, Chunming Cheng, Jinshu Xu, Ting Zhang, Bengu Tokat, Georgia Dolios, Aarthi Ramakrishnan, Li Shen, Rong Wang, Pin-Xian Xu
Nucleic Acids Res. 2022 Oct 14; 50(18): 10343–10359. Published online 2022 Sep 21. doi: 10.1093/nar/gkac760
PMCID:
PMC9561260
AbstractArticlePDF–9.9M
5.
Activation of the p11/SMARCA3/Neurensin-2 pathway in parvalbumin interneurons mediates the response to chronic antidepressants
Gali Umschweif, Lucian Medrihan, Kathryn A. McCabe, Yotam Sagi, Paul Greengard
Mol Psychiatry. 2021; 26(7): 3350–3362. Published online 2021 Mar 15. doi: 10.1038/s41380-021-01059-4
PMCID:
PMC8505248
AbstractArticlePDF–2.1M
6.
Helicase-like transcription factor-deletion from the tumor microenvironment in a cell line-derived xenograft model of colorectal cancer reprogrammed the human transcriptome-S-nitroso-proteome to promote inflammation and redirect metastasis
Rebecca A. Helmer, Raul Martinez-Zaguilan, Gurvinder Kaur, Lisa A. Smith, Jannette M. Dufour, Beverly S. Chilton
PLoS One. 2021; 16(5): e0251132. Published online 2021 May 19. doi: 10.1371/journal.pone.0251132
PMCID:
PMC8133447
AbstractArticlePDF–4.3M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Helicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice
Rebecca A. Helmer, Gurvinder Kaur, Lisa A. Smith, Beverly S. Chilton
PLoS One. 2019; 14(8): e0221751. Published online 2019 Aug 28. doi: 10.1371/journal.pone.0221751
PMCID:
PMC6713344
AbstractArticlePDF–2.6M
9.
Alternative splicing of helicase-like transcription factor (Hltf): Intron retention-dependent activation of immune tolerance at the feto-maternal interface
Gurvinder Kaur, Rebecca A. Helmer, Lisa A. Smith, Raul Martinez-Zaguilan, Jannette M. Dufour, Beverly S. Chilton
PLoS One. 2018; 13(7): e0200211. Published online 2018 Jul 5. doi: 10.1371/journal.pone.0200211
PMCID:
PMC6033450
AbstractArticlePDF–17M
10.
Genomic variants in an inbred mouse model predict mania-like behaviors
Michael C. Saul, Sharon A. Stevenson, Changjiu Zhao, Terri M. Driessen, Brian E. Eisinger, Stephen C. Gammie
PLoS One. 2018; 13(5): e0197624. Published online 2018 May 16. doi: 10.1371/journal.pone.0197624
PMCID:
PMC5955540
AbstractArticlePDF–3.1M
11.
Structure of a Novel DNA-binding Domain of Helicase-like Transcription Factor (HLTF) and Its Functional Implication in DNA Damage Tolerance
Asami Hishiki, Kodai Hara, Yuzu Ikegaya, Hideshi Yokoyama, Toshiyuki Shimizu, Mamoru Sato, Hiroshi Hashimoto
J Biol Chem. 2015 May 22; 290(21): 13215–13223. Published online 2015 Apr 9. doi: 10.1074/jbc.M115.643643
PMCID:
PMC4505575
AbstractArticlePDF–2.2M
12.
DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis
Michelle K. Zeman, Jia-Ren Lin, Raimundo Freire, Karlene A. Cimprich
J Cell Biol. 2014 Jul 21; 206(2): 183–197. doi: 10.1083/jcb.201311063
PMCID:
PMC4107794
AbstractArticlePDF–3.2M
13.
Helicase-Like Transcription Factor (Hltf) Regulates G2/M Transition, Wt1/Gata4/Hif-1a Cardiac Transcription Networks, and Collagen Biogenesis
Rebecca A. Helmer, Raul Martínez-Zaguilán, Janet S. Dertien, Candra Fulford, Oded Foreman, Vasum Peiris, Beverly S. Chilton
PLoS One. 2013; 8(11): e80461. Published online 2013 Nov 20. doi: 10.1371/journal.pone.0080461
PMCID:
PMC3835564
AbstractArticlePDF–4.9M
14.
Role of Helicase-Like Transcription Factor (Hltf) in the G2/M Transition and Apoptosis in Brain
Rebecca A. Helmer, Oded Foreman, Janet S. Dertien, Marlyn Panchoo, Suhani M. Bhakta, Beverly S Chilton
PLoS One. 2013; 8(6): e66799. Published online 2013 Jun 24. doi: 10.1371/journal.pone.0066799
PMCID:
PMC3691323
AbstractArticlePDF–3.1M
15.
SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action
Yong-Seok Oh, Pu Gao, Ko-Woon Lee, Ilaria Ceglia, Ji-Seon Seo, Xiaozhu Zhang, Jung-Hyuck Ahn, Brian T. Chait, Dinshaw J. Patel, Yong Kim, Paul Greengard
Cell. Author manuscript; available in PMC 2014 Feb 14.
Published in final edited form as: Cell. 2013 Feb 14; 152(4): 831–843. doi: 10.1016/j.cell.2013.01.014
PMCID:
PMC3633087
AbstractArticlePDF–3.0M
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: Existence of an alternative E3 ligase
Peter H.L. Krijger, Kyoo-Young Lee, Niek Wit, Paul C.M. van den Berka, Xiaoli Wu, Henk P. Roest, Alex Maas, Hao Ding, Jan H.J. Hoeijmakers, Kyungjae Myung, Heinz Jacobs
DNA Repair (Amst) Author manuscript; available in PMC 2012 Jun 25.
Published in final edited form as: DNA Repair (Amst). 2011 Apr 3; 10(4): 438–444. Published online 2011 Jan 26. doi: 10.1016/j.dnarep.2010.12.008
PMCID:
PMC3381732
AbstractArticlePDF–1.0M
18.
Loss of HLTF function promotes intestinal carcinogenesis
Sumit Sandhu, Xiaoli Wu, Zinnatun Nabi, Mojgan Rastegar, Sam Kung, Sabine Mai, Hao Ding
Mol Cancer. 2012; 11: 18. Published online 2012 Mar 27. doi: 10.1186/1476-4598-11-18
PMCID:
PMC3337324
AbstractArticlePDF–12M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58
Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara
Dev Cell. Author manuscript; available in PMC 2011 Jun 7.
Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011
PMCID:
PMC3110151
AbstractArticlePDF–2.0M

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