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Items: 1 to 20 of 42

1.
Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway
Kevin Alicea-Torres, Emilio Sanseviero, Jun Gui, Jinyun Chen, Filippo Veglia, Qiujin Yu, Laxminarasimha Donthireddy, Andrew Kossenkov, Cindy Lin, Shuyu Fu, Charles Mulligan, Brian Nam, Gregory Masters, Fred Denstman, Joseph Bennett, Neil Hockstein, Agnieszka Rynda-Apple, Yulia Nefedova, Serge Y. Fuchs, Dmitry I. Gabrilovich
Nat Commun. 2021; 12: 1717. Published online 2021 Mar 19. doi: 10.1038/s41467-021-22033-2
PMCID:
PMC7979850
AbstractArticlePDF–1.0M
2.
Interferon Receptor Trafficking and Signaling: Journey to the Cross Roads
Natacha Zanin, Christine Viaris de Lesegno, Christophe Lamaze, Cedric M. Blouin
Front Immunol. 2020; 11: 615603. Published online 2021 Jan 20. doi: 10.3389/fimmu.2020.615603
PMCID:
PMC7855707
AbstractArticlePDF–2.0M
3.
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
Rajendra Karki, Bhesh Raj Sharma, Shraddha Tuladhar, Evan Peter Williams, Lillian Zalduondo, Parimal Samir, Min Zheng, Balamurugan Sundaram, Balaji Banoth, R.K. Subbarao Malireddi, Patrick Schreiner, Geoffrey Neale, Peter Vogel, Richard Webby, Colleen Beth Jonsson, Thirumala-Devi Kanneganti
Cell. 2021 Jan 7; 184(1): 149–168.e17. Published online 2020 Nov 19. doi: 10.1016/j.cell.2020.11.025
PMCID:
PMC7674074
AbstractArticlePDF–9.9M
4.
Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion
David E. Place, Benoit Briard, Parimal Samir, Rajendra Karki, Anannya Bhattacharya, Clifford S. Guy, Jennifer L. Peters, Sharon Frase, Peter Vogel, Geoffrey Neale, Masahiro Yamamoto, Thirumala-Devi Kanneganti
PLoS Pathog. 2020 Mar; 16(3): e1008364. Published online 2020 Mar 9. doi: 10.1371/journal.ppat.1008364
PMCID:
PMC7082077
AbstractArticlePDF–6.9M
5.
IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections
Kelly M. Shepardson, Kyle Larson, Laura L. Johns, Kayla Stanek, Hanbyul Cho, Julia Wellham, Haley Henderson, Agnieszka Rynda-Apple
Front Immunol. 2018; 9: 2589. Published online 2018 Nov 9. doi: 10.3389/fimmu.2018.02589
PMCID:
PMC6237881
AbstractArticlePDF–1.9M
6.
Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection
Qifan Zhu, Si Ming Man, Rajendra Karki, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti
Cell Rep. Author manuscript; available in PMC 2018 Oct 28.
Published in final edited form as: Cell Rep. 2018 Mar 20; 22(12): 3168–3174. doi: 10.1016/j.celrep.2018.02.096
PMCID:
PMC6204211
AbstractArticlePDF–1.6M
7.
Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice
Javier A. Carrero, Nicholas D. Benshoff, Kimberly Nalley, Emil R. Unanue
Diabetes. 2018 Sep; 67(9): 1830–1835. Published online 2018 Jul 3. doi: 10.2337/db18-0331
PMCID:
PMC6110319
AbstractArticlePDF–1.6M
8.
IRF8 regulates transcription of Naips for NLRC4 inflammasome activation
Rajendra Karki, Ein Lee, David Place, Parimal Samir, Jayadev Mavuluri, Bhesh Raj Sharma, Arjun Balakrishnan, R. K. Subbarao Malireddi, Rechel Geiger, Qifan Zhu, Geoffrey Neale, Thirumala-Devi Kanneganti
Cell. Author manuscript; available in PMC 2019 May 3.
Published in final edited form as: Cell. 2018 May 3; 173(4): 920–933.e13. Published online 2018 Mar 22. doi: 10.1016/j.cell.2018.02.055
PMCID:
PMC5935577
AbstractArticlePDF–2.0M
9.
Distinct regulatory mechanisms control proinflammatory cytokines IL-18 and IL-1β
Qifan Zhu, Thirumala-Devi Kannegant
J Immunol. Author manuscript; available in PMC 2018 Jun 1.
Published in final edited form as: J Immunol. 2017 Jun 1; 198(11): 4210–4215. Published online 2017 May 3. doi: 10.4049/jimmunol.1700352
PMCID:
PMC5544497
AbstractArticlePDF–569K
10.
SYK licenses MyD88 to instigate IL-1α-mediated inflammatory disease
Prajwal Gurung, Gaofeng Fan, John R. Lukens, Peter Vogel, Nicholas K Tonks, Thirumala-Devi Kanneganti
Immunity. Author manuscript; available in PMC 2018 Apr 18.
Published in final edited form as: Immunity. 2017 Apr 18; 46(4): 635–648. Published online 2017 Apr 11. doi: 10.1016/j.immuni.2017.03.014
PMCID:
PMC5501252
AbstractArticlePDF–1.1M
11.
The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity
Yichuan Xiao, Qiang Zou, Xiaoping Xie, Ting Liu, Haiyan S. Li, Zuliang Jie, Jin Jin, Hongbo Hu, Ganiraju Manyam, Li Zhang, Xuhong Cheng, Hui Wang, Isabelle Marie, David E. Levy, Stephanie S. Watowich, Shao-Cong Sun
J Exp Med. 2017 May 1; 214(5): 1493–1507. doi: 10.1084/jem.20161524
PMCID:
PMC5413337
AbstractArticlePDF–3.4M
12.
Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects
Elena Bekerman, Gregory Neveu, Ana Shulla, Jennifer Brannan, Szu-Yuan Pu, Stanley Wang, Fei Xiao, Rina Barouch-Bentov, Russell R. Bakken, Roberto Mateo, Jennifer Govero, Claude M. Nagamine, Michael S. Diamond, Steven De Jonghe, Piet Herdewijn, John M. Dye, Glenn Randall, Shirit Einav
J Clin Invest. 2017 Apr 3; 127(4): 1338–1352. Published online 2017 Feb 27. doi: 10.1172/JCI89857
PMCID:
PMC5373883
AbstractArticlePDF–1.6M
13.
A Mouse Model of Zika Virus Sexual Transmission and Vaginal Viral Replication
William Weihao Tang, Matthew Perry Young, Anila Mamidi, Jose Angel Regla-Nava, Kenneth Kim, Sujan Shresta
Cell Rep. Author manuscript; available in PMC 2017 Dec 20.
Published in final edited form as: Cell Rep. 2016 Dec 20; 17(12): 3091–3098. doi: 10.1016/j.celrep.2016.11.070
PMCID:
PMC5193244
AbstractArticlePDF–1.0M
14.
ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways
Teneema Kuriakose, Si Ming Man, R.K. Subbarao Malireddi, Rajendra Karki, Sannula Kesavardhana, David E. Place, Geoffrey Neale, Peter Vogel, Thirumala-Devi Kanneganti
Sci Immunol. Author manuscript; available in PMC 2016 Dec 1.
Published in final edited form as: Sci Immunol. 2016 Aug 5; 1(2): aag2045. Published online 2016 Aug 12. doi: 10.1126/sciimmunol.aag2045
PMCID:
PMC5131924
AbstractArticlePDF–2.2M
15.
Interferon alpha inhibits spinal cord synaptic and nociceptive transmission via neuronal-glial interactions
Chien-Cheng Liu, Yong-Jing Gao, Hao Luo, Temugin Berta, Zhen-Zhong Xu, Ru-Rong Ji, Ping-Heng Tan
Sci Rep. 2016; 6: 34356. Published online 2016 Sep 27. doi: 10.1038/srep34356
PMCID:
PMC5037469
AbstractArticlePDF–2.2M
16.
B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6
Shaun W. Jackson, Holly M. Jacobs, Tanvi Arkatkar, Elizabeth M. Dam, Nicole E. Scharping, Nikita S. Kolhatkar, Baidong Hou, Jane H. Buckner, David J. Rawlings
J Exp Med. 2016 May 2; 213(5): 733–750. doi: 10.1084/jem.20151724
PMCID:
PMC4854732
AbstractArticlePDF–3.5M
17.
Development of Th17-associated interstitial kidney inflammation in lupus-prone mice lacking the gene encoding Signal Transduction and Activator of Transcription-1 (STAT-1)
Gloria Yiu, Tue Kruse Rasmussen, Bahareh Ajami, David J. Haddon, Alvina D. Chu, Stephanie Tangsombatvisit, Winston A. Haynes, Vivian Diep, Larry Steinman, James Faix, Paul J. Utz
Arthritis Rheumatol. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: Arthritis Rheumatol. 2016 May; 68(5): 1233–1244. doi: 10.1002/art.39535
PMCID:
PMC4848130
AbstractArticlePDF–3.1M
18.
Interferon γ (IFNγ) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses
Barbara Kroczynska, Robert L. Rafidi, Beata Majchrzak-Kita, Ewa M. Kosciuczuk, Gavin T. Blyth, Jacek Jemielity, Zofia Warminska, Diana Saleiro, Swarna Mehrotra, Ahmet Dirim Arslan, Eleanor N. Fish, Leonidas C. Platanias
J Biol Chem. 2016 Jan 29; 291(5): 2389–2396. Published online 2015 Dec 8. doi: 10.1074/jbc.M115.664995
PMCID:
PMC4732221
AbstractArticlePDF–1.0M
19.
TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN
Burcu Temizoz, Etsushi Kuroda, Keiichi Ohata, Nao Jounai, Koji Ozasa, Kouji Kobiyama, Taiki Aoshi, Ken J Ishii
Eur J Immunol. 2015 Apr; 45(4): 1159–1169. Published online 2015 Feb 5. doi: 10.1002/eji.201445132
PMCID:
PMC4671267
AbstractArticlePDF–893K
20.
Hydroxypropyl-β-Cyclodextrin Spikes Local Inflammation That Induces Th2 Cell and T Follicular Helper Cell Responses to the Coadministered Antigen
Motoyasu Onishi, Koji Ozasa, Kouji Kobiyama, Keiichi Ohata, Mitsutaka Kitano, Keiichi Taniguchi, Tomoyuki Homma, Masanori Kobayashi, Akihiko Sato, Yuko Katakai, Yasuhiro Yasutomi, Edward Wijaya, Yoshinobu Igarashi, Noriyuki Nakatsu, Wataru Ise, Takeshi Inoue, Hiroshi Yamada, Alexis Vandenbon, Daron M. Standley, Tomohiro Kurosaki, Cevayir Coban, Taiki Aoshi, Etsushi Kuroda, Ken J. Ishii
J Immunol. 2015 Mar 15; 194(6): 2673–2682. Published online 2015 Feb 13. doi: 10.4049/jimmunol.1402027
PMCID:
PMC4470223
AbstractArticlePDF–1.5M

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