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Select item 110146571.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 104036402.

Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth

Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima

Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916

PMCID:: PMC10403640

Abstract Article PDF–2.1M

Select item 103712523.

Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralization in mice

Léa Loisay, Davide Komla-Ebri, Anne Morice, Yann Heuzé, Camille Viaut, Amélie de La Seiglière, Nabil Kaci, Danny Chan, Audrey Lamouroux, Geneviève Baujat, J.H. Duncan Bassett, Graham R. Williams, Laurence Legeai-Mallet

JCI Insight. 2023 Jun 22; 8(12): e168796. Published online 2023 Jun 22. doi: 10.1172/jci.insight.168796

PMCID:: PMC10371252

Abstract Article PDF–16M

Select item 102682404.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 102566855.

Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate

Mahdia Taieb, Dima Ghannoum, Lydia Barré, Mohamed Ouzzine

Cell Death Dis. 2023 Jun; 14(6): 355. Published online 2023 Jun 9. doi: 10.1038/s41419-023-05875-0

PMCID:: PMC10256685

Abstract Article PDF–8.3M

Select item 101214686.

Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia

Sophie Patzek, Zhe Liu, Sean de la O, Sean Chang, Lauren E. Byrnes, Xiuqin Zhang, David M. Ornitz, Julie B. Sneddon

iScience. 2023 Apr 21; 26(4): 106500. Published online 2023 Mar 25. doi: 10.1016/j.isci.2023.106500

PMCID:: PMC10121468

Abstract Article PDF–12M

Select item 98985527.

Inhibition of miR338 rescues cleidocranial dysplasia in Runx2 mutant mice partially via the Hif1a-Vegfa axis

Runze Jin, Hanshu Zhang, Chujiao Lin, Jinqiang Guo, Weiguo Zou, Zhi Chen, Huan Liu

Exp Mol Med. 2023 Jan; 55(1): 69–80. Published online 2023 Jan 4. doi: 10.1038/s12276-022-00914-w

PMCID:: PMC9898552

Abstract Article PDF–9.9M

Select item 97713658.

TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

Jifan Feng, Xia Han, Yuan Yuan, Courtney Kyeong Cho, Eva Janečková, Tingwei Guo, Siddhika Pareek, Md Shaifur Rahman, Banghong Zheng, Jing Bi, Junjun Jing, Mingyi Zhang, Jian Xu, Thach-Vu Ho, Yang Chai

eLife. 2022; 11: e80405. Published online 2022 Dec 21. doi: 10.7554/eLife.80405

PMCID:: PMC9771365

Abstract Article PDF–17M

Select item 89064949.

FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model

Maxence Cornille, Stéphanie Moriceau, Roman H. Khonsari, Yann Heuzé, Léa Loisay, Valérie Boitez, Anne Morice, Eric Arnaud, Corinne Collet, Morad Bensidhoum, Nabil Kaci, Nathalie Boddaert, Giovanna Paternoster, Theresa Rauschendorfer, Sabine Werner, Suzanne L. Mansour, Federico Di Rocco, Franck Oury, Laurence Legeai-Mallet

J Exp Med. 2022 Apr 4; 219(4): e20201879. Published online 2022 Mar 7. doi: 10.1084/jem.20201879

PMCID:: PMC8906494

Abstract Article PDF–4.6M

Select item 888790310.

Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain

Dongjin R Lee, Christopher Rhodes, Apratim Mitra, Yajun Zhang, Dragan Maric, Ryan K Dale, Timothy J Petros

eLife. 2022; 11: e71864. Published online 2022 Feb 17. doi: 10.7554/eLife.71864

PMCID:: PMC8887903

Abstract Article PDF–15M

Select item 849232611.

Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization

Yan Yin, Meade E. Haller, Sangappa B. Chadchan, Ramakrishna Kommagani, Liang Ma

JCI Insight. 2021 Sep 8; 6(17): e150254. Published online 2021 Sep 8. doi: 10.1172/jci.insight.150254

PMCID:: PMC8492326

Abstract Article PDF–3.4M

Select item 838311912.

Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification

Asra Almubarak, Rotem Lavy, Nikola Srnic, Yawen Hu, Devi Priyanka Maripuri, Tsutomo Kume, Fred B. Berry

J Biol Chem. 2021 Sep; 297(3): 101020. Published online 2021 Jul 29. doi: 10.1016/j.jbc.2021.101020

PMCID:: PMC8383119

Abstract Article PDF–7.9M

Select item 831323913.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 828984714.

Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway

Dali Zhang, Junlan Huang, Xianding Sun, Hangang Chen, Shuo Huang, Jing Yang, Xiaolan Du, Qiaoyan Tan, Fengtao Luo, Ruobin Zhang, Siru Zhou, Wanling Jiang, Zhenhong Ni, Zuqiang Wang, Min Jin, Meng Xu, Fangfang Li, Liang Chen, Mi Liu, Nan Su, Xiaoqing Luo, Liangjun Yin, Ying Zhu, Jerry Q. Feng, Di Chen, Huabing Qi, Lin Chen, Yangli Xie

Nat Commun. 2021; 12: 4391. Published online 2021 Jul 19. doi: 10.1038/s41467-021-24643-2

PMCID:: PMC8289847

Abstract Article PDF–22M

Select item 826229615.

Prevention of guanylyl cyclase–B dephosphorylation rescues achondroplastic dwarfism

Brandon M. Wagner, Jerid W. Robinson, Yun-Wen Lin, Yi-Ching Lee, Nabil Kaci, Laurence Legeai-Mallet, Lincoln R. Potter

JCI Insight. 2021 May 10; 6(9): e147832. Published online 2021 May 10. doi: 10.1172/jci.insight.147832

PMCID:: PMC8262296

Abstract Article PDF–5.6M

Select item 808457416.

An Fgfr3-activating mutation in immature murine osteoblasts affects the appendicular and craniofacial skeleton

Martin Biosse Duplan, Emilie Dambroise, Valentin Estibals, Joelle Veziers, Jérome Guicheux, Laurence Legeai-Mallet

Dis Model Mech. 2021 Apr 1; 14(4): dmm048272. Published online 2021 Apr 23. doi: 10.1242/dmm.048272

PMCID:: PMC8084574

Abstract Article

Select item 801888217.

Enriched Environment Promotes Adult Hippocampal Neurogenesis through FGFRs

Marta Grońska-Pęski, J. Tiago Gonçalves, Jean M. Hébert

J Neurosci. 2021 Mar 31; 41(13): 2899–2910. doi: 10.1523/JNEUROSCI.2286-20.2021

PMCID:: PMC8018882

Abstract Article PDF–7.8M

Select item 800904518.

Fibroblast Growth Factor 2 Modulates Hypothalamic Pituitary Axis Activity and Anxiety Behavior Through Glucocorticoid Receptors

Natalina Salmaso, Hanna E. Stevens, Jessica McNeill, Maha ElSayed, Qiuyin Ren, Maria E. Maragnoli, Michael L. Schwartz, Simone Tomasi, Robert M. Sapolsky, Ronald Duman, Flora M. Vaccarino

Biol Psychiatry. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Biol Psychiatry. 2016 Sep 15; 80(6): 479–489. Published online 2016 Mar 2. doi: 10.1016/j.biopsych.2016.02.026

PMCID:: PMC8009045

Abstract Article PDF–1.5M

Select item 795726519.

FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex

Chen Zhou, Danying Chen, Jianhan Ren, Delan Huang, Runze Li, Haotian Luo, Chenyu Guan, Yang Cao, Weicai Wang

J Cell Mol Med. 2021 Mar; 25(6): 3051–3062. Published online 2021 Feb 13. doi: 10.1111/jcmm.16351

PMCID:: PMC7957265

Abstract Article PDF–2.4M

Select item 776945820.

In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia

Diogo Gonçalves, Guylène Rignol, Pierre Dellugat, Guido Hartmann, Stephanie Sarrazy Garcia, Jeffrey Stavenhagen, Luca Santarelli, Elvire Gouze, Christian Czech

PLoS One. 2020; 15(12): e0244368. Published online 2020 Dec 28. doi: 10.1371/journal.pone.0244368