PMC Links for GEO Profiles (Select 9782540) - PMC

Enric Ureña, Bowen Xu, Jennifer C. Regan, Magda L. Atilano, Lucy J. Minkley, Danny Filer, Yu-Xuan Lu, Ekin Bolukbasi, Mobina Khericha, Nazif Alic, Linda Partridge

Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4): e2311313121. Published online 2024 Jan 19. doi: 10.1073/pnas.2311313121

PMCID:: PMC10823232

Abstract Article PDF–814K

Select item 106476824.

Signaling Pathways Controlling Axonal Wrapping in Drosophila

Marie Baldenius, Steffen Kautzmann, Suchet Nanda, Christian Klämbt

Cells. 2023 Nov; 12(21): 2553. Published online 2023 Oct 31. doi: 10.3390/cells12212553

PMCID:: PMC10647682

Abstract Article PDF–4.3M

Select item 104506725.

Evolutionary history of MEK1 illuminates the nature of deleterious mutations

Ekaterina P. Andrianova, Robert A. Marmion, Stanislav Y. Shvartsman, Igor B. Zhulin

Proc Natl Acad Sci U S A. 2023 Aug 22; 120(34): e2304184120. Published online 2023 Aug 14. doi: 10.1073/pnas.2304184120

PMCID:: PMC10450672

Abstract Article PDF–3.7M

Select item 102809286.

Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS

Wenkai Yue, Xue Deng, Zhao Wang, Mingsheng Jiang, Rirong Hu, Yongjia Duan, Qiangqiang Wang, Jihong Cui, Yanshan Fang

Immun Ageing. 2023; 20: 27. Published online 2023 Jun 20. doi: 10.1186/s12979-023-00354-8

PMCID:: PMC10280928

Abstract Article PDF–9.0M

Select item 101514087.

A targeted genetic modifier screen in Drosophila uncovers vulnerabilities in a genetically complex model of colon cancer

Ishwaree Datta, Tajah Vassel, Benjamin Linkous, Tyler Odum, Christian Drew, Andrew Taylor, Erdem Bangi

G3 (Bethesda) 2023 May; 13(5): jkad053. Published online 2023 Mar 6. doi: 10.1093/g3journal/jkad053

PMCID:: PMC10151408

Abstract Article PDF–785K

Select item 101170808.

EGFR Signaling Activates Intestinal Stem Cells by Promoting Mitochondrial Biogenesis and β-oxidation

Chenge Zhang, Yinhua Jin, Marco Marchetti, Mitchell R. Lewis, Omar T. Hammouda, Bruce A. Edgar

Curr Biol. Author manuscript; available in PMC 2023 Sep 12.

Published in final edited form as: Curr Biol. 2022 Sep 12; 32(17): 3704–3719.e7. Published online 2022 Jul 26. doi: 10.1016/j.cub.2022.07.003

PMCID:: PMC10117080

Abstract Article PDF–3.9M

Select item 101104029.

A Drosophila chemical screen reveals synergistic effect of MEK and DGKα inhibition in Ras-driven cancer

John E. La Marca, Robert W. Ely, Sarah T. Diepstraten, Peter Burke, Gemma L. Kelly, Patrick O. Humbert, Helena E. Richardson

Dis Model Mech. 2023 Mar 1; 16(3): dmm049769. Published online 2023 Apr 3. doi: 10.1242/dmm.049769

PMCID:: PMC10110402

Abstract Article

Select item 1002669710.

STOCHASTIC PHENOTYPES IN RAS-DEPENDENT DEVELOPMENTAL DISEASES

Robert A. Marmion, Alison G. Simpkins, Lena A. Barrett, David W. Denberg, Susan Zusman, Jodi Schottenfeld-Roames, Trudi Schüpbach, Stanislav Y. Shvartsman

Curr Biol. Author manuscript; available in PMC 2024 Mar 13.

Published in final edited form as: Curr Biol. 2023 Mar 13; 33(5): 807–816.e4. Published online 2023 Jan 26. doi: 10.1016/j.cub.2023.01.008

PMCID:: PMC10026697

Abstract Article PDF–2.2M

Select item 949265211.

Regulation of oocyte maturation: Role of conserved ERK signaling

Debabrata Das, Swathi Arur

Mol Reprod Dev. Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Mol Reprod Dev. 2022 Jul 31 : 10.1002/mrd.23637. Published online 2022 Jul 31. doi: 10.1002/mrd.23637

PMCID:: PMC9492652

Abstract Article PDF–2.5M

Select item 947454512.

Mettl3-dependent m⁶A modification attenuates the brain stress response in Drosophila

Alexandra E. Perlegos, Emily J. Shields, Hui Shen, Kathy Fange Liu, Nancy M. Bonini

Nat Commun. 2022; 13: 5387. Published online 2022 Sep 14. doi: 10.1038/s41467-022-33085-3

PMCID:: PMC9474545

Abstract Article PDF–2.7M

Select item 913365313.

Auxilin regulates intestinal stem cell proliferation through EGFR

Hang Zhao, Xuejing Ren, Ruiyan Kong, Lin Shi, Zhengran Li, Runqi Wang, Rui Ma, Huiqing Zhao, Fuli Liu, Henry C. Chang, Chun-Hong Chen, Zhouhua Li

Stem Cell Reports. 2022 May 10; 17(5): 1120–1137. Published online 2022 Apr 14. doi: 10.1016/j.stemcr.2022.03.010

PMCID:: PMC9133653

Abstract Article PDF–7.1M

Select item 883299714.

The Yun/Prohibitin complex regulates adult Drosophila intestinal stem cell proliferation through the transcription factor E2F1

Hang Zhao, Lin Shi, Zhengran Li, Ruiyan Kong, Xuejing Ren, Rui Ma, Lemei Jia, Meifang Ma, Shan Lu, Ran Xu, Richard Binari, Jian-Hua Wang, Meng-qiu Dong, Norbert Perrimon, Zhouhua Li

Proc Natl Acad Sci U S A. 2022 Feb 8; 119(6): e2111711119. Published online 2022 Feb 3. doi: 10.1073/pnas.2111711119

PMCID:: PMC8832997

Abstract Article PDF–4.4M

Select item 879554015.

Translational control of E2f1 regulates the Drosophila cell cycle

Jan Inge Øvrebø, Mary-Rose Bradley-Gill, Norman Zielke, Minhee Kim, Marco Marchetti, Jonathan Bohlen, Megan Lewis, Monique van Straaten, Nam-Sung Moon, Bruce A. Edgar

Proc Natl Acad Sci U S A. 2022 Jan 25; 119(4): e2113704119. Published online 2022 Jan 24. doi: 10.1073/pnas.2113704119

PMCID:: PMC8795540

Abstract Article PDF–11M

Select item 866983416.

Tumor–host interactions through the lens of Drosophila

David Bilder, Katy Ong, Tsai-Ching Hsi, Kavya Adiga, Jung Kim

Nat Rev Cancer. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nat Rev Cancer. 2021 Nov; 21(11): 687–700. Published online 2021 Aug 13. doi: 10.1038/s41568-021-00387-5

PMCID:: PMC8669834

Abstract Article PDF–385K

Select item 866448617.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349