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Select item 113988661.

Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation

Jiansen Lu, Jiahuan Zhang, Huaji Jiang, Zhiqiang Hu, Yufen Zhang, Lian He, Jianwu Yang, Yingchao Xie, Dan Wu, Hongyu Li, Ke Zeng, Peng Tan, Qingyue Xiao, Zijing Song, Chenglong Pan, Xiaochun Bai, Xiao Yu

eLife. 2024; 12: RP87935. Published online 2024 Sep 13. doi: 10.7554/eLife.87935

PMCID:: PMC11398866

Abstract Article PDF–7.8M

Select item 106539942.

EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8

Yinghua Zhao, Liyan Sui, Ping Wu, Letian Li, Li Liu, Baohua Ma, Wenfang Wang, Hongmiao Chi, Ze-Dong Wang, Zhengkai Wei, Zhijun Hou, Kaiyu Zhang, Junqi Niu, Ningyi Jin, Chang Li, Jixue Zhao, Guoqing Wang, Quan Liu

J Virol. 2023 Oct; 97(10): e01028-23. Published online 2023 Sep 29. doi: 10.1128/jvi.01028-23

PMCID:: PMC10653994

Abstract Article PDF–4.2M

Select item 105427553.

Crotonylated BEX2 interacts with NDP52 and enhances mitophagy to modulate chemotherapeutic agent-induced apoptosis in non-small-cell lung cancer cells

Ning Mu, Yu Wang, Xiaopeng Li, Zhiyuan Du, Yingdi Wu, Min Su, Yingying Wang, Xiaoyang Sun, Ling Su, Xiangguo Liu

Cell Death Dis. 2023 Sep; 14(9): 645. Published online 2023 Sep 30. doi: 10.1038/s41419-023-06164-6

PMCID:: PMC10542755

Abstract Article PDF–8.2M

Select item 103514484.

N protein of PEDV plays chess game with host proteins by selective autophagy

Xueying Zhai, Ning Kong, Yu Zhang, Yiyi Song, Wenzhen Qin, Xinyu Yang, Chenqian Ye, Manqing Ye, Wu Tong, Changlong Liu, Hao Zheng, Hai Yu, Wen Zhang, Xia Yang, Gaiping Zhang, Guangzhi Tong, Tongling Shan

Autophagy. 2023; 19(8): 2338–2352. Published online 2023 Mar 2. doi: 10.1080/15548627.2023.2181615

PMCID:: PMC10351448

Abstract Article PDF–3.9M

Select item 102896485.

VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation

Zhiqiang Hu, Yingchao Xie, Jiansen Lu, Jianwu Yang, Jiahuan Zhang, Huaji Jiang, Hongyu Li, Yufeng Zhang, Dan Wu, Ke Zeng, Xiaochun Bai, Xiao Yu

Sci Adv. 2023 Jun; 9(25): eadg2339. Published online 2023 Jun 23. doi: 10.1126/sciadv.adg2339

PMCID:: PMC10289648

Abstract Article PDF–2.6M

Select item 102834406.

Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules

Cuiwei Yang, Zhangshun Wang, Yingjin Kang, Qianqian Yi, Tong Wang, Yun Bai, Yanfen Liu

Autophagy. 2023; 19(7): 1934–1951. Published online 2023 Jan 24. doi: 10.1080/15548627.2022.2164427

PMCID:: PMC10283440

Abstract Article PDF–5.2M

Select item 102834217.

Copper-dependent autophagic degradation of GPX4 drives ferroptosis

Qian Xue, Ding Yan, Xi Chen, Xiaofen Li, Rui Kang, Daniel J. Klionsky, Guido Kroemer, Xin Chen, Daolin Tang, Jinbao Liu

Autophagy. 2023; 19(7): 1982–1996. Published online 2023 Jan 12. doi: 10.1080/15548627.2023.2165323

PMCID:: PMC10283421

Abstract Article PDF–4.1M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101122819.

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1

François Le Guerroué, Eric N Bunker, William M Rosencrans, Jack T Nguyen, Mohammed A Basar, Achim Werner, Tsui-Fen Chou, Chunxin Wang, Richard J Youle

Mol Cell. Author manuscript; available in PMC 2024 Mar 16.

Published in final edited form as: Mol Cell. 2023 Mar 16; 83(6): 927–941.e8. Published online 2023 Mar 9. doi: 10.1016/j.molcel.2023.02.023

PMCID:: PMC10112281

Abstract Article PDF–2.4M

Select item 1007290610.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 1001295711.

NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2)

Jiawei Hao, Jinqian Li, Zhenzhen Zhang, Yang Yang, Qing Zhou, Tiantian Wu, Tongling Chen, Zhongdao Wu, Ping Zhang, Jun Cui, Yi-Ping Li

Autophagy. 2023; 19(4): 1332–1347. Published online 2022 Sep 29. doi: 10.1080/15548627.2022.2126614

PMCID:: PMC10012957

Abstract Article PDF–3.8M

Select item 997593912.

NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy

Tetsushi Kataura, Elsje G Otten, Yoana Rabanal‐Ruiz, Elias Adriaenssens, Francesca Urselli, Filippo Scialo, Lanyu Fan, Graham R Smith, William M Dawson, Xingxiang Chen, Wyatt W Yue, Agnieszka K Bronowska, Bernadette Carroll, Sascha Martens, Michael Lazarou, Viktor I Korolchuk

EMBO J. 2023 Mar; 42(5): e111372. Published online 2022 Dec 14. doi: 10.15252/embj.2022111372

PMCID:: PMC9975939

Abstract Article PDF–5.2M

Select item 968299613.

hnRNP K Degrades Viral Nucleocapsid Protein and Induces Type I IFN Production to Inhibit Porcine Epidemic Diarrhea Virus Replication

Wenzhen Qin, Ning Kong, Chunmei Wang, Sujie Dong, Huanjie Zhai, Xueying Zhai, Xinyu Yang, Chenqian Ye, Manqing Ye, Wu Tong, Changlong Liu, Lingxue Yu, Hao Zheng, Hai Yu, Daoliang Lan, Wen Zhang, Guangzhi Tong, Tongling Shan

J Virol. 2022 Nov; 96(22): e01555-22. Published online 2022 Nov 1. doi: 10.1128/jvi.01555-22

PMCID:: PMC9682996

Abstract Article PDF–2.8M

Select item 954241514.

OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity

Weihong Xie, Shuo Tian, Jiahui Yang, Sihui Cai, Shouheng Jin, Tao Zhou, Yaoxing Wu, Zhiyun Chen, Yanqin Ji, Jun Cui

Autophagy. 2022; 18(10): 2288–2302. Published online 2022 Jan 31. doi: 10.1080/15548627.2022.2026098

PMCID:: PMC9542415

Abstract Article PDF–3.2M

Select item 948160215.

Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function

Simon Maria Kienle, Tobias Schneider, Katrin Stuber, Christoph Globisch, Jasmin Jansen, Florian Stengel, Christine Peter, Andreas Marx, Michael Kovermann, Martin Scheffner

Nat Commun. 2022; 13: 5435. Published online 2022 Sep 16. doi: 10.1038/s41467-022-33087-1

PMCID:: PMC9481602

Abstract Article PDF–3.7M

Select item 927928516.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 927815417.

FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon

Sujie Dong, Ning Kong, Chunmei Wang, Youwen Li, Dage Sun, Wenzhen Qin, Huanjie Zhai, Xueying Zhai, Xinyu Yang, Chenqian Ye, Manqing Ye, Changlong Liu, Lingxue Yu, Hao Zheng, Wu Tong, Hai Yu, Wen Zhang, Guangzhi Tong, Tongling Shan

J Virol. 2022 Jul; 96(13): e00618-22. Published online 2022 Jun 13. doi: 10.1128/jvi.00618-22

PMCID:: PMC9278154

Abstract Article PDF–4.0M

Select item 919674718.

Global Proximity Interactome of the Human Macroautophagy Pathway

Yi Xin (Iris) Tu, Andrew M. Sydor, Etienne Coyaud, Estelle M. N. Laurent, Diana Dyer, Nora Mellouk, Jonathan St-Germain, Robert M. Vernon, Julie D. Forman-Kay, Taoyingnan Li, Rong Hua, Kexin Zhao, Neale D. Ridgway, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(5): 1174–1186. Published online 2021 Sep 15. doi: 10.1080/15548627.2021.1965711

PMCID:: PMC9196747

Abstract Article PDF–3.1M

Select item 917759919.

ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-κB

Minho Won, Kyeong Ah Park, Sup Kim, Eunjin Ju, Youngbok Ko, Heonjong Yoo, Hyunju Ro, Jaeseob Lee, Junseo Oh, Eun Gyo Lee, Sang Yean Kim, Suk Woo Nam, Han-Ming Shen, Min-Kyung Yeo, Jin Man Kim, Gang Min Hur

Cell Death Differ. 2022 Jun; 29(6): 1152–1163. Published online 2021 Nov 27. doi: 10.1038/s41418-021-00906-9

PMCID:: PMC9177599

Abstract Article PDF–3.4M

Select item 910523520.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151