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Select item 86644861.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 83851542.

Quantitative Proteomic and Metabolomic Profiling Reveals Altered Mitochondrial Metabolism and Folate Biosynthesis Pathways in the Aging Drosophila Eye

Hana Hall, Bruce R. Cooper, Guihong Qi, Aruna B. Wijeratne, Amber L. Mosley, Vikki M. Weake

Mol Cell Proteomics. 2021; 20: 100127. Published online 2021 Jul 29. doi: 10.1016/j.mcpro.2021.100127

PMCID:: PMC8385154

Abstract Article PDF–3.7M

Select item 61565393.

Proper splicing contributes to visual function in the aging Drosophila eye

Rachel Stegeman, Hana Hall, Spencer E. Escobedo, Henry C. Chang, Vikki M. Weake

Aging Cell. 2018 Oct; 17(5): e12817. Published online 2018 Jul 12. doi: 10.1111/acel.12817

PMCID:: PMC6156539

Abstract Article PDF–1.2M

Select item 60524634.

Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity

Siming Ma, Andrei S. Avanesov, Emily Porter, Byung Cheon Lee, Marco Mariotti, Nadezhda Zemskaya, Roderic Guigo, Alexey A. Moskalev, Vadim N. Gladyshev

Aging Cell. 2018 Aug; 17(4): e12740. Published online 2018 Apr 19. doi: 10.1111/acel.12740

PMCID:: PMC6052463

Abstract Article PDF–1.3M

Select item 59891575.

An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio

Wei-Hsiang Lin, Miaomiao He, Yuen Ngan Fan, Richard A. Baines

J Neurogenet. 2018; 32(2): 106–117. Published online 2018 May 2. doi: 10.1080/01677063.2018.1465570

PMCID:: PMC5989157

Abstract Article PDF–1.5M

Select item 57286866.

The output of protein-coding genes shifts to circular RNAs when the pre-mRNA processing machinery is limiting

Dongming Liang, Deirdre C. Tatomer, Zheng Luo, Huang Wu, Li Yang, Ling-Ling Chen, Sara Cherry, Jeremy E. Wilusz

Mol Cell. Author manuscript; available in PMC 2018 Dec 7.

Published in final edited form as: Mol Cell. 2017 Dec 7; 68(5): 940–954.e3. Published online 2017 Nov 22. doi: 10.1016/j.molcel.2017.10.034

PMCID:: PMC5728686

Abstract Article PDF–3.1M

Select item 57078057.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890028.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 53120049.

Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis

Wei-Hsiang Lin, Carlo N. G. Giachello, Richard A. Baines

Dis Model Mech. 2017 Feb 1; 10(2): 141–150. doi: 10.1242/dmm.027045

PMCID:: PMC5312004

Abstract Article

Select item 503306110.

An integrative analysis of the InR/PI3K/Akt network identifies the dynamic response to Insulin signaling

Arunachalam Vinayagam, Meghana M. Kulkarni, Richelle Sopko, Xiaoyun Sun, Yanhui Hu, Ankita Nand, Christians Villalta, Ahmadali Moghimi, Xuemei Yang, Stephanie E. Mohr, Pengyu Hong, John Asara, Norbert Perrimon

Cell Rep. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Cell Rep. 2016 Sep 13; 16(11): 3062–3074. doi: 10.1016/j.celrep.2016.08.029

PMCID:: PMC5033061

Abstract Article PDF–3.3M

Select item 473800511.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 470597912.

The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub

Pak N. Kwong, Michael Chambers, Ajay A. Vashisht, Wiam Turki-Judeh, Tak Yu Yau, James A. Wohlschlegel, Albert J. Courey

J Biol Chem. 2015 Dec 11; 290(50): 30119–30130. Published online 2015 Oct 19. doi: 10.1074/jbc.M115.681171

Correction in:: J Biol Chem. 2016 Mar 25; 291(13): 6784.

PMCID:: PMC4705979

Abstract Article PDF–1.3M

Select item 457717813.

spenito is required for sex determination in Drosophila melanogaster

Dong Yan, Norbert Perrimon

Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37): 11606–11611. Published online 2015 Aug 31. doi: 10.1073/pnas.1515891112

PMCID:: PMC4577178

Abstract Article PDF–1.9M

Select item 452833014.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832915.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435288716.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 427152717.

Phylostratigraphic Bias Creates Spurious Patterns of Genome Evolution

Bryan A. Moyers, Jianzhi Zhang

Mol Biol Evol. 2015 Jan 1; 32(1): 258–267. Published online 2014 Oct 13. doi: 10.1093/molbev/msu286

Correction in:: Mol Biol Evol. 2016 Nov; 33(11): 3031.

PMCID:: PMC4271527

Abstract Article PDF–618K

Select item 423277118.

A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis

Senthilkumar Deivasigamani, Hemant Kumar Verma, Ryu Ueda, Anuradha Ratnaparkhi, Girish S. Ratnaparkhi

Biol Open. 2014 Nov 15; 3(11): 1127–1138. Published online 2014 Oct 31. doi: 10.1242/bio.201410066

PMCID:: PMC4232771

Abstract Article PDF–1.0M

Select item 395833419.

A Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila

Dariel Ashton-Beaucage, Christian M. Udell, Patrick Gendron, Malha Sahmi, Martin Lefrançois, Caroline Baril, Anne-Sophie Guenier, Jean Duchaine, Daniel Lamarre, Sébastien Lemieux, Marc Therrien

PLoS Biol. 2014 Mar; 12(3): e1001809. Published online 2014 Mar 18. doi: 10.1371/journal.pbio.1001809

PMCID:: PMC3958334

Abstract Article PDF–4.0M

Select item 353067720.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

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