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Items: 1 to 20 of 53

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development
Justine M. Chee, Louise Lanoue, Dave Clary, Kendall Higgins, Lynette Bower, Ann Flenniken, Ruolin Guo, David J. Adams, Fatima Bosch, Robert E. Braun, Steve D. M. Brown, H.-J. Genie Chin, Mary E. Dickinson, Chih-Wei Hsu, Michael Dobbie, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D. Heaney, Yann Herault, Martin Hrabe de Angelis, Fabio Mammano, Lauryl M. J. Nutter, Helen Parkinson, Chuan Qin, Toshi Shiroishi, Radislav Sedlacek, J-K Seong, Ying Xu, The International Mouse Phenotyping Consortium, Brian Brooks, Colin McKerlie, K. C. Kent Lloyd, Henrik Westerberg, Ala Moshiri
BMC Biol. 2023; 21: 22. Published online 2023 Feb 3. doi: 10.1186/s12915-022-01475-0
PMCID:
PMC9898963
AbstractArticlePDF–2.0M
3.
The m6A methyltransferase METTL3 regulates muscle maintenance and growth in mice
Jennifer M. Petrosino, Scott A. Hinger, Volha A. Golubeva, Juan M. Barajas, Lisa E. Dorn, Chitra C. Iyer, Hui-Lung Sun, W. David Arnold, Chuan He, Federica Accornero
Nat Commun. 2022; 13: 168. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27848-7
PMCID:
PMC8748755
AbstractArticlePDF–2.2M
4.
Local versus systemic control of bone and skeletal muscle mass by components of the transforming growth factor-β signaling pathway
Yewei Liu, Adam Lehar, Renata Rydzik, Harshpreet Chandok, Yun-Sil Lee, Daniel W. Youngstrom, Joshy George, Martin M. Matzuk, Emily L. Germain-Lee, Se-Jin Lee
Proc Natl Acad Sci U S A. 2021 Aug 17; 118(33): e2111401118. Published online 2021 Aug 12. doi: 10.1073/pnas.2111401118
PMCID:
PMC8379946
AbstractArticlePDF–1.8M
5.
Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis
Diana Monsivais, Takashi Nagashima, Renata Prunskaite-Hyyryläinen, Kaori Nozawa, Keisuke Shimada, Suni Tang, Clark Hamor, Julio E. Agno, Fengju Chen, Ramya P. Masand, Steven L. Young, Chad J. Creighton, Francesco J. DeMayo, Masahito Ikawa, Se-Jin Lee, Martin M. Matzuk
Nat Commun. 2021; 12: 3386. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23571-5
PMCID:
PMC8184938
AbstractArticlePDF–18M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Development of a Highly Sensitive ELISA for Measurement of FSH in Serum, Plasma, and Whole Blood in Mice
Luisina Ongaro, Carlos Agustin Isidro Alonso, Xiang Zhou, Emilie Brûlé, Yining Li, Gauthier Schang, Albert F Parlow, Frederik Steyn, Daniel J Bernard
Endocrinology. 2021 Apr; 162(4): bqab014. Published online 2021 Jan 21. doi: 10.1210/endocr/bqab014
PMCID:
PMC7894055
AbstractArticle
8.
Murine FSH Production Depends on the Activin Type II Receptors ACVR2A and ACVR2B
Gauthier Schang, Luisina Ongaro, Hailey Schultz, Ying Wang, Xiang Zhou, Emilie Brûlé, Ulrich Boehm, Se-Jin Lee, Daniel J Bernard
Endocrinology. 2020 Jul; 161(7): bqaa056. Published online 2020 Apr 9. doi: 10.1210/endocr/bqaa056
PMCID:
PMC7286621
AbstractArticle
9.
Parcellation of the striatal complex into dorsal and ventral districts
Shih-Yun Chen, Kuan-Ming Lu, Hsin-An Ko, Ting-Hao Huang, Janice Hsin-Jou Hao, Yu-Ting Yan, Sunny Li-Yun Chang, Sylvia M. Evans, Fu-Chin Liu
Proc Natl Acad Sci U S A. 2020 Mar 31; 117(13): 7418–7429. Published online 2020 Mar 13. doi: 10.1073/pnas.1921007117
PMCID:
PMC7132256
AbstractArticlePDF–4.5M
10.
The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage
Weiguang Wang, Hyelim Chun, Jongseung Baek, Joshua Elyahu Sadik, Anna Shirazyan, Peyman Razavi, Noah Lopez, Karen M. Lyons
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15570–15579. Published online 2019 Jul 16. doi: 10.1073/pnas.1902927116
PMCID:
PMC6681752
AbstractArticlePDF–2.4M
11.
The activin receptor is stimulated in the skeleton, vasculature, heart and kidney during chronic kidney disease.
Matthew J. Williams, Toshifumi Sugatani, Olga A. Agapova, Yifu Fang, Joseph P. Gaut, Marie-Claude Faugere, Hartmut H. Malluche, Keith A. Hruska
Kidney Int. Author manuscript; available in PMC 2019 Jul 15.
Published in final edited form as: Kidney Int. 2018 Jan; 93(1): 147–158. Published online 2017 Aug 23. doi: 10.1016/j.kint.2017.06.016
PMCID:
PMC6628245
AbstractArticlePDF–956K
12.
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System
Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund
Gastroenterology. 2018 Feb; 154(3): 624–636. doi: 10.1053/j.gastro.2017.10.005
PMCID:
PMC6381388
AbstractArticle
13.
Adenovirus-mediated knockdown of activin A receptor type 2A attenuates immune-induced hepatic fibrosis in mice and inhibits interleukin-17-induced activation of primary hepatic stellate cells
Hongjun Zhang, Baoling Ju, Ying Nie, Baohui Song, Yuanhong Xu, Ping Gao
Int J Mol Med. 2018 Jul; 42(1): 279–289. Published online 2018 Mar 29. doi: 10.3892/ijmm.2018.3600
PMCID:
PMC5979935
AbstractArticlePDF–1.6M
14.
The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors
Luca Caputo, Hagen R. Witzel, Petros Kolovos, Sirisha Cheedipudi, Mario Looso, Athina Mylona, Wilfred F.J. van IJcken, Karl-Ludwig Laugwitz, Sylvia M. Evans, Thomas Braun, Eric Soler, Frank Grosveld, Gergana Dobreva
Cell Stem Cell. Author manuscript; available in PMC 2018 Mar 27.
Published in final edited form as: Cell Stem Cell. 2015 Sep 3; 17(3): 287–299. Published online 2015 Aug 27. doi: 10.1016/j.stem.2015.08.007
PMCID:
PMC5870759
AbstractArticlePDF–2.5M
15.
Cerebral vein malformations result from loss of Twist1 expression and BMP signaling from skull progenitor cells and dura
Max A. Tischfield, Caroline D. Robson, Nicole M. Gilette, Shek Man Chim, Folasade A. Sofela, Michelle M. DeLisle, Alon Gelber, Brenda J. Barry, Sarah MacKinnon, Linda R. Dagi, Jeremy Nathans, Elizabeth C. Engle
Dev Cell. Author manuscript; available in PMC 2018 Sep 11.
Published in final edited form as: Dev Cell. 2017 Sep 11; 42(5): 445–461.e5. Published online 2017 Aug 30. doi: 10.1016/j.devcel.2017.07.027
PMCID:
PMC5595652
AbstractArticlePDF–2.0M
16.
Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass
Brian C. Goh, Vandana Singhal, Angelica J. Herrera, Ryan E. Tomlinson, Soohyun Kim, Marie-Claude Faugere, Emily L. Germain-Lee, Thomas L. Clemens, Se-Jin Lee, Douglas J. DiGirolamo
J Biol Chem. 2017 Aug 18; 292(33): 13809–13822. Published online 2017 Jun 28. doi: 10.1074/jbc.M117.782128
PMCID:
PMC5566533
AbstractArticlePDF–3.1M
17.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
18.
ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments
Shinji Hatakeyama, Serge Summermatter, Marie Jourdain, Stefan Melly, Giulia C. Minetti, Estelle Lach-Trifilieff
Skelet Muscle. 2016; 6: 26. Published online 2016 Jul 26. doi: 10.1186/s13395-016-0098-2
PMCID:
PMC4960708
AbstractArticlePDF–1004K
19.
Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation
Jia Liu, Kan Saito, Yuriko Maruya, Takashi Nakamura, Aya Yamada, Emiko Fukumoto, Momoko Ishikawa, Tsutomu Iwamoto, Kanako Miyazaki, Keigo Yoshizaki, Lihong Ge, Satoshi Fukumoto
Sci Rep. 2016; 6: 23670. Published online 2016 Mar 31. doi: 10.1038/srep23670
PMCID:
PMC4814822
AbstractArticlePDF–1.8M
20.
Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins
Vahan B. Indjeian, Garrett A. Kingman, Felicity C. Jones, Catherine A. Guenther, Jane Grimwood, Jeremy Schmutz, Richard M. Myers, David M. Kingsley
Cell. Author manuscript; available in PMC 2017 Jan 14.
Published in final edited form as: Cell. 2016 Jan 14; 164(0): 45–56. Published online 2016 Jan 7. doi: 10.1016/j.cell.2015.12.007
PMCID:
PMC4759241
AbstractArticlePDF–2.7M

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