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Select item 112416871.

miR-146a Decreases Inflammation and ROS Production in Aged Dermal Fibroblasts

Liping Zhang, Iris C. Wang, Songmei Meng, Junwang Xu

Int J Mol Sci. 2024 Jul; 25(13): 6821. Published online 2024 Jun 21. doi: 10.3390/ijms25136821

PMCID:: PMC11241687

Abstract Article PDF–2.8M

Select item 111166402.

MiR-146a alleviates inflammatory bowel disease in mice through systematic regulation of multiple genetic networks

Fengting Zhu, Taotan Yang, Mengmeng Ning, Yang Liu, Wei Xia, Yan Fu, Ting Wen, Mei Zheng, Ruilong Xia, Ran Qian, Yang Li, Minxuan Sun, Jianping Liu, Li Tian, Qian Zhou, Xin Yu, Changgeng Peng

Front Immunol. 2024; 15: 1366319. Published online 2024 May 10. doi: 10.3389/fimmu.2024.1366319

PMCID:: PMC11116640

Abstract Article PDF–23M

Select item 111123363.

Dysregulated innate immune signaling cooperates with RUNX1 mutations to transform an MDS-like disease to AML

Laura Barreyro, Avery M. Sampson, Kathleen Hueneman, Kwangmin Choi, Susanne Christie, Vighnesh Ramesh, Michael Wyder, Dehua Wang, Mario Pujato, Kenneth D. Greis, Gang Huang, Daniel T. Starczynowski

iScience. 2024 Jun 21; 27(6): 109809. Published online 2024 Apr 24. doi: 10.1016/j.isci.2024.109809

PMCID:: PMC11112336

Abstract Article PDF–5.8M

Select item 108708224.

MicroRNA-146b protects kidney injury during urinary tract infections by modulating macrophage polarization

Changying Wang, Hongyan Cheng, Fenglian Yan, Hui Zhang, Junfeng Zhang, Chunxia Li, Mingsheng Zhao, Dongmei Shi, Huabao Xiong

mBio. 2023 Nov-Dec; 14(6): e02094-23. Published online 2023 Nov 1. doi: 10.1128/mbio.02094-23

PMCID:: PMC10870822

Abstract Article PDF–7.7M

Select item 105435685.

miR-146a-3p as a potential novel therapeutic by targeting MBD2 to mediate Th17 differentiation in Th17 predominant neutrophilic severe asthma

Wentao Duan, Jin Huang, Binaya Wasti, Zhifeng Chen, Yu Yuan, Yi He, Danhong Li, Jingsi Jia, Shaokun Liu, Yi Liu, Libing Ma, Qingping Zeng, Liming zhu, Jianmin Li, Xiufeng Zhang, Xudong Xiang

Clin Exp Med. 2023; 23(6): 2839–2854. Published online 2023 Mar 24. doi: 10.1007/s10238-023-01033-0

PMCID:: PMC10543568

Abstract Article PDF–1.7M

Select item 103360506.

MicroRNA-146a negatively regulates inflammation via the IRAK1/TRAF6/NF-κB signaling pathway in dry eye

Ruifang Han, Juan Gao, Liming Wang, Peng Hao, Xi Chen, Yuchuan Wang, Zhixin Jiang, Li Jiang, Ting Wang, Lin Zhu, Xuan Li

Sci Rep. 2023; 13: 11192. Published online 2023 Jul 11. doi: 10.1038/s41598-023-38367-4

PMCID:: PMC10336050

Abstract Article PDF–2.8M

Select item 101129977.

MicroRNA-146a Promotes Embryonic Stem Cell Differentiation towards Vascular Smooth Muscle Cells through Regulation of Kruppel-like Factor 4

Qing Zhang, Rong-rong Pan, Yu-tao Wu, Yu-miao Wei

Curr Med Sci. 2023; 43(2): 223–231. Published online 2023 Apr 19. doi: 10.1007/s11596-023-2736-3

PMCID:: PMC10112997

Abstract Article PDF–1.1M

Select item 100025078.

MiR-146a in ALS: Contribution to Early Peripheral Nerve Degeneration and Relevance as Disease Biomarker

Eleonora Giagnorio, Claudia Malacarne, Paola Cavalcante, Letizia Scandiffio, Marco Cattaneo, Viviana Pensato, Cinzia Gellera, Nilo Riva, Angelo Quattrini, Eleonora Dalla Bella, Giuseppe Lauria, Renato Mantegazza, Silvia Bonanno, Stefania Marcuzzo

Int J Mol Sci. 2023 Mar; 24(5): 4610. Published online 2023 Feb 27. doi: 10.3390/ijms24054610

PMCID:: PMC10002507

Abstract Article PDF–3.0M

Select item 98560589.

Silencing miR-146a-5p Protects against Injury-Induced Osteoarthritis in Mice

Haocheng Qin, Cuicui Wang, Yonghua He, Aiwu Lu, Tiandao Li, Bo Zhang, Jie Shen

Biomolecules. 2023 Jan; 13(1): 123. Published online 2023 Jan 7. doi: 10.3390/biom13010123

PMCID:: PMC9856058

Abstract Article PDF–4.4M

Select item 951114910.

Regulation of T-independent B-cell responses by microRNA-146a

Jennifer K. King, Tiffany M. Tran, May H. Paing, Yuxin Yin, Amit K. Jaiswal, Ching-Hsuan Tso, Koushik Roy, David Casero, Dinesh S. Rao

Front Immunol. 2022; 13: 984302. Published online 2022 Sep 12. doi: 10.3389/fimmu.2022.984302

PMCID:: PMC9511149

Abstract Article PDF–6.0M

Select item 944713811.

TLR7 Mediates Acute Respiratory Distress Syndrome in Sepsis by Sensing Extracellular miR-146a

Huang Huang, Jing Zhu, Lili Gu, Jiang Hu, Xiujing Feng, Weiliang Huang, Sheng Wang, Yang Yang, Ping Cui, Shao-Hsuan Lin, Andrew Suen, Briana K. Shimada, Brittney Williams, Maureen A. Kane, Yunbo Ke, Chen-ou Zhang, Anna A. Birukova, Konstantin G. Birukov, Wei Chao, Lin Zou

Am J Respir Cell Mol Biol. 2022 Sep; 67(3): 375–388. Published online 2022 Jun 9. doi: 10.1165/rcmb.2021-0551OC

PMCID:: PMC9447138

Abstract Article PDF–3.0M

Select item 943565112.

Bone marrow–confined IL-6 signaling mediates the progression of myelodysplastic syndromes to acute myeloid leukemia

Yang Mei, Kehan Ren, Yijie Liu, Annabel Ma, Zongjun Xia, Xu Han, Ermin Li, Hamza Tariq, Haiyan Bao, Xinshu Xie, Cheng Zou, Dingxiao Zhang, Zhaofeng Li, Lili Dong, Amit Verma, Xinyan Lu, Yasmin Abaza, Jessica K. Altman, Madina Sukhanova, Jing Yang, Peng Ji

J Clin Invest. 2022 Sep 1; 132(17): e152673. Published online 2022 Sep 1. doi: 10.1172/JCI152673

PMCID:: PMC9435651

Abstract Article PDF–24M

Select item 941393013.

Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage

Yu-Tung Hsieh, Yu-Chi Chou, Pin-Yu Kuo, Hung-Wen Tsai, Yi-Ting Yen, Ai-Li Shiau, Chrong-Reen Wang

J Biomed Sci. 2022; 29: 62. Published online 2022 Aug 26. doi: 10.1186/s12929-022-00849-4

PMCID:: PMC9413930

Abstract Article PDF–5.1M

Select item 934325214.

CD147 a direct target of miR-146a supports energy metabolism and promotes tumor growth in ALK+ ALCL

Ivonne-Aidee Montes-Mojarro, Julia Steinhilber, Christoph M. Griessinger, Achim Rau, Ann-Kathrin Gersmann, Ursula Kohlhofer, Petra Fallier-Becker, Huan-Chang Liang, Ute Hofmann, Mathias Haag, Wolfram Klapper, Elke Schaeffeler, Bernd J. Pichler, Matthias Schwab, Falko Fend, Irina Bonzheim, Leticia Quintanilla-Martinez

Leukemia. 2022; 36(8): 2050–2063. Published online 2022 Jun 8. doi: 10.1038/s41375-022-01617-x

PMCID:: PMC9343252

Abstract Article PDF–5.3M

Select item 927598715.

MicroRNA-146 attenuates lipopolysaccharide induced ovarian dysfunction by inhibiting the TLR4/NF- κB signaling pathway

Fengping He, Yanhui Liu, Tang Li, Qiulin Ma, Zhang Yongmei, Peiqing He, Chuanyin Xiong

Bioengineered. 2022; 13(5): 11611–11623. Published online 2022 May 8. doi: 10.1080/21655979.2022.2070584

PMCID:: PMC9275987

Abstract Article PDF–2.0M

Select item 920211816.

MiR-146a-5p, targeting ErbB4, promotes 3T3-L1 preadipocyte differentiation through the ERK1/2/PPAR-γ signaling pathway

Yifen Wang, Jie Zhang, Xueru Chu, Mengke Wang, Yongning Xin, Shousheng Liu

Lipids Health Dis. 2022; 21: 54. Published online 2022 Jun 15. doi: 10.1186/s12944-022-01662-6

PMCID:: PMC9202118

Abstract Article PDF–7.9M

Select item 908536417.

Role of Cardiomyocyte-Derived Exosomal MicroRNA-146a-5p in Macrophage Polarization and Activation

Cong Chen, Sidong Cai, Min Wu, Run Wang, Mingya Liu, Gaozhen Cao, Min Dong, Kai-Hang Yiu

Dis Markers. 2022; 2022: 2948578. Published online 2022 May 2. doi: 10.1155/2022/2948578

PMCID:: PMC9085364

Abstract Article PDF–2.3M

Select item 902253918.

Target-Dependent Coordinated Biogenesis of Secondary MicroRNAs by miR-146a Balances Macrophage Activation Processes

Susanta Chatterjee, Ishita Mukherjee, Shreya Bhattacharjee, Mainak Bose, Saikat Chakrabarti, Suvendra N. Bhattacharyya

Mol Cell Biol. 2022 Apr; 42(4): e00452-21. Published online 2022 Mar 21. doi: 10.1128/mcb.00452-21

PMCID:: PMC9022539

Abstract Article PDF–8.0M

Select item 881100219.

miR-146a-5p modulates cellular senescence and apoptosis in visceral adipose tissue of long-lived Ames dwarf mice and in cultured pre-adipocytes

Allancer D. C. Nunes, Moritz Weigl, Augusto Schneider, Sarah Noureddine, Lin Yu, Collin Lahde, Tatiana Dandolini Saccon, Kunal Mitra, Esther Beltran, Johannes Grillari, James L. Kirkland, Tamara Tchkonia, Paul D. Robbins, Michal M. Masternak

GeroScience. 2022 Feb; 44(1): 503–518. Published online 2021 Nov 25. doi: 10.1007/s11357-021-00490-3

PMCID:: PMC8811002

Abstract Article PDF–1.6M

Select item 876693720.

Brain innate immune response via miRNA-TLR7 sensing in polymicrobial sepsis

Lin Zou, Junyun He, Lili Gu, Rami A. Shahror, Yun Li, Tuoxin Cao, Sheng Wang, Jing Zhu, Huang Huang, Fengqian Chen, Xiaoxuan Fan, Junfang Wu, Wei Chao

Brain Behav Immun. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Brain Behav Immun. 2022 Feb; 100: 10–24. Published online 2021 Nov 19. doi: 10.1016/j.bbi.2021.11.007