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Select item 113308661.

Ribosome stalling during c-myc translation presents actionable cancer cell vulnerability

Tejinder Pal Khaket, Suman Rimal, Xingjun Wang, Sunil Bhurtel, Yen-Chi Wu, Bingwei Lu

PNAS Nexus. 2024 Aug; 3(8): pgae321. Published online 2024 Aug 13. doi: 10.1093/pnasnexus/pgae321

Correction in:: PNAS Nexus. 2024 Nov; 3(11): pgae478.

PMCID:: PMC11330866

Abstract Article PDF–1015K

Select item 110445052.

Dysregulation of innate immune signaling in animal models of spinal muscular atrophy

Eric L. Garcia, Rebecca E. Steiner, Amanda C. Raimer, Laura E. Herring, A. Gregory Matera, Ashlyn M. Spring

BMC Biol. 2024; 22: 94. Published online 2024 Apr 25. doi: 10.1186/s12915-024-01888-z

PMCID:: PMC11044505

Abstract Article PDF–4.0M

Select item 101057363.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 98832054.

Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration

Yasufumi Sakakibara, Risa Yamashiro, Sachie Chikamatsu, Yu Hirota, Yoko Tsubokawa, Risa Nishijima, Kimi Takei, Michiko Sekiya, Koichi M. Iijima

iScience. 2023 Feb 17; 26(2): 105968. Published online 2023 Jan 13. doi: 10.1016/j.isci.2023.105968

PMCID:: PMC9883205

Abstract Article PDF–5.1M

Select item 96376345.

The sooner, the better: ROS, kinases and nutrients at the onset of the damage response in Drosophila

Florenci Serras

Front Cell Dev Biol. 2022; 10: 1047823. Published online 2022 Oct 24. doi: 10.3389/fcell.2022.1047823

PMCID:: PMC9637634

Abstract Article PDF–981K

Select item 90438536.

Phagocytosis Is the Sole Arm of Drosophila melanogaster Known Host Defenses That Provides Some Protection Against Microsporidia Infection

Gaëtan Caravello, Adrien Franchet, Sebastian Niehus, Dominique Ferrandon

Front Immunol. 2022; 13: 858360. Published online 2022 Apr 13. doi: 10.3389/fimmu.2022.858360

PMCID:: PMC9043853

Abstract Article PDF–5.5M

Select item 88566197.

Physiological ROS controls Upd3-dependent modeling of ECM to support cardiac function in Drosophila

Jayati Gera, Prerna Budakoti, Meghna Suhag, Lolitika Mandal, Sudip Mandal

Sci Adv. 2022 Feb; 8(7): eabj4991. Published online 2022 Feb 18. doi: 10.1126/sciadv.abj4991

PMCID:: PMC8856619

Abstract Article PDF–16M

Select item 88056488.

Insect Gut Regeneration

Peng Zhang, Bruce A. Edgar

Cold Spring Harb Perspect Biol. 2022 Feb; 14(2): a040915. doi: 10.1101/cshperspect.a040915

PMCID:: PMC8805648

Abstract Article PDF–1.8M

Select item 86644559.

Functional requirements of protein kinases and phosphatases in the development of the Drosophila melanogaster wing

Cristina M Ostalé, Nuria Esteban, Ana López-Varea, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab348. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab348

PMCID:: PMC8664455

Abstract Article PDF–2.9M

Select item 859010210.

Drosophila p38 MAPK interacts with BAG‐3/starvin to regulate age‐dependent protein homeostasis

Sarah M. Ryan, Michael Almassey, Amelia M. Burch, Gia Ngo, Julia M. Martin, David Myers, Devin Compton, Shira Archie, Megan Cross, Lauren Naeger, Ashley Salzman, Alyssa Virola‐Iarussi, Scott A. Barbee, Nathan T. Mortimer, Subhabrata Sanyal, Alysia D. Vrailas‐Mortimer

Aging Cell. 2021 Nov; 20(11): e13481. Published online 2021 Oct 21. doi: 10.1111/acel.13481

PMCID:: PMC8590102

Abstract Article PDF–2.4M

Select item 837754411.

Physiological Signaling Functions of Reactive Oxygen Species in Stem Cells: From Flies to Man

Sergey A. Sinenko, Tatiana Yu. Starkova, Andrey A. Kuzmin, Alexey N. Tomilin

Front Cell Dev Biol. 2021; 9: 714370. Published online 2021 Aug 6. doi: 10.3389/fcell.2021.714370

PMCID:: PMC8377544

Abstract Article PDF–5.3M

Select item 814263812.

The epigenetic regulator G9a attenuates stress-induced resistance and metabolic transcriptional programs across different stressors and species

Human Riahi, Michaela Fenckova, Kayla J. Goruk, Annette Schenck, Jamie M. Kramer

BMC Biol. 2021; 19: 112. Published online 2021 May 24. doi: 10.1186/s12915-021-01025-0

PMCID:: PMC8142638

Abstract Article PDF–5.3M

Select item 812071313.

Functional conservation in genes and pathways linking ageing and immunity

Daniel K. Fabian, Matías Fuentealba, Handan Melike Dönertaş, Linda Partridge, Janet M. Thornton

Immun Ageing. 2021; 18: 23. Published online 2021 May 14. doi: 10.1186/s12979-021-00232-1

PMCID:: PMC8120713

Abstract Article PDF–2.7M

Select item 811827014.

RACK1 modulates polyglutamine-induced neurodegeneration by promoting ERK degradation in Drosophila

Jun Xie, Yongchao Han, Tao Wang

PLoS Genet. 2021 May; 17(5): e1009558. Published online 2021 May 13. doi: 10.1371/journal.pgen.1009558

PMCID:: PMC8118270

Abstract Article PDF–4.7M

Select item 807915015.

Methionine restriction breaks obligatory coupling of cell proliferation and death by an oncogene Src in Drosophila

Hiroshi Nishida, Morihiro Okada, Lynna Yang, Tomomi Takano, Sho Tabata, Tomoyoshi Soga, Diana M Ho, Jongkyeong Chung, Yasuhiro Minami, Sa Kan Yoo

eLife. 2021; 10: e59809. Published online 2021 Apr 27. doi: 10.7554/eLife.59809

PMCID:: PMC8079150

Abstract Article PDF–6.6M

Select item 787415916.

FOXO Regulates Neuromuscular Junction Homeostasis During Drosophila Aging

Allison Birnbaum, Maggie Sodders, Mark Bouska, Kai Chang, Ping Kang, Elizabeth McNeill, Hua Bai

Front Aging Neurosci. 2020; 12: 567861. Published online 2021 Jan 27. doi: 10.3389/fnagi.2020.567861

PMCID:: PMC7874159

Abstract Article PDF–2.3M

Select item 783109017.

Amyotrophic Lateral Sclerosis Genes in Drosophila melanogaster

Sophie Layalle, Laetitia They, Sarah Ourghani, Cédric Raoul, Laurent Soustelle

Int J Mol Sci. 2021 Jan; 22(2): 904. Published online 2021 Jan 18. doi: 10.3390/ijms22020904

PMCID:: PMC7831090

Abstract Article PDF–3.9M

Select item 755019218.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 739140519.

Evolutionarily conserved transcription factors drive the oxidative stress response in Drosophila

Sarah M. Ryan, Kaitie Wildman, Briseida Oceguera-Perez, Scott Barbee, Nathan T. Mortimer, Alysia D. Vrailas-Mortimer

J Exp Biol. 2020 Jul 15; 223(14): jeb221622. Published online 2020 Jul 20. doi: 10.1242/jeb.221622

PMCID:: PMC7391405

Abstract Article

Select item 733389020.

Genomic instability and cancer: lessons from Drosophila

Stephan U. Gerlach, Héctor Herranz

Open Biol. 2020 Jun; 10(6): 200060. Published online 2020 Jun 3. doi: 10.1098/rsob.200060

PMCID:: PMC7333890

Abstract Article PDF–1.0M

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