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Items: 1 to 20 of 211

1.
IL-33 Accelerates Chronic Atrophic Gastritis through AMPK-ULK1 Axis Mediated Autolysosomal Degradation of GKN1
Kewei Liu, Hongxia Huang, Mengyuan Xiong, Qiaojiao Wang, Xiantao Chen, Yinqiong Feng, Hang Ma, Wanqun Chen, Xuegang Li, Xiaoli Ye
Int J Biol Sci. 2024; 20(6): 2323–2338. Published online 2024 Apr 8. doi: 10.7150/ijbs.93573
PMCID:
PMC11008276
AbstractArticlePDF–8.2M
2.
Sirt3 Protects Retinal Pigment Epithelial Cells From High Glucose-Induced Injury by Promoting Mitophagy Through the AMPK/mTOR/ULK1 Pathway
Wei Yang, Chen Qiu, Hongbin Lv, Zhiru Zhang, Tianyu Yao, Li Huang, Guihong Wu, Xueqin Zhang, Jie Chen, Yue He
Transl Vis Sci Technol. 2024 Mar; 13(3): 19. Published online 2024 Mar 22. doi: 10.1167/tvst.13.3.19
PMCID:
PMC10981157
AbstractArticlePDF–1.3M
3.
SPHK1 potentiates colorectal cancer progression and metastasis via regulating autophagy mediated by TRAF6-induced ULK1 ubiquitination
Da Chen, Jiangni Wu, Xinze Qiu, Shibo Luo, Shanpei Huang, Erdan Wei, Mengbin Qin, Jiean Huang, Shiquan Liu
Cancer Gene Ther. 2024; 31(3): 410–419. Published online 2023 Dec 22. doi: 10.1038/s41417-023-00711-1
PMCID:
PMC10940154
AbstractArticlePDF–14M
4.
AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR‐ULK1‐autophagy axis
Li Zhu, Jiahe Wang, Zuping Wu, Sirui Chen, Yuying He, Yukun Jiang, Guowen Luo, Zhuoxuan Wu, Yuyu Li, Jing Xie, Shujuan Zou, Chenchen Zhou
Cell Prolif. 2024 Feb; 57(2): e13546. Published online 2023 Sep 20. doi: 10.1111/cpr.13546
PMCID:
PMC10849782
AbstractArticlePDF–12M
5.
Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer
Jiao Wang, Fei Zheng, Dandan Wang, Qing Yang
Cell Death Dis. 2024 Jan; 15(1): 97. Published online 2024 Jan 29. doi: 10.1038/s41419-024-06477-0
PMCID:
PMC10824720
AbstractArticlePDF–8.4M
6.
ULK1 forms distinct oligomeric states and nanoscopic structures during autophagy initiation
Chiranjib Banerjee, Dushyant Mehra, Daihyun Song, Angel Mancebo, Ji-Man Park, Do-Hyung Kim, Elias M. Puchner
Sci Adv. 2023 Sep 29; 9(39): eadh4094. Published online 2023 Sep 29. doi: 10.1126/sciadv.adh4094
Correction in:
Sci Adv. 2024 May 3; 10(18): eadp8168.
PMCID:
PMC10541014
AbstractArticlePDF–2.2M
7.
Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
Sarah J. Backe, Rebecca A. Sager, Jennifer A. Heritz, Laura A. Wengert, Katherine A. Meluni, Xavier Aran-Guiu, Barry Panaretou, Mark R. Woodford, Chrisostomos Prodromou, Dimitra Bourboulia, Mehdi Mollapour
Cell Rep. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Cell Rep. 2023 Jul 25; 42(7): 112807. Published online 2023 Jul 14. doi: 10.1016/j.celrep.2023.112807
Correction in:
Cell Rep. 2024 Jan 23; 43(1): 113672.
PMCID:
PMC10529509
AbstractArticlePDF–2.2M
8.
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation
Mengshu Jia, Xiao Yue, Weixia Sun, Qianjun Zhou, Cheng Chang, Weihua Gong, Jian Feng, Xie Li, Ruonan Zhan, Kemin Mo, Lijuan Zhang, Yajie Qian, Yuying Sun, Aoxue Wang, Yejun Zou, Weicai Chen, Yan Li, Li Huang, Yi Yang, Yuzheng Zhao, Xiawei Cheng
Sci Adv. 2023 Jun 2; 9(22): eadg4993. Published online 2023 Jun 2. doi: 10.1126/sciadv.adg4993
PMCID:
PMC10413652
AbstractArticlePDF–2.8M
9.
Phosphorylation of phase‐separated p62 bodies by ULK1 activates a redox‐independent stress response
Ryo Ikeda, Daisuke Noshiro, Hideaki Morishita, Shuhei Takada, Shun Kageyama, Yuko Fujioka, Tomoko Funakoshi, Satoko Komatsu‐Hirota, Ritsuko Arai, Elena Ryzhii, Manabu Abe, Tomoaki Koga, Hozumi Motohashi, Mitsuyoshi Nakao, Kenji Sakimura, Arata Horii, Satoshi Waguri, Yoshinobu Ichimura, Nobuo N Noda, Masaaki Komatsu
EMBO J. 2023 Jul; 42(14): e113349. Published online 2023 Jun 12. doi: 10.15252/embj.2022113349
PMCID:
PMC10350833
AbstractArticlePDF–4.4M
10.
Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules
Cuiwei Yang, Zhangshun Wang, Yingjin Kang, Qianqian Yi, Tong Wang, Yun Bai, Yanfen Liu
Autophagy. 2023; 19(7): 1934–1951. Published online 2023 Jan 24. doi: 10.1080/15548627.2022.2164427
PMCID:
PMC10283440
AbstractArticlePDF–5.2M
11.
Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
Apirat Chaikuad, Sebastian E. Koschade, Alexandra Stolz, Katarina Zivkovic, Shabnam Shaid, Huiyu Ren, Lester J. Lambert, Nicholas D.P. Cosford, Christian H. Brandts, Stefan Knapp
Biochem J. Author manuscript; available in PMC 2023 Jun 16.
Published in final edited form as: Biochem J. 2019 Mar 12; 476(5): 875–887. Published online 2019 Mar 12. doi: 10.1042/BCJ20190038
PMCID:
PMC10275411
AbstractArticlePDF–2.2M
12.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
13.
Identification of ULK1 as a novel mitophagy-related gene in diabetic nephropathy
Yuan-Yuan Yang, Zhong-Xiuzi Gao, Zi-Hui Mao, Dong-Wei Liu, Zhang-Suo Liu, Peng Wu
Front Endocrinol (Lausanne) 2022; 13: 1079465. Published online 2023 Jan 18. doi: 10.3389/fendo.2022.1079465
PMCID:
PMC9889542
AbstractArticlePDF–21M
14.
Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection
Subhash Mehto, Kautilya Kumar Jena, Rina Yadav, Swatismita Priyadarsini, Pallavi Samal, Sivaram Krishna, Kollori Dhar, Ashish Jain, Nishant Ranjan Chauhan, Krushna C Murmu, Ramyasingh Bal, Rinku Sahu, Pundrik Jaiswal, Bhabani Sankar Sahoo, Srinivas Patnaik, Thomas A Kufer, Tor Erik Rusten, Swati Chauhan, Punit Prasad, Santosh Chauhan
EMBO J. 2022 Dec; 41(23): e111289. Published online 2022 Oct 11. doi: 10.15252/embj.2022111289
PMCID:
PMC9713718
AbstractArticlePDF–14M
15.
BTN3A1 promotes tumor progression and radiation resistance in esophageal squamous cell carcinoma by regulating ULK1-mediated autophagy
Wenjing Yang, Bo Cheng, Pengxiang Chen, Xiaozheng Sun, Zhihua Wen, Yufeng Cheng
Cell Death Dis. 2022 Nov; 13(11): 984. Published online 2022 Nov 22. doi: 10.1038/s41419-022-05429-w
PMCID:
PMC9684582
AbstractArticlePDF–9.5M
16.
Vaspin Attenuates Atrial Abnormalities by Promoting ULK1/FUNDC1-Mediated Mitophagy
Yanmin Zhu, Zhoushan Gu, Jiayu Shi, Chu Chen, Haixia Xu, Qi Lu
Oxid Med Cell Longev. 2022; 2022: 3187463. Published online 2022 Nov 15. doi: 10.1155/2022/3187463
PMCID:
PMC9681551
AbstractArticlePDF–7.4M
17.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
18.
The interaction between autophagy and the epithelial-mesenchymal transition mediated by NICD/ULK1 is involved in the formation of diabetic cataracts
Jiyuan Ma, Wei Ye, Yunshu Yang, Tong Wu, Yafen Wang, Ji Li, Rui Pei, Mengmei He, Luning Zhang, Jian Zhou
Mol Med. 2022; 28: 116. Published online 2022 Sep 14. doi: 10.1186/s10020-022-00540-2
PMCID:
PMC9476327
AbstractArticlePDF–12M
19.
O-GlcNAcylation stabilizes the autophagy-initiating kinase ULK1 by inhibiting chaperone-mediated autophagy upon HPV infection
Yingxin Shi, Sheng Yan, Guang-Can Shao, Jinglong Wang, Yong-Ping Jian, Bo Liu, Yanqiu Yuan, Ke Qin, Shanshan Nai, Xiahe Huang, Yingchun Wang, Zhenghui Chen, Xing Chen, Meng-Qiu Dong, Yiqun Geng, Zhi-Xiang Xu, Jing Li
J Biol Chem. 2022 Sep; 298(9): 102341. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102341
PMCID:
PMC9436821
AbstractArticlePDF–2.0M
20.
Manganese is a physiologically relevant TORC1 activator in yeast and mammals
Raffaele Nicastro, Hélène Gaillard, Laura Zarzuela, Marie-Pierre Péli-Gulli, Elisabet Fernández-García, Mercedes Tomé, Néstor García-Rodríguez, Raúl V Durán, Claudio De Virgilio, Ralf Erik Wellinger
eLife. 2022; 11: e80497. Published online 2022 Jul 29. doi: 10.7554/eLife.80497
PMCID:
PMC9337852
AbstractArticlePDF–3.8M

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