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Select item 104998211.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 93485762.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 85529073.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 72374865.

SH3RF3 promotes breast cancer stem-like properties via JNK activation and PTX3 upregulation

Peiyuan Zhang, Yingjie Liu, Cheng Lian, Xuan Cao, Yuan Wang, Xiaoxun Li, Min Cong, Pu Tian, Xue Zhang, Gang Wei, Tong Liu, Guohong Hu

Nat Commun. 2020; 11: 2487. Published online 2020 May 19. doi: 10.1038/s41467-020-16051-9

PMCID:: PMC7237486

Abstract Article PDF–1.7M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 69812067.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 43809289.

Phospho-tyrosine dependent protein–protein interaction network

Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl

Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968

PMCID:: PMC4380928

Abstract Article PDF–1.9M

Select item 426638910.

FGF Homologous Factors and the Islet Brain-2 Scaffold Protein Regulate Activation of a Stress-Activated Protein Kinase

Jon Schoorlemmer, Mitchell Goldfarb

J Biol Chem. Author manuscript; available in PMC 2014 Dec 15.

Published in final edited form as: J Biol Chem. 2002 Dec 20; 277(51): 49111–49119. Published online 2002 Sep 18. doi: 10.1074/jbc.M205520200

PMCID:: PMC4266389

Abstract Article PDF–1.1M

Select item 392051111.

Evaluation of PKM2 and MAPK8IP2 Polymorphism in Ameloblastic Carcinoma: A Retrospective Quantitative Study

Abbas Khodayari, Seyyed Mohammad Hossein Ghaderian, Mohammad Jafarian, Alireza Jahangirnia, Alireza Nayebi, Fahimeh Akhlaghi, Nasim Taghavi, Reza Akbarzadeh Najar, Sanaz Tabarestani, Arash Khojasteh, Sarah Aghabozorg Afjeh

Int J Mol Cell Med. 2012 Autumn; 1(4): 203–209.

PMCID:: PMC3920511

Abstract Article PDF–66K

Select item 373366212.

Cerebellar and posterior fossa malformations in patients with autism-associated chromosome 22q13 terminal deletion

Kimberly A. Aldinger, Jillene Kogan, Virginia Kimonis, Bridget Fernandez, Denise Horn, Eva Klopocki, Brian Chung, Annick Toutain, Rosanna Weksberg, Kathleen J. Millen, A. James Barkovich, William B. Dobyns

Am J Med Genet A. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Am J Med Genet A. 2013 Jan; 0(1): 131–136. Published online 2012 Dec 7. doi: 10.1002/ajmg.a.35700

PMCID:: PMC3733662

Abstract Article PDF–1.8M

Select item 321648113.

Fibroblast Growth Factor Homologous Factors Are Intracellular Signalling Proteins

Jon Schoorlemmer, Mitchell Goldfarb

Curr Biol. Author manuscript; available in PMC 2011 Nov 15.

Published in final edited form as: Curr Biol. 2001 May 15; 11(10): 793–797. doi: 10.1016/s0960-9822(01)00232-9

PMCID:: PMC3216481

Abstract Article PDF–610K

Select item 320036714.

Behavioral and Cerebellar Transmission Deficits in Mice Lacking the Autism-Linked Gene Islet Brain-2

Joanna Giza, Michael J. Urbanski, Francesca Prestori, Bhaswati Bandyopadhyay, Annie Yam, Victor Friedrich, Kevin Kelley, Egidio D'Angelo, Mitchell Goldfarb

J Neurosci. 2010 Nov 3; 30(44): 14805–14816. doi: 10.1523/JNEUROSCI.1161-10.2010

PMCID:: PMC3200367

Abstract Article PDF–2.5M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 285923316.

LRRK2 and the Stress Response: Interaction with MKKs and JNK-Interacting Proteins

C.H. Hsu, D. Chan, B. Wolozin

Neurodegener Dis. 2010 Apr; 7(1-3): 68–75. Published online 2010 Feb 18. doi: 10.1159/000285509

PMCID:: PMC2859233

Abstract Article PDF–241K

Select item 224301717.

Modulation of Interleukin-1 Transcriptional Response by the Interaction between VRK2 and the JIP1 Scaffold Protein

Sandra Blanco, Marta Sanz-García, Claudio R. Santos, Pedro A. Lazo

PLoS One. 2008; 3(2): e1660. Published online 2008 Feb 20. doi: 10.1371/journal.pone.0001660

PMCID:: PMC2243017

Abstract Article PDF–1016K

Select item 217156618.

Coordinated transport of phosphorylated amyloid-β precursor protein and c-Jun NH₂-terminal kinase–interacting protein-1

Zoia Muresan, Virgil Muresan

J Cell Biol. 2005 Nov 21; 171(4): 615–625. doi: 10.1083/jcb.200502043

PMCID:: PMC2171566

Abstract Article PDF–2.6M

Select item 208407419.

Regular Article: Interaction of ASK1 and the β-Amyloid Precursor Protein in a Stress-Signaling Complex

Veronica Galvan, Surita Banwait, Patricia Spilman, Olivia F. Gorostiza, Alyson Peel, Danielle Crippen, Gurleen Sidhu, Hidenori Ichijo, Dale E. Bredesen

Neurobiol Dis. Author manuscript; available in PMC 2008 Oct 1.

Published in final edited form as: Neurobiol Dis. 2007 Oct; 28(1): 65–75. Published online 2007 Jul 3. doi: 10.1016/j.nbd.2007.06.017

PMCID:: PMC2084074

Abstract Article PDF–1.7M

Select item 138356320.

A unique set of SH3–SH3 interactions controls IB1 homodimerization

Ole Kristensen, Sylvie Guenat, Imran Dar, Nathalie Allaman-Pillet, Amar Abderrahmani, Mourad Ferdaoussi, Raphaël Roduit, Fabienne Maurer, Jacques S Beckmann, Jette S Kastrup, Michael Gajhede, Christophe Bonny

EMBO J. 2006 Feb 22; 25(4): 785–797. Published online 2006 Feb 2. doi: 10.1038/sj.emboj.7600982

PMCID:: PMC1383563

Abstract Article PDF–674K

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