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Items: 1 to 20 of 40

1.
A combined bioinformatics and experimental approach identifies RMI2 as a Wnt/β-catenin signaling target gene related to hepatocellular carcinoma
Hung-Wen Tsai, Shu-Wen Cheng, Chou-Cheng Chen, I-Wen Chen, Chung-Liang Ho
BMC Cancer. 2023; 23: 1025. Published online 2023 Oct 24. doi: 10.1186/s12885-023-10655-2
PMCID:
PMC10594864
AbstractArticlePDF–4.5M
2.
The MRN complex and topoisomerase IIIa–RMI1/2 synchronize DNA resection motor proteins
Michael M. Soniat, Giaochau Nguyen, Hung-Che Kuo, Ilya J. Finkelstein
J Biol Chem. 2023 Feb; 299(2): 102802. Published online 2022 Dec 16. doi: 10.1016/j.jbc.2022.102802
PMCID:
PMC9971906
AbstractArticlePDF–2.0M
3.
RecQ mediated genome instability 2 (RMI2): a potential prognostic and immunological biomarker for pan-cancers
Wei Wei, Xiaomei Ying, Liang Chen, Qingmei Sun, Xiaohuan Lu, Yang Xia, Rubin Xu, Zhechen Zhu, Dong Zhang, Qikai Tang, Li Li, Jiaheng Xie, Hongzhu Yu
Aging (Albany NY) 2022 May 15; 14(9): 4107–4136. Published online 2022 May 12. doi: 10.18632/aging.204076
PMCID:
PMC9134953
AbstractArticlePDF–16M
4.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
5.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
6.
The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom’s syndrome helicase for efficient disruption of D-loops
Gábor M. Harami, János Pálinkás, Yeonee Seol, Zoltán J. Kovács, Máté Gyimesi, Hajnalka Harami-Papp, Keir C. Neuman, Mihály Kovács
Nat Commun. 2022; 13: 654. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28208-9
PMCID:
PMC8813930
AbstractArticlePDF–1.7M
7.
Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex
Julia A. M. Bakx, Andreas S. Biebricher, Graeme A. King, Panagiotis Christodoulis, Kata Sarlós, Anna H. Bizard, Ian D. Hickson, Gijs J. L. Wuite, Erwin J. G. Peterman
Nat Commun. 2022; 13: 584. Published online 2022 Jan 31. doi: 10.1038/s41467-022-28082-5
PMCID:
PMC8803869
AbstractArticlePDF–1.9M
8.
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα
Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz
iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686
PMCID:
PMC8220391
AbstractArticlePDF–4.4M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary
Cell. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050
PMCID:
PMC8108093
AbstractArticlePDF–3.5M
11.
RMI2 plays crucial roles in growth and metastasis of lung cancer
Weixiang Zhan, Yina Liu, Ying Gao, Run Gong, Wen Wang, Ruhua Zhang, Yuanzhong Wu, Tiebang Kang, Denghui Wei
Signal Transduct Target Ther. 2020; 5: 188. Published online 2020 Sep 3. doi: 10.1038/s41392-020-00295-4
PMCID:
PMC7471275
ArticlePDF–1.3M
12.
Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability
David Pladevall-Morera, Stephanie Munk, Andreas Ingham, Lorenza Garribba, Eliene Albers, Ying Liu, Jesper V Olsen, Andres J Lopez-Contreras
Nucleic Acids Res. 2019 Sep 5; 47(15): 8004–8018. Published online 2019 Jun 10. doi: 10.1093/nar/gkz510
Correction in:
Nucleic Acids Res. 2019 Sep 5; 47(15): 8332.
PMCID:
PMC6735892
AbstractArticlePDF–5.4M
13.
PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling
Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin
Cell Rep. Author manuscript; available in PMC 2019 Jun 26.
Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060
PMCID:
PMC6594551
AbstractArticlePDF–1.4M
14.
H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids
Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth
Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.
Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9
PMCID:
PMC6420097
ArticlePDF–1.7M
15.
LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells
Philipp Trepte, Sabrina Kruse, Simona Kostova, Sheila Hoffmann, Alexander Buntru, Anne Tempelmeier, Christopher Secker, Lisa Diez, Aline Schulz, Konrad Klockmeier, Martina Zenkner, Sabrina Golusik, Kirstin Rau, Sigrid Schnoegl, Craig C Garner, Erich E Wanker
Mol Syst Biol. 2018 Jul; 14(7): e8071. Published online 2018 Jul 11. doi: 10.15252/msb.20178071
PMCID:
PMC6039870
AbstractArticlePDF–2.1M
16.
Crystal Structures of RMI1 and RMI2, Two OB-fold Regulatory Subunits of the BLM Complex
Feng Wang, Yuting Yang, Thiyam Ramsing Singh, Valeria Busygina, Rong Guo, Ke Wan, Weidong Wang, Patrick Sung, Amom Ruhikanta Meetei, Ming Lei
Structure. Author manuscript; available in PMC 2018 May 16.
Published in final edited form as: Structure. 2010 Sep 8; 18(9): 1159–1170. doi: 10.1016/j.str.2010.06.008
PMCID:
PMC5955610
AbstractArticlePDF–970K
17.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
18.
ETAA1 acts at stalled replication forks to maintain genome integrity
Thomas E. Bass, Jessica W. Luzwick, Gina Kavanaugh, Clinton Carroll, Huzefa Dungrawala, Gloria G. Glick, Michael D. Feldkamp, Reid Putney, Walter J. Chazin, David Cortez
Nat Cell Biol. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: Nat Cell Biol. 2016 Nov; 18(11): 1185–1195. Published online 2016 Oct 10. doi: 10.1038/ncb3415
PMCID:
PMC5245861
AbstractArticlePDF–2.8M
19.
Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome
Damien F. Hudson, David J. Amor, Amber Boys, Kathy Butler, Lorna Williams, Tao Zhang, Paul Kalitsis
PLoS Genet. 2016 Dec; 12(12): e1006483. Published online 2016 Dec 15. doi: 10.1371/journal.pgen.1006483
PMCID:
PMC5157948
AbstractArticlePDF–2.8M
20.
The cell proliferation antigen Ki-67 organises heterochromatin
Michal Sobecki, Karim Mrouj, Alain Camasses, Nikolaos Parisis, Emilien Nicolas, David Llères, François Gerbe, Susana Prieto, Liliana Krasinska, Alexandre David, Manuel Eguren, Marie-Christine Birling, Serge Urbach, Sonia Hem, Jérôme Déjardin, Marcos Malumbres, Philippe Jay, Vjekoslav Dulic, Denis LJ Lafontaine, Robert Feil, Daniel Fisher
eLife. 2016; 5: e13722. Published online 2016 Mar 7. doi: 10.7554/eLife.13722
PMCID:
PMC4841783
AbstractArticlePDF–5.1M

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