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Select item 85949401.

Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts

Amrutha Kizhedathu, Piyush Chhajed, Lahari Yeramala, Deblina Sain Basu, Tina Mukherjee, Kutti R Vinothkumar, Arjun Guha

eLife. 2021; 10: e68636. Published online 2021 Oct 8. doi: 10.7554/eLife.68636

PMCID:: PMC8594940

Abstract Article PDF–3.0M

Select item 82197052.

The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang, Harun N. Noristani, Dan Li, Jingwen Niu, Shannon Trombley, Jessica I. Goldshteyn, Chuxi Wang, Shuchao Wang, Jingyun Qiu, Katarzyna Pogoda, Kalpana Mandal, Megan Brewster, Panteleimon Rompolas, Ye He, Paul A. Janmey, Gareth M. Thomas, Shuxin Li, Yuanquan Song

Nat Commun. 2021; 12: 3845. Published online 2021 Jun 22. doi: 10.1038/s41467-021-24131-7

PMCID:: PMC8219705

Abstract Article PDF–13M

Select item 80523433.

DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells

Lama Tarayrah-Ibraheim, Elital Chass Maurice, Guy Hadary, Sharon Ben-Hur, Alina Kolpakova, Tslil Braun, Yoav Peleg, Keren Yacobi-Sharon, Eli Arama

Nat Commun. 2021; 12: 2285. Published online 2021 Apr 16. doi: 10.1038/s41467-021-22622-1

PMCID:: PMC8052343

Abstract Article PDF–8.8M

Select item 78851204.

Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways

Amelia R. I. Lindsey, Tamanash Bhattacharya, Richard W. Hardy, Irene L. G. Newton

mBio. 2021 Jan-Feb; 12(1): e03472-20. Published online 2021 Feb 9. doi: 10.1128/mBio.03472-20

PMCID:: PMC7885120

Abstract Article PDF–3.5M

Select item 77290085.

Involvement of DNA Repair Genes and System of Radiation-Induced Activation of Transposons in Formation of Transgenerational Effects

Elena Yushkova

Front Genet. 2020; 11: 596947. Published online 2020 Nov 27. doi: 10.3389/fgene.2020.596947

PMCID:: PMC7729008

Abstract Article PDF–1.9M

Select item 60520236.

Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion

Anna Gorelick-Ashkenazi, Ron Weiss, Lena Sapozhnikov, Anat Florentin, Lama Tarayrah-Ibraheim, Dima Dweik, Keren Yacobi-Sharon, Eli Arama

Nat Commun. 2018; 9: 2806. Published online 2018 Jul 18. doi: 10.1038/s41467-018-05204-6

PMCID:: PMC6052023

Abstract Article PDF–9.2M

Select item 58112087.

Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells

Kevin L Lu, Jonathan O Nelson, George J Watase, Natalie Warsinger-Pepe, Yukiko M Yamashita

eLife. 2018; 7: e32421. Published online 2018 Feb 13. doi: 10.7554/eLife.32421

PMCID:: PMC5811208

Abstract Article PDF–5.5M

Select item 57078058.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890029.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 558637910.

DNA Replication Control During Drosophila Development: Insights into the Onset of S Phase, Replication Initiation, and Fork Progression

Brian L. Hua, Terry L. Orr-Weaver

Genetics. 2017 Sep; 207(1): 29–47. Published online 2017 Aug 31. doi: 10.1534/genetics.115.186627

PMCID:: PMC5586379

Abstract Article PDF–1.2M

Select item 557265111.

Drosophila histone demethylase KDM4A has enzymatic and non-enzymatic roles in controlling heterochromatin integrity

Serafin U. Colmenares, Joel M. Swenson, Sasha A. Langley, Cameron Kennedy, Sylvain V. Costes, Gary H. Karpen

Dev Cell. Author manuscript; available in PMC 2018 Jul 24.

Published in final edited form as: Dev Cell. 2017 Jul 24; 42(2): 156–169.e5. doi: 10.1016/j.devcel.2017.06.014

PMCID:: PMC5572651

Abstract Article PDF–1.3M

Select item 550014012.

Neutral Competition for Drosophila Follicle and Cyst Stem Cell Niches Requires Vesicle Trafficking Genes

Matthew S. Cook, Coralie Cazin, Marc Amoyel, Shinya Yamamoto, Erika Bach, Todd Nystul

Genetics. 2017 Jul; 206(3): 1417–1428. Published online 2017 May 16. doi: 10.1534/genetics.117.201202

PMCID:: PMC5500140

Abstract Article PDF–2.3M

Select item 543593613.

Initiation of Drosophila chorion gene amplification requires Claspin and mus101, whereas Claspin, but not mus101, plays a major role during elongation

Seung Ho Choi, Ji‐Hong Park, Tram Thi Ngoc Nguyen, Hee Jin Shim, Young‐Han Song

Dev Dyn. 2017 Jun; 246(6): 466–474. Published online 2017 Apr 11. doi: 10.1002/dvdy.24499

PMCID:: PMC5435936

Abstract Article PDF–837K

Select item 528983014.

DNA Repair in Drosophila: Mutagens, Models, and Missing Genes

Jeff Sekelsky

Genetics. 2017 Feb; 205(2): 471–490. Published online 2017 Jan 31. doi: 10.1534/genetics.116.186759

PMCID:: PMC5289830

Abstract Article PDF–891K

Select item 528532515.

Nuclear Dynamics of Heterochromatin Repair

Nuno Amaral, Taehyun Ryu, Xiao Li, Irene Chiolo

Trends Genet. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: Trends Genet. 2017 Feb; 33(2): 86–100. Published online 2017 Jan 16. doi: 10.1016/j.tig.2016.12.004

PMCID:: PMC5285325

Abstract Article PDF–854K

Select item 493323516.

The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation

Yu-tsung Shane Chen, Jianhong Wu, Paul Modrich, Tao-shih Hsieh

J Biol Chem. 2016 Jun 17; 291(25): 13216–13228. Published online 2016 Apr 27. doi: 10.1074/jbc.M116.721357

PMCID:: PMC4933235

Abstract Article PDF–1.5M

Select item 478080917.

The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster

Nicolas Svetec, Julie M. Cridland, Li Zhao, David J. Begun

PLoS Genet. 2016 Mar; 12(3): e1005869. Published online 2016 Mar 7. doi: 10.1371/journal.pgen.1005869

PMCID:: PMC4780809

Abstract Article PDF–543K

Select item 473800518.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 462858519.

Heterochromatic breaks move to the nuclear periphery to continue recombinational repair

Taehyun Ryu, Brett Spatola, Laetitia Delabaere, Katherine Bowlin, Hannah Hopp, Ryan Kunitake, Gary H. Karpen, Irene Chiolo

Nat Cell Biol. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Nat Cell Biol. 2015 Nov; 17(11): 1401–1411. Published online 2015 Oct 26. doi: 10.1038/ncb3258

PMCID:: PMC4628585

Abstract Article PDF–2.5M

Select item 458097320.

Replication fork progression during re-replication requires the DNA damage checkpoint and double-strand break repair

Jessica L. Alexander, M. Inmaculada Barrasa, Terry L. Orr-Weaver

Curr Biol. Author manuscript; available in PMC 2016 Jun 15.

Published in final edited form as: Curr Biol. 2015 Jun 15; 25(12): 1654–1660. Published online 2015 Jun 4. doi: 10.1016/j.cub.2015.04.058

PMCID:: PMC4580973

Abstract Article PDF–1.2M

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