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Select item 111589771.

Interaction of antiproliferative protein Tob with the CCR4‐NOT deadenylase complex

Takashi Miyasaka, Masahiro Morita, Kentaro Ito, Toru Suzuki, Hiroyuki Fukuda, Shizu Takeda, Jun‐Ichiro Inoue, Kentaro Semba, Tadashi Yamamoto

Cancer Sci. 2008 Apr; 99(4): 755–761. Published online 2008 Mar 28. doi: 10.1111/j.1349-7006.2008.00746.x

PMCID:: PMC11158977

Abstract Article PDF–210K

Select item 110106402.

TOB1 modulates neutrophil phenotypes to influence gastric cancer progression and immunotherapy efficacy

Jinfeng Zhang, Yunlong Li, Jing Chen, Tongtong Huang, Jing Lin, Yilin Pi, Huiting Hao, Dong Wang, Xiao Liang, Songbin Fu, Jingcui Yu

Front Immunol. 2024; 15: 1369087. Published online 2024 Mar 28. doi: 10.3389/fimmu.2024.1369087

PMCID:: PMC11010640

Abstract Article PDF–4.5M

Select item 98231313.

Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth

David J. Wisniewski, Mariya S. Liyasova, Soumya Korrapati, Xu Zhang, Shashikala Ratnayake, Qingrong Chen, Samuel F. Gilbert, Alexis Catalano, Donna Voeller, Daoud Meerzaman, Udayan Guha, Natalie Porat-Shliom, Christina M. Annunziata, Stanley Lipkowitz

J Biol Chem. 2023 Jan; 299(1): 102766. Published online 2022 Dec 5. doi: 10.1016/j.jbc.2022.102766

PMCID:: PMC9823131

Abstract Article PDF–2.5M

Select item 88202124.

Involvement of TOB1 on autophagy in gastric cancer AGS cells via decreasing the activation of AKT/mTOR signaling pathway

Dong Wang, Yunlong Li, Shuning Sui, Mengdi Cai, Kexian Dong, Ping Wang, Xiao Liang, Songbin Fu, Jingcui Yu

PeerJ. 2022; 10: e12904. Published online 2022 Feb 4. doi: 10.7717/peerj.12904

PMCID:: PMC8820212

Abstract Article PDF–7.2M

Select item 87690725.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80254647.

Identification of miR-25-3p as a tumor biomarker: Regulation of cellular functions via TOB1 in breast cancer

Tianyi Zhao, Wenjing Meng, Yenlie Chin, Lili Gao, Xiyue Yang, Shuangyu Sun, Xingfang Pan, Lihong He

Mol Med Rep. 2021 Jun; 23(6): 406. Published online 2021 Mar 26. doi: 10.3892/mmr.2021.12045

PMCID:: PMC8025464

Abstract Article PDF–2.3M

Select item 70130738.

TOB1 suppresses proliferation in K‐Ras wild‐type pancreatic cancer

Yuru Bai, Lu Qiao, Ning Xie, Yan Li, Yongzhan Nie, Yan Pan, Yupeng Shi, Jinhai Wang, Na Liu

Cancer Med. 2020 Feb; 9(4): 1503–1514. Published online 2019 Dec 31. doi: 10.1002/cam4.2756

PMCID:: PMC7013073

Abstract Article PDF–2.1M

Select item 67426469.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 624028710.

High expression of Tob1 indicates poor survival outcome and promotes tumour progression via a Wnt positive feedback loop in colon cancer

Dandan Li, Li Xiao, Yuetan Ge, Yu Fu, Wenqing Zhang, Hanwei Cao, Binbin Chen, Haibin Wang, Yan-yan Zhan, Tianhui Hu

Mol Cancer. 2018; 17: 159. Published online 2018 Nov 17. doi: 10.1186/s12943-018-0907-9

PMCID:: PMC6240287

Abstract Article PDF–3.2M

Select item 592675311.

Association of ANA, a Member of the Antiproliferative Tob Family Proteins, with a Cafl Component of the CCR4 Transcriptional Regulatory Complex

Yutaka Yoshida, Eri Hosoda, Takahisa Nakamura, Tadashi Yamamoto

Jpn J Cancer Res. 2001 Jun; 92(6): 592–596. doi: 10.1111/j.1349-7006.2001.tb01135.x

PMCID:: PMC5926753

Summary PDF–1.6M

Select item 583609712.

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration

Ella Fung, Carmen Richter, Hong‐Bin Yang, Isabell Schäffer, Roman Fischer, Benedikt M Kessler, Florian Bassermann, Vincenzo D'Angiolella

EMBO Rep. 2018 Mar; 19(3): e44799. Published online 2018 Jan 18. doi: 10.15252/embr.201744799

PMCID:: PMC5836097

Abstract Article PDF–1.9M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 471212414.

Acquisition of Estrogen Independence Induces TOB1-Related Mechanisms Supporting Breast Cancer Cell Proliferation

Yong-Wei Zhang, Rochelle E. Nasto, Rency Varghese, Sandra A. Jablonski, Ilya G Serebriiskii, Rishi Surana, Valerie S. Calvert, Ionut Bebu, Joseph Murray, Lu Jin, Michael Johnson, Rebecca Riggins, Habtom Ressom, Emmanuel Petricoin, III, Robert Clarke, Erica A. Golemis, Louis M. Weiner

Oncogene. Author manuscript; available in PMC 2016 Mar 31.

Published in final edited form as: Oncogene. 2016 Mar 31; 35(13): 1643–1656. Published online 2015 Jul 13. doi: 10.1038/onc.2015.226

PMCID:: PMC4712124

Abstract Article PDF–1.0M

Select item 461721115.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 401032816.

Suppression of human lung cancer cell proliferation and metastasis in vitro by the transducer of ErbB-2.1 (TOB1)

Yang Jiao, Ke-kang Sun, Lin Zhao, Jia-ying Xu, Li-li Wang, Sai-jun Fan

Acta Pharmacol Sin. 2012 Feb; 33(2): 250–260. Published online 2011 Dec 12. doi: 10.1038/aps.2011.163

PMCID:: PMC4010328

Abstract Article PDF–3.4M

Select item 385546017.

Identification of Novel Subregions of LOH in Gastric Cancer and Analysis of the HIC1 and TOB1 Tumor Suppressor Genes in These Subregions

Jingcui Yu, Peng Liu, Xiaobo Cui, Yu Sui, Guohua Ji, Rongwei Guan, Donglin Sun, Wei Ji, Fangli Liu, An Liu, Yuzhen Zhao, Yang Yu, Yan Jin, Jing Bai, Jingshu Geng, Yingwei Xue, Jiping Qi, Ki-Young Lee, Songbin Fu

Mol Cells. 2011 Jul 31; 32(1): 47–55. doi: 10.1007/s10059-011-2316-4

PMCID:: PMC3855460

Abstract Article PDF–886K

Select item 358275918.

Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting β-catenin signaling

JUTHIKA KUNDU, S.M. RIAJUL WAHAB, JOYDEB KUMAR KUNDU, YOON-LA CHOI, OZGUR CEM ERKIN, HUN SEOK LEE, SANG GYU PARK, YOUNG KEE SHIN

Int J Oncol. 2012 Sep; 41(3): 839–848. Published online 2012 Jun 12. doi: 10.3892/ijo.2012.1517

PMCID:: PMC3582759

Abstract Article PDF–1.0M

Select item 354626319.

Comparative analysis of virus-host interactomes with a mammalian high- throughput protein complementation assay based on Gaussia princeps luciferase

Grégory Neveu, Patricia Cassonnet, Pierre-Olivier Vidalain, Caroline Rolloy, José Mendoza, Louis Jones, Frédéric Tangy, Mandy Muller, Caroline Demeret, Lionel Tafforeau, Vincent Lotteau, Chantal Rabourdin-Combe, Gilles Travé, Amélie Dricot, David E. Hill, Marc Vidal, Michel Favre, Yves Jacob

Methods. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Methods. 2012 Dec; 58(4): 349–359. Published online 2012 Aug 8. doi: 10.1016/j.ymeth.2012.07.029

PMCID:: PMC3546263

Abstract Article PDF–4.3M

Select item 351745620.

The Anti-Proliferative Activity of BTG/TOB Proteins Is Mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) Deadenylase Subunits of the Ccr4-Not Complex

Rachel Doidge, Saloni Mittal, Akhmed Aslam, G. Sebastiaan Winkler

PLoS One. 2012; 7(12): e51331. Published online 2012 Dec 7. doi: 10.1371/journal.pone.0051331

PMCID:: PMC3517456

Abstract Article PDF–1.0M

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