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Select item 91197361.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73063623.

Analysis of TATA-box binding protein associated factor 4b gene mutations in a Chinese population with nonobstructive azoospermia

Qi Xi, Hao Zhang, Xinyue Zhang, Yuting Jiang, Ruixue Wang, Ruizhi Liu, Hongguo Zhang

Medicine (Baltimore) 2020 Jun 5; 99(23): e20561. Published online 2020 Jun 5. doi: 10.1097/MD.0000000000020561

PMCID:: PMC7306362

Abstract Article PDF–1.0M

Select item 69420444.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 67632425.

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development

Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong

J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107

PMCID:: PMC6763242

Abstract Article PDF–12M

Select item 66917506.

Targeted Next-Generation Sequencing Identifies Novel Sequence Variations of Genes Associated with Nonobstructive Azoospermia in the Han Population of Northeast China

Xiangyin Liu, Qi Xi, Leilei Li, Qiyuan Wang, Yuting Jiang, Hongguo Zhang, Ruizhi Liu, Ruixue Wang

Med Sci Monit. 2019; 25: 5801–5812. Published online 2019 Aug 4. doi: 10.12659/MSM.915375

PMCID:: PMC6691750

Abstract Article PDF–1.2M

Select item 58269267.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 56902828.

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID

Kapil Gupta, Aleksandra A Watson, Tiago Baptista, Elisabeth Scheer, Anna L Chambers, Christine Koehler, Juan Zou, Ima Obong-Ebong, Eaazhisai Kandiah, Arturo Temblador, Adam Round, Eric Forest, Petr Man, Christoph Bieniossek, Ernest D Laue, Edward A Lemke, Juri Rappsilber, Carol V Robinson, Didier Devys, Làszlò Tora, Imre Berger

eLife. 2017; 6: e30395. Published online 2017 Nov 7. doi: 10.7554/eLife.30395

PMCID:: PMC5690282

Abstract Article PDF–4.0M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 492039410.

TAF4b Regulates Oocyte-Specific Genes Essential for Meiosis

Kathryn J. Grive, Eric A. Gustafson, Kimberly A. Seymour, Melody Baddoo, Christoph Schorl, Kayla Golnoski, Aleksandar Rajkovic, Alexander S. Brodsky, Richard N. Freiman

PLoS Genet. 2016 Jun; 12(6): e1006128. Published online 2016 Jun 24. doi: 10.1371/journal.pgen.1006128

PMCID:: PMC4920394

Abstract Article PDF–5.3M

Select item 461721111.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 394919612.

Targeting TBP-Associated Factors in Ovarian Cancer

Jennifer R. Ribeiro, Lindsay A. Lovasco, Barbara C. Vanderhyden, Richard N. Freiman

Front Oncol. 2014; 4: 45. Published online 2014 Mar 11. doi: 10.3389/fonc.2014.00045

PMCID:: PMC3949196

Abstract Article PDF–1.9M

Select item 360788613.

A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis

Nicolas Greliche, Marine Germain, Jean-Charles Lambert, William Cohen, Marion Bertrand, Anne-Marie Dupuis, Luc Letenneur, Mark Lathrop, Philippe Amouyel, Pierre-Emmanuel Morange, David-Alexandre Trégouët

BMC Med Genet. 2013; 14: 36. Published online 2013 Mar 20. doi: 10.1186/1471-2350-14-36

PMCID:: PMC3607886

Abstract Article PDF–191K

Select item 334973414.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695

PMCID:: PMC3349734

Abstract Article PDF–377K

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 314532516.

Human Mediator Subunit Med26 Functions As A Docking Site For Transcription Elongation Factors

Hidehisa Takahashi, Tari J. Parmely, Shigeo Sato, Chieri Tomomori-Sato, Charles A. S. Banks, Stephanie E. Kong, Henrietta Szutorisz, Selene K. Swanson, Skylar Martin-Brown, Michael P. Washburn, Laurence Florens, Chris Seidel, Chengqi Lin, Edwin R. Smith, Ali Shilatifard, Ronald C. Conaway, Joan W. Conaway

Cell. Author manuscript; available in PMC 2012 Jul 8.

Published in final edited form as: Cell. 2011 Jul 8; 146(1): 92–104. doi: 10.1016/j.cell.2011.06.005

PMCID:: PMC3145325

Abstract Article PDF–1.9M

Select item 278531617.

TAF4/4b·TAF12 Displays a Unique Mode of DNA Binding and Is Required for Core Promoter Function of a Subset of Genes

Kfir Gazit, Sandra Moshonov, Rofa Elfakess, Michal Sharon, Gabrielle Mengus, Irwin Davidson, Rivka Dikstein

J Biol Chem. 2009 Sep 25; 284(39): 26286–26296. Published online 2009 Jul 27. doi: 10.1074/jbc.M109.011486

PMCID:: PMC2785316

Abstract Article PDF–2.0M

Select item 248683518.

Structural changes in TAF4b-TFIID correlate with promoter selectivity

Wei-Li Liu, Robert A. Coleman, Patricia Grob, David S. King, Laurence Florens, Michael P. Washburn, Kenneth G. Geles, Joyce L. Yang, Vincent Ramey, Eva Nogales, Robert Tjian

Mol Cell. Author manuscript; available in PMC 2008 Jul 28.

Published in final edited form as: Mol Cell. 2008 Jan 18; 29(1): 81–91. doi: 10.1016/j.molcel.2007.11.003

PMCID:: PMC2486835

Abstract Article PDF–7.4M

Select item 117084419.

TAFII105 mediates activation of anti-apoptotic genes by NF-kappaB.

A Yamit-Hezi, R Dikstein

EMBO J. 1998 Sep 1; 17(17): 5161–5169. doi: 10.1093/emboj/17.17.5161

PMCID:: PMC1170844

Summary PDF–455K

Select item 117034620.

Three transitions in the RNA polymerase II transcription complex during initiation.

F C Holstege, U Fiedler, H T Timmers

EMBO J. 1997 Dec 15; 16(24): 7468–7480. doi: 10.1093/emboj/16.24.7468

PMCID:: PMC1170346

Summary PDF–609K

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