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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109083552.

Fat mass and obesity associated protein inhibits neuronal ferroptosis via the FYN/Drp1 axis and alleviate cerebral ischemia/reperfusion injury

Yi Zhang, Xin Gong

CNS Neurosci Ther. 2024 Mar; 30(3): e14636. Published online 2024 Mar 2. doi: 10.1111/cns.14636

PMCID:: PMC10908355

Abstract Article PDF–35M

Select item 107693503.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 106556374.

Regulation of NKT cell development by SAP, the protein defective in XLP

Kim E Nichols, Jamie Hom, Shun-You Gong, Arupa Ganguly, Cindy S Ma, Jennifer L Cannons, Stuart G Tangye, Pamela L Schwartzberg, Gary A Koretzky, Paul L Stein

Nat Med. Author manuscript; available in PMC 2023 Nov 17.

Published in final edited form as: Nat Med. 2005 Mar; 11(3): 340–345. Published online 2005 Feb 13. doi: 10.1038/nm1189

PMCID:: PMC10655637

Abstract Article PDF–1.1M

Select item 105153055.

Role of Fyn and the interleukin-6-STAT-3-autophagy axis in sarcopenia

Tsuyoshi Sasaki, Eijiro Yamada, Ryota Uehara, Shuichi Okada, Hirotaka Chikuda, Masanobu Yamada

iScience. 2023 Oct 20; 26(10): 107717. Published online 2023 Aug 25. doi: 10.1016/j.isci.2023.107717

PMCID:: PMC10515305

Abstract Article PDF–4.6M

Select item 93964116.

FYN regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization via its effect on Arp3 in the mouse testis

Yue Yang, Mingxia Yao, Jie Zeng, Dongwang Zheng, Qin Li, Ya Ni, Xiang Xiao

Front Immunol. 2022; 13: 915274. Published online 2022 Aug 9. doi: 10.3389/fimmu.2022.915274

PMCID:: PMC9396411

Abstract Article PDF–38M

Select item 93521817.

DHF-7 Ameliorates Behavioral Disorders and White Matter Lesions by Regulating BDNF and Fyn in a Mouse Model of Schizophrenia Induced by Cuprizone and MK-801

Zheng-Yu Sun, Deng-Lei Ma, Li-Hong Gu, Xi Chen, Lan Zhang, Lin Li

Int J Neuropsychopharmacol. 2022 Jul; 25(7): 600–612. Published online 2022 Mar 30. doi: 10.1093/ijnp/pyac022

PMCID:: PMC9352181

Abstract Article PDF–80M

Select item 85263498.

Differential effects of the Src family tyrosine kinases Yes and Fyn on lipopolysaccharide-induced lung injury in mice

Jennifer K. Trittmann, Yi Jin, Yusen Liu, Leif D. Nelin

Am J Physiol Lung Cell Mol Physiol. 2021 Aug 1; 321(2): L392–L403. Published online 2021 Jun 9. doi: 10.1152/ajplung.00181.2020

Correction in:: Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1; 321(5): L988.

PMCID:: PMC8526349

Abstract Article

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 811368010.

Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson’s Disease

Hariharan Saminathan, Anamitra Ghosh, Danhui Zhang, Chunjuan Song, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy

Front Pharmacol. 2021; 12: 631375. Published online 2021 Apr 28. doi: 10.3389/fphar.2021.631375

PMCID:: PMC8113680

Abstract Article PDF–3.4M

Select item 794894711.

Disturbances in PP2A methylation and one-carbon metabolism compromise Fyn distribution, neuritogenesis, and APP regulation

Goce Taleski, Diana Schuhmacher, Henry Su, Jean-Marie Sontag, Estelle Sontag

J Biol Chem. 2021 Jan-Jun; 296: 100237. Published online 2021 Jan 7. doi: 10.1074/jbc.RA120.016069

PMCID:: PMC7948947

Abstract Article PDF–3.5M

Select item 775281212.

Fyn-tau Ablation Modifies PTZ-Induced Seizures and Post-seizure Hallmarks of Early Epileptogenesis

Marson Putra, Sreekanth Puttachary, Guanghao Liu, Gloria Lee, Thimmasettappa Thippeswamy

Front Cell Neurosci. 2020; 14: 592374. Published online 2020 Dec 8. doi: 10.3389/fncel.2020.592374

PMCID:: PMC7752812

Abstract Article PDF–12M

Select item 750271713.

CRL5-dependent regulation of the small GTPases ARL4C and ARF6 controls hippocampal morphogenesis

Jisoo S. Han, Keiko Hino, Wenzhe Li, Raenier V. Reyes, Cesar P. Canales, Adam M. Miltner, Yasmin Haddadi, Junqing Sun, Chao-Yin Chen, Anna La Torre, Sergi Simó

Proc Natl Acad Sci U S A. 2020 Sep 15; 117(37): 23073–23084. Published online 2020 Sep 1. doi: 10.1073/pnas.2002749117

PMCID:: PMC7502717

Abstract Article PDF–3.3M

Select item 748387114.

Fyn kinase mediates pro-inflammatory response in a mouse model of endotoxemia: relevance to translational research

Hariharan Saminathan, Adhithiya Charli, Jie Luo, Nikhil Panicker, Richard Gordon, Jesse M. Hostetter, Huajun Jin, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy

Eur J Pharmacol. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Eur J Pharmacol. 2020 Aug 15; 881: 173259. Published online 2020 Jun 18. doi: 10.1016/j.ejphar.2020.173259

PMCID:: PMC7483871

Abstract Article PDF–2.1M

Select item 738784515.

Fyn specifically Regulates the activity of red cell glucose-6-phosphate-dehydrogenase

Matte’ Alessandro, Lupo Francesca, Tibaldi Elena, Di Paolo Maria Luisa, Federti Enrica, Andrea Carpentieri, Piero Pucci, Brunati Anna Maria, Cesaro Luca, Turrini Francesco, Gomez Manzo Saul, Soo Young Choi, Marcial Quino Jaime, Kim Dae Won, Antonella Pantaleo, Xiuli An, Iana Iatcenko, Cappellini Maria Domenica, Forni Gian Luca, De Franceschi Lucia

Redox Biol. 2020 Sep; 36: 101639. Published online 2020 Jul 11. doi: 10.1016/j.redox.2020.101639

PMCID:: PMC7387845

Abstract Article PDF–9.9M

Select item 736247216.

Fyn depletion ameliorates tau^P301L-induced neuropathology

Guanghao Liu, Kimberly L. Fiock, Yona Levites, Todd E. Golde, Marco M. Hefti, Gloria Lee

Acta Neuropathol Commun. 2020; 8: 108. Published online 2020 Jul 14. doi: 10.1186/s40478-020-00979-6

PMCID:: PMC7362472

Abstract Article PDF–7.2M

Select item 728303417.

Fyn tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates antiglioma immune responses

Andrea Comba, Patrick J Dunn, Anna E Argento, Padma Kadiyala, Maria Ventosa, Priti Patel, Daniel B Zamler, Felipe J Núñez, Lili Zhao, Maria G Castro, Pedro R Lowenstein

Neuro Oncol. 2020 Jun; 22(6): 806–818. Published online 2020 Jan 17. doi: 10.1093/neuonc/noaa006

Correction in:: Neuro Oncol. 2021 Aug; 23(8): 1413.

PMCID:: PMC7283034

Abstract Article PDF–26M

Select item 722702818.

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931

PMCID:: PMC7227028

Abstract Article PDF–5.4M

Select item 721342619.

Fyn kinase is a novel modulator of erythropoietin signaling and stress erythropoiesis

Elisabetta Beneduce, Alessandro Matte, Luigia De Falco, Serge Mbiandjeu, Deborah Chiabrando, Emanuela Tolosano, Enrica Federti, Sara Petrillo, Narla Mohandas, Angela Siciliano, Wilson Babu, Vijay Menon, Saghi Ghaffari, Achille Iolascon, Lucia De Franceschi

Am J Hematol. Author manuscript; available in PMC 2020 May 11.

Published in final edited form as: Am J Hematol. 2019 Jan; 94(1): 10–20. Published online 2018 Oct 25. doi: 10.1002/ajh.25295

PMCID:: PMC7213426

Abstract Article PDF–1.3M

Select item 711617520.

Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach

Surangi N. Perera, Ruth M. Williams, Rachel Lyne, Oliver Stubbs, Dennis P. Buehler, Tatjana Sauka-Spengler, Masaharu Noda, Gos Micklem, E. Michelle Southard-Smith, Clare V. H. Baker

Glia. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Glia. 2020 Dec 1; 68(12): 2550–2584. Published online 2020 Aug 28. doi: 10.1002/glia.23870

PMCID:: PMC7116175

Abstract Article PDF–8.9M

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