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Select item 109457071.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 103988942.

The E3 ligase Poe promotes Pericentrin degradation

Brian J. Galletta, Ramya Varadarajan, Carey J. Fagerstrom, Bing Yang, Karen Plevock Haase, Katherine McJunkin, Nasser M. Rusan

Mol Biol Cell. 2023 Aug 1; 34(9): br15. Published online 2023 Aug 1. doi: 10.1091/mbc.E22-11-0534

PMCID:: PMC10398894

Abstract Article PDF–4.7M

Select item 101057363.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 100823674.

PERK prevents rhodopsin degradation during retinitis pigmentosa by inhibiting IRE1-induced autophagy

Ning Zhao, Ning Li, Tao Wang

J Cell Biol. 2023 May 1; 222(5): e202208147. Published online 2023 Apr 6. doi: 10.1083/jcb.202208147

PMCID:: PMC10082367

Abstract Article PDF–8.9M

Select item 94093195.

Comparative Ubiquitome Analysis Reveals Deubiquitinating Effects Induced by Wolbachia Infection in Drosophila melanogaster

Qiong Zong, Bin Mao, Hua-Bao Zhang, Bing Wang, Wen-Juan Yu, Zhi-Wei Wang, Yu-Feng Wang

Int J Mol Sci. 2022 Aug; 23(16): 9459. Published online 2022 Aug 21. doi: 10.3390/ijms23169459

PMCID:: PMC9409319

Abstract Article PDF–3.4M

Select item 87005546.

Differential Dose- and Tissue-Dependent Effects of foxo on Aging, Metabolic and Proteostatic Pathways

Maria S. Manola, Sentiljana Gumeni, Ioannis P. Trougakos

Cells. 2021 Dec; 10(12): 3577. Published online 2021 Dec 18. doi: 10.3390/cells10123577

PMCID:: PMC8700554

Abstract Article PDF–17M

Select item 86644867.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 81724688.

Proteasome Stress in Skeletal Muscle Mounts a Long-Range Protective Response that Delays Retinal and Brain Aging

Mamta Rai, Zane Coleman, Michelle Curley, Anjana Nityanandam, Anna Platt, Maricela Robles-Murguia, Jianqin Jiao, David Finkelstein, Yong-Dong Wang, Beisi Xu, Yiping Fan, Fabio Demontis

Cell Metab. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Cell Metab. 2021 Jun 1; 33(6): 1137–1154.e9. Published online 2021 Mar 26. doi: 10.1016/j.cmet.2021.03.005

PMCID:: PMC8172468

Abstract Article PDF–4.2M

Select item 77872589.

Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila

Stanley Walls, Soda Diop, Ryan Birse, Lisa Elmen, Zhuohui Gan, Sreehari Kalvakuri, Santiago Pineda, Curran Reddy, Erika Taylor, Bosco Trinh, Georg Vogler, Rachel Zarndt, Andrew McCulloch, Peter Lee, Sharmila Bhattacharya, Rolf Bodmer, Karen Ocorr

Cell Rep. Author manuscript; available in PMC 2021 Jan 6.

Published in final edited form as: Cell Rep. 2020 Dec 8; 33(10): 108445. Published online 2020 Nov 25. doi: 10.1016/j.celrep.2020.108445

PMCID:: PMC7787258

Abstract Article PDF–1.5M

Select item 770455910.

The Proteasome Beta 5 Subunit is Essential for Sexually Divergent Adaptive Homeostatic Responses to Oxidative Stress in D. melanogaster

Laura CD Pomatto, Christina Sisliyan, Sarah Wong, Mayme Cline, John Tower, Kelvin J. A. Davies

Free Radic Biol Med. Author manuscript; available in PMC 2021 Nov 20.

Published in final edited form as: Free Radic Biol Med. 2020 Nov 20; 160: 67–77. Published online 2020 Aug 3. doi: 10.1016/j.freeradbiomed.2020.07.003

PMCID:: PMC7704559

Abstract Article PDF–983K

Select item 736935411.

Rpt2 proteasome subunit reduction causes Parkinson's disease like symptoms in Drosophila

Iván Fernández-Cruz, Iván Sánchez-Díaz, Verónica Narváez-Padilla, Enrique Reynaud

IBRO Rep. 2020 Dec; 9: 65–77. Published online 2020 Jul 11. doi: 10.1016/j.ibror.2020.07.001

PMCID:: PMC7369354

Abstract Article PDF–2.8M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 675092613.

Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis

Jia Zhou, Lingna Xu, Xiuying Duan, Wei Liu, Xiaocui Zhao, Xi Wang, Weina Shang, Xuefei Fang, Huan Yang, Lijun Jia, Jian Bai, Jiayao Zhao, Liquan Wang, Chao Tong

Sci Adv. 2019 Sep; 5(9): eaax0365. Published online 2019 Sep 18. doi: 10.1126/sciadv.aax0365

PMCID:: PMC6750926

Abstract Article PDF–14M

Select item 673554114.

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

Eleni N. Tsakiri, Sentiljana Gumeni, Konstantinos Vougas, Diana Pendin, Issidora Papassideri, Andrea Daga, Vassilis Gorgoulis, Gábor Juhász, Luca Scorrano, Ioannis P. Trougakos

Autophagy. 2019; 15(10): 1757–1773. Published online 2019 Apr 19. doi: 10.1080/15548627.2019.1596477

PMCID:: PMC6735541

Abstract Article PDF–7.3M

Select item 661073415.

Alterations in Organismal Physiology, Impaired Stress Resistance, and Accelerated Aging in Drosophila Flies Adapted to Multigenerational Proteome Instability

Maria S. Manola, Eleni N. Tsakiri, Ioannis P. Trougakos

Oxid Med Cell Longev. 2019; 2019: 7823285. Published online 2019 Jun 11. doi: 10.1155/2019/7823285

PMCID:: PMC6610734

Abstract Article PDF–3.4M

Select item 655349916.

Organelle aging: lessons from model organisms

Mark Bouska, Kerui Huang, Ping Kang, Hua Bai

J Genet Genomics. Author manuscript; available in PMC 2020 Apr 25.

Published in final edited form as: J Genet Genomics. 2019 Apr 20; 46(4): 171–185. Published online 2019 Apr 25. doi: 10.1016/j.jgg.2019.03.011

PMCID:: PMC6553499

Abstract Article PDF–883K

Select item 653673117.

Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics

Sentiljana Gumeni, Zoi Evangelakou, Eleni N. Tsakiri, Luca Scorrano, Ioannis P. Trougakos

Redox Biol. 2019 Jun; 24: 101219. Published online 2019 May 17. doi: 10.1016/j.redox.2019.101219

PMCID:: PMC6536731

Abstract Article PDF–3.3M

Select item 650653918.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 639850119.

SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis

Kriti Chaplot, Lokesh Pimpale, Balaji Ramalingam, Senthilkumar Deivasigamani, Siddhesh S. Kamat, Girish S. Ratnaparkhi

Dis Model Mech. 2019 Feb 1; 12(2): dmm033803. Published online 2019 Feb 7. doi: 10.1242/dmm.033803

PMCID:: PMC6398501

Abstract Article

Select item 639570920.

Proteasome β5 subunit overexpression improves proteostasis during aging and extends lifespan in Drosophila melanogaster

Nga N. Nguyen, Anil Rana, Camille Goldman, Rhiannon Moore, Justin Tai, Yongchan Hong, Jingyi Shen, David W. Walker, Jae H. Hur

Sci Rep. 2019; 9: 3170. Published online 2019 Feb 28. doi: 10.1038/s41598-019-39508-4

PMCID:: PMC6395709

Abstract Article PDF–2.2M

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