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Select item 111379951.

Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma

Fei Xiong, Da Wang, Wei Xiong, Xin Wang, Wen-hua Huang, Guan-hua Wu, Wen-zheng Liu, Qi Wang, Jun-sheng Chen, Yi-yang Kuai, Bing Wang, Yong-jun Chen

J Exp Clin Cancer Res. 2024; 43: 152. Published online 2024 May 30. doi: 10.1186/s13046-024-03070-3

Correction in:: J Exp Clin Cancer Res. 2024; 43: 186.

PMCID:: PMC11137995

Abstract Article PDF–20M

Select item 109614282.

Attenuation of neuronal ferroptosis in intracerebral hemorrhage by inhibiting HDAC1/2: Microglial heterogenization via the Nrf2/HO1 pathway

Zhiwen Jiang, Heng Yang, Wei Ni, Xinjie Gao, Xu Pei, Hanqiang Jiang, Jiabin Su, Ruiyuan Weng, Yuchao Fei, Yanqin Gao, Yuxiang Gu

CNS Neurosci Ther. 2024 Mar; 30(3): e14646. Published online 2024 Mar 24. doi: 10.1111/cns.14646

PMCID:: PMC10961428

Abstract Article PDF–25M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108046254.

HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling

Michela Terri, Pilar Sandoval, Giulio Bontempi, Claudia Montaldo, Henar Tomero-Sanz, Valeria de Turris, Flavia Trionfetti, Lucía Pascual-Antón, Irene Clares-Pedrero, Cecilia Battistelli, Sergio Valente, Clemens Zwergel, Antonello Mai, Laura Rosanò, Miguel Ángel del Pozo, Miguel Sánchez-Álvarez, Carlos Cabañas, Marco Tripodi, Manuel López-Cabrera, Raffaele Strippoli

J Exp Clin Cancer Res. 2024; 43: 27. Published online 2024 Jan 23. doi: 10.1186/s13046-023-02930-8

PMCID:: PMC10804625

Abstract Article PDF–7.7M

Select item 105865155.

Histone deacetylase 1 regulates haloperidol-induced motor side effects in aged mice

Bryan M. McClarty, Saikat Chakraborty, Guadalupe Rodriguez, Hongxin Dong

Behav Brain Res. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Behav Brain Res. 2023 Jun 5; 447: 114420. Published online 2023 Apr 5. doi: 10.1016/j.bbr.2023.114420

PMCID:: PMC10586515

Abstract Article PDF–862K

Select item 104154066.

Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche

Hadas Sibony-Benyamini, Emil Aamar, David Enshell-Seijffers

Nat Commun. 2023; 14: 4820. Published online 2023 Aug 10. doi: 10.1038/s41467-023-40573-7

PMCID:: PMC10415406

Abstract Article PDF–26M

Select item 103348257.

RNF157 attenuates CD4⁺ T cell-mediated autoimmune response by promoting HDAC1 ubiquitination and degradation

Peng Wang, Jingjing Zhao, Yunke Tan, Junli Sheng, Shitong He, Yitian Chen, Dingnai Nie, Xiaolong You, Jinmei Luo, Yanling Zhang, Shengfeng Hu

Theranostics. 2023; 13(11): 3509–3523. Published online 2023 Jun 19. doi: 10.7150/thno.86307

PMCID:: PMC10334825

Abstract Article PDF–7.3M

Select item 101033118.

Cell Cycle and Senescence Regulation by Podocyte Histone Deacetylase 1 and 2

Paulina X. Medina Rangel, Elizabeth Cross, Chang Liu, Christopher E. Pedigo, Xuefei Tian, Elena Gutiérrez-Calabrés, Soichiro Nagata, Anupama Priyadarshini, Gabriel Lerner, Patricia Bunda, Sudhir Perincheri, Jianlei Gu, Hongyu Zhao, Ying Wang, Kazunori Inoue, Shuta Ishibe

J Am Soc Nephrol. 2023 Mar; 34(3): 433–450. Published online 2022 Nov 22. doi: 10.1681/ASN.2022050598

PMCID:: PMC10103311

Abstract Article

Select item 99090749.

Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons

Hong-Li Zheng, Shi-Yu Sun, Tong Jin, Ming Zhang, Ying Zeng, Qiaoqiao Liu, Kehui Yang, Runa Wei, Zhiqiang Pan, Fuqing Lin

Mol Pain. 2023; 19: 17448069231152125. Published online 2023 Feb 7. doi: 10.1177/17448069231152125

PMCID:: PMC9909074

Abstract Article PDF–2.2M

Select item 986459610.

5-Methylcytosine and 5-Hydroxymethylcytosine in Scrapie-Infected Sheep and Mouse Brain Tissues

Adelaida Hernaiz, Sara Sentre, Marina Betancor, Óscar López-Pérez, Mónica Salinas-Pena, Pilar Zaragoza, Juan José Badiola, Janne Markus Toivonen, Rosa Bolea, Inmaculada Martín-Burriel

Int J Mol Sci. 2023 Jan; 24(2): 1621. Published online 2023 Jan 13. doi: 10.3390/ijms24021621

PMCID:: PMC9864596

Abstract Article PDF–7.8M

Select item 960672211.

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development

Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener

Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.

Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002

PMCID:: PMC9606722

Abstract Article PDF–6.7M

Select item 956126012.

The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity

Jun Li, Chunming Cheng, Jinshu Xu, Ting Zhang, Bengu Tokat, Georgia Dolios, Aarthi Ramakrishnan, Li Shen, Rong Wang, Pin-Xian Xu

Nucleic Acids Res. 2022 Oct 14; 50(18): 10343–10359. Published online 2022 Sep 21. doi: 10.1093/nar/gkac760

PMCID:: PMC9561260

Abstract Article PDF–9.9M

Select item 937191413.

HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia

Sebastian Gregoricchio, Lélia Polit, Michela Esposito, Jérémy Berthelet, Laure Delestré, Emilie Evanno, M’Boyba Diop, Isabelle Gallais, Hanna Aleth, Mathilde Poplineau, Wilbert Zwart, Frank Rosenbauer, Fernando Rodrigues-Lima, Estelle Duprez, Valentina Boeva, Christel Guillouf

Nucleic Acids Res. 2022 Aug 12; 50(14): 7938–7958. Published online 2022 Jul 25. doi: 10.1093/nar/gkac613

PMCID:: PMC9371914

Abstract Article PDF–2.4M

Select item 936814214.

Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma

Maša Zrimšek, Hana Kuchaříková, Kristina Draganić, Pavlína Dobrovolná, Verena Heiss Spornberger, Lisa Winkelmayer, Melanie R. Hassler, Gabriela Lochmanová, Zbyněk Zdráhal, Gerda Egger

Cells. 2022 Aug; 11(15): 2380. Published online 2022 Aug 2. doi: 10.3390/cells11152380

PMCID:: PMC9368142

Abstract Article PDF–4.4M

Select item 879184515.

Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown

Kelly A. Hyndman, David K. Crossman

Physiol Genomics. 2022 Feb 1; 54(2): 45–57. Published online 2021 Dec 10. doi: 10.1152/physiolgenomics.00102.2021

PMCID:: PMC8791845

Abstract Article

Select item 876331716.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 868828617.

HDAC1/2 control proliferation and survival in adult epidermis and pre-basal cell carcinoma via p16 and p53

Xuming Zhu, Matthew Leboeuf, Fang Liu, Marina Grachtchouk, John T. Seykora, Edward E. Morrisey, Andrzej A. Dlugosz, Sarah E. Millar

J Invest Dermatol. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: J Invest Dermatol. 2022 Jan; 142(1): 77–87.e10. Published online 2021 Jul 18. doi: 10.1016/j.jid.2021.05.026

PMCID:: PMC8688286

Abstract Article PDF–1.3M

Select item 864073718.

BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos

Flavia Novelli, Angela Bononi, Qian Wang, Fang Bai, Simone Patergnani, Franz Kricek, Ellinor Haglund, Joelle S. Suarez, Mika Tanji, Ronghui Xu, Yasutaka Takanishi, Michael Minaai, Sandra Pastorino, Paul Morris, Greg Sakamoto, Harvey I. Pass, Haithem Barbour, Giovanni Gaudino, Carlotta Giorgi, Paolo Pinton, Jose N. Onuchic, Haining Yang, Michele Carbone

Proc Natl Acad Sci U S A. 2021 Nov 30; 118(48): e2111946118. Published online 2021 Nov 23. doi: 10.1073/pnas.2111946118

PMCID:: PMC8640737

Abstract Article PDF–2.5M

Select item 858089219.

Modulation of Placental Breast Cancer Resistance Protein by HDAC1 in Mice: Implications for Optimization of Pharmacotherapy During Pregnancy

Chuan Wang, Dan Ma, Yimin Hua, Hongyu Duan

Reprod Sci. 2021 Dec; 28(12): 3540–3546. Published online 2021 Oct 19. doi: 10.1007/s43032-021-00773-2

PMCID:: PMC8580892

Abstract Article PDF–4.6M

Select item 846405320.

HDAC1 is required for GATA-1 transcription activity, global chromatin occupancy and hematopoiesis

Bowen Yan, Jennifer Yang, Min Young Kim, Huacheng Luo, Nicholas Cesari, Tao Yang, John Strouboulis, Jiwang Zhang, Ross Hardison, Suming Huang, Yi Qiu

Nucleic Acids Res. 2021 Sep 27; 49(17): 9783–9798. Published online 2021 Aug 27. doi: 10.1093/nar/gkab737

PMCID:: PMC8464053

Abstract Article PDF–9.7M

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