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Select item 110154971.

Y chromosome damage underlies testicular abnormalities in ATR-X syndrome

Nayla Y. León, Thanh Nha Uyen Le, Andrew Garvie, Lee H. Wong, Stefan Bagheri-Fam, Vincent R. Harley

iScience. 2024 May 17; 27(5): 109629. Published online 2024 Mar 28. doi: 10.1016/j.isci.2024.109629

PMCID:: PMC11015497

Abstract Article PDF–4.6M

Select item 109402942.

Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2

Jingjing Zhang, Mario Ruiz, Per-Olof Bergh, Marcus Henricsson, Nena Stojanović, Ranjan Devkota, Marius Henn, Mohammad Bohlooly-Y, Abrahan Hernández-Hernández, Manfred Alsheimer, Jan Borén, Marc Pilon, Hiroki Shibuya

Nat Commun. 2024; 15: 2315. Published online 2024 Mar 14. doi: 10.1038/s41467-024-46718-6

PMCID:: PMC10940294

Abstract Article PDF–6.0M

Select item 95372933.

Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development

Sergio Piñeiro-Hermida, Paula Martínez, Giuseppe Bosso, Juana María Flores, Sarita Saraswati, Jane Connor, Raphael Lemaire, Maria A. Blasco

Nat Commun. 2022; 13: 5656. Published online 2022 Oct 6. doi: 10.1038/s41467-022-32771-6

PMCID:: PMC9537293

Abstract Article PDF–20M

Select item 89313624.

FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis

Nobuhiro Tanno, Kazumasa Takemoto, Yuki Takada-Horisawa, Ryuki Shimada, Sayoko Fujimura, Naoki Tani, Naoki Takeda, Kimi Araki, Kei-ichiro Ishiguro

iScience. 2022 Apr 15; 25(4): 104008. Published online 2022 Mar 1. doi: 10.1016/j.isci.2022.104008

PMCID:: PMC8931362

Abstract Article PDF–9.0M

Select item 85848525.

Molecular Consequences of Depression Treatment: A Potential In Vitro Mechanism for Antidepressants-Induced Reprotoxic Side Effects

Przemysław Sołek, Jennifer Mytych, Anna Tabęcka-Łonczyńska, Marek Koziorowski

Int J Mol Sci. 2021 Nov; 22(21): 11855. Published online 2021 Nov 1. doi: 10.3390/ijms222111855

PMCID:: PMC8584852

Abstract Article PDF–21M

Select item 84483466.

IGSF11 is required for pericentric heterochromatin dissociation during meiotic diplotene

Bo Chen, Gengzhen Zhu, An Yan, Jing He, Yang Liu, Lin Li, Xuerui Yang, Chen Dong, Kehkooi Kee

PLoS Genet. 2021 Sep; 17(9): e1009778. Published online 2021 Sep 7. doi: 10.1371/journal.pgen.1009778

PMCID:: PMC8448346

Abstract Article PDF–8.7M

Select item 77346007.

Lymphatic Proliferation Ameliorates Pulmonary Fibrosis after Lung Injury

Peter Baluk, Ram P. Naikawadi, Shineui Kim, Felipe Rodriguez, Dongwon Choi, Young-Kwon Hong, Paul J. Wolters, Donald M. McDonald

Am J Pathol. 2020 Dec; 190(12): 2355–2375. doi: 10.1016/j.ajpath.2020.08.018

PMCID:: PMC7734600

Abstract Article PDF–7.6M

Select item 73129868.

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion

Isabel Gómez-Redondo, Priscila Ramos-Ibeas, Eva Pericuesta, Raúl Fernández-González, Ricardo Laguna-Barraza, Alfonso Gutiérrez-Adán

Int J Mol Sci. 2020 Jun; 21(11): 4115. Published online 2020 Jun 9. doi: 10.3390/ijms21114115

PMCID:: PMC7312986

Abstract Article PDF–1.8M

Select item 71456859.

FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis

Rong Hua, Huafang Wei, Chao Liu, Yue Zhang, Siyu Liu, Yueshuai Guo, Yiqiang Cui, Xin Zhang, Xuejiang Guo, Wei Li, Mingxi Liu

Nucleic Acids Res. 2019 Dec 16; 47(22): 11755–11770. Published online 2019 Nov 14. doi: 10.1093/nar/gkz992

PMCID:: PMC7145685

Abstract Article PDF–4.2M

Select item 698687310.

TRF1 averts chromatin remodelling, recombination and replication dependent-break induced replication at mouse telomeres

Rosa Maria Porreca, Emilia Herrera-Moyano, Eleni Skourti, Pui Pik Law, Roser Gonzalez Franco, Alex Montoya, Peter Faull, Holger Kramer, Jean-Baptiste Vannier

eLife. 2020; 9: e49817. Published online 2020 Jan 14. doi: 10.7554/eLife.49817

PMCID:: PMC6986873

Abstract Article PDF–5.8M

Select item 670192711.

TERRA regulate the transcriptional landscape of pluripotent cells through TRF1-dependent recruitment of PRC2

Rosa María Marión, Juan J Montero, Isabel López de Silanes, Osvaldo Graña-Castro, Paula Martínez, Stefan Schoeftner, José Alejandro Palacios-Fábrega, Maria A Blasco

eLife. 2019; 8: e44656. Published online 2019 Aug 20. doi: 10.7554/eLife.44656

PMCID:: PMC6701927

Abstract Article PDF–3.4M

Select item 669391212.

The histone modification reader ZCWPW1 is required for meiosis prophase I in male but not in female mice

Miao Li, Tao Huang, Meng-Jing Li, Chuan-Xin Zhang, Xiao-Chen Yu, Ying-Ying Yin, Chao Liu, Xin Wang, Hai-Wei Feng, Tuo Zhang, Mo-Fang Liu, Chun-Sheng Han, Gang Lu, Wei Li, Jin-Long Ma, Zi-Jiang Chen, Hong-Bin Liu, Kui Liu

Sci Adv. 2019 Aug; 5(8): eaax1101. Published online 2019 Aug 14. doi: 10.1126/sciadv.aax1101

PMCID:: PMC6693912

Abstract Article PDF–15M

Select item 636189813.

The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope

Yan Wang, Yanyan Chen, Juan Chen, Lijun Wang, Leitong Nie, Juanjuan Long, Haishuang Chang, Jian Wu, Chenhui Huang, Ming Lei

Nat Commun. 2019; 10: 564. Published online 2019 Feb 4. doi: 10.1038/s41467-019-08437-1

PMCID:: PMC6361898

Abstract Article PDF–8.0M

Select item 634074414.

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

Dvir Aran, Agnieszka P. Looney, Leqian Liu, Esther Wu, Valerie Fong, Austin Hsu, Suzanna Chak, Ram P. Naikawadi, Paul J. Wolters, Adam R. Abate, Atul J. Butte, Mallar Bhattacharya

Nat Immunol. Author manuscript; available in PMC 2019 Jul 14.

Published in final edited form as: Nat Immunol. 2019 Feb; 20(2): 163–172. Published online 2019 Jan 14. doi: 10.1038/s41590-018-0276-y

PMCID:: PMC6340744

Abstract Article PDF–1.4M

Select item 615506515.

Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis

Qianting Zhang, Jingchen Shao, Heng-Yu Fan, Chao Yu

Commun Biol. 2018; 1: 147. Published online 2018 Sep 21. doi: 10.1038/s42003-018-0154-z

PMCID:: PMC6155065

Abstract Article PDF–6.8M

Select item 610817716.

Telomeric TERB1-TRF1 interaction is crucial for male meiosis

Juanjuan Long, Chenhui Huang, Yanyan Chen, Ying Zhang, Shaohua Shi, Ligang Wu, Yie Liu, Chengyu Liu, Jian Wu, Ming Lei

Nat Struct Mol Biol. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Nat Struct Mol Biol. 2017 Dec; 24(12): 1073–1080. Published online 2017 Oct 30. doi: 10.1038/nsmb.3496

PMCID:: PMC6108177

Abstract Article PDF–1.7M

Select item 598869517.

Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis

Lina Wang, Zhaowei Tu, Chao Liu, Hongbin Liu, Philipp Kaldis, Zijiang Chen, Wei Li

Cell Death Differ. 2018 Jun; 25(6): 1174–1188. Published online 2018 Jan 8. doi: 10.1038/s41418-017-0037-8

PMCID:: PMC5988695

Abstract Article PDF–5.3M

Select item 592628018.

Mapping of Melanoma Modifier Loci in RET Transgenic Mice

Tommaso A. Dragani, Bernard Peissel, Nicola Zanesi, Alessandra Aloisi, Yan Dai, Masashi Kato, Haruhiko Suzuki, Izumi Nakashima

Jpn J Cancer Res. 2000 Nov; 91(11): 1142–1147. doi: 10.1111/j.1349-7006.2000.tb00897.x

PMCID:: PMC5926280

Summary PDF–79K

Select item 571609619.

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity

Foong Lyn Chan, Benjamin Vinod, Karel Novy, Ralf B. Schittenhelm, Cheng Huang, Maheshi Udugama, Juan Nunez-Iglesias, Jane I. Lin, Linda Hii, Julie Chan, Hilda A. Pickett, Roger J. Daly, Lee H. Wong

Nucleic Acids Res. 2017 Dec 1; 45(21): 12340–12353. Published online 2017 Oct 10. doi: 10.1093/nar/gkx904