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Select item 114465481.

The zinc-finger transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay

Moran Kelbert, Antonio Jordán-Pla, Lola de Miguel-Jiménez, José García-Martínez, Michael Selitrennik, Adi Guterman, Noa Henig, Sander Granneman, José E Pérez-Ortín, Sebastián Chávez, Mordechai Choder

eLife. 2024; 12: RP90766. Published online 2024 Oct 2. doi: 10.7554/eLife.90766

PMCID:: PMC11446548

Abstract Article PDF–7.1M

Select item 112445262.

N-terminal acetylation of Set1-COMPASS fine-tunes H3K4 methylation patterns

Hyeonju Woo, Junsoo Oh, Yong-Joon Cho, Goo Taeg Oh, Seon-Young Kim, Kisoon Dan, Dohyun Han, Jung-Shin Lee, TaeSoo Kim

Sci Adv. 2024 Jul 12; 10(28): eadl6280. Published online 2024 Jul 12. doi: 10.1126/sciadv.adl6280

PMCID:: PMC11244526

Abstract Article PDF–10M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105517004.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 102333685.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 92098116.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 62654577.

Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation

Jongcheol Jeon, Robert K McGinty, Tom W Muir, Jung-Ae Kim, Jaehoon Kim

Nucleic Acids Res. 2018 Nov 30; 46(21): 11129–11143. Published online 2018 Oct 16. doi: 10.1093/nar/gky920

PMCID:: PMC6265457

Abstract Article PDF–3.8M

Select item 62587108.

Architecture and subunit arrangement of the complete Saccharomyces cerevisiae COMPASS complex

Yanxing Wang, Zhanyu Ding, Xiangyang Liu, Yu Bao, Min Huang, Catherine C. L. Wong, Xiaoyu Hong, Yao Cong

Sci Rep. 2018; 8: 17405. Published online 2018 Nov 27. doi: 10.1038/s41598-018-35609-8

PMCID:: PMC6258710

Abstract Article PDF–2.2M

Select item 62162779.

A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export

Paula Oliete‐Calvo, Joan Serrano‐Quílez, Carme Nuño‐Cabanes, María E Pérez‐Martínez, Luis M Soares, Bernhard Dichtl, Stephen Buratowski, José E Pérez‐Ortín, Susana Rodríguez‐Navarro

EMBO Rep. 2018 Nov; 19(11): e45992. Published online 2018 Sep 24. doi: 10.15252/embr.201845992

PMCID:: PMC6216277

Abstract Article PDF–1.7M

Select item 621571310.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

Select item 610893611.

Structure and conformational dynamics of a COMPASS histone H3K4 methyltransferase complex

Qianhui Qu, Yohhei Takahashi, Yidai Yang, Hongli Hu, Yan Zhang, Joseph S. Brunzelle, Jean-Francois Couture, Ali Shilatifard, Georgios Skiniotis

Cell. Author manuscript; available in PMC 2019 Aug 23.

Published in final edited form as: Cell. 2018 Aug 23; 174(5): 1117–1126.e12. Published online 2018 Aug 9. doi: 10.1016/j.cell.2018.07.020

PMCID:: PMC6108936

Abstract Article PDF–1.2M

Select item 592252812.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen

PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319

PMCID:: PMC5922528

Abstract Article PDF–7.1M

Select item 582852913.

The PHD finger protein Spp1 has distinct functions in the Set1 and the meiotic DSB formation complexes

Céline Adam, Raphaël Guérois, Anna Citarella, Laura Verardi, Florine Adolphe, Claire Béneut, Vérane Sommermeyer, Claire Ramus, Jérôme Govin, Yohann Couté, Valérie Borde

PLoS Genet. 2018 Feb; 14(2): e1007223. Published online 2018 Feb 14. doi: 10.1371/journal.pgen.1007223

PMCID:: PMC5828529

Abstract Article PDF–4.5M

Select item 576535914.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 566188515.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 560025416.

The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823

PMCID:: PMC5600254

Abstract Article PDF–2.4M

Select item 520434817.

A novel translational control mechanism involving RNA structures within coding sequences

Jennifer Jungfleisch, Danny D. Nedialkova, Ivan Dotu, Katherine E. Sloan, Neus Martinez-Bosch, Lukas Brüning, Emanuele Raineri, Pilar Navarro, Markus T. Bohnsack, Sebastian A. Leidel, Juana Díez

Genome Res. 2017 Jan; 27(1): 95–106. doi: 10.1101/gr.209015.116

Correction in:: Genome Res. 2017 Apr; 27(4): 663.

PMCID:: PMC5204348

Abstract Article PDF–1.3M

Select item 488883918.

Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2

Andria Schibler, Evangelia Koutelou, Junya Tomida, Marenda Wilson-Pham, Li Wang, Yue Lu, Alexa Parra Cabrera, Renee J. Chosed, Wenqian Li, Bing Li, Xiaobing Shi, Richard D. Wood, Sharon Y.R. Dent

Genes Dev. 2016 May 15; 30(10): 1187–1197. doi: 10.1101/gad.278887.116

PMCID:: PMC4888839

Abstract Article PDF–685K

Select item 461603919.

Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p

Christopher J. Kershaw, Joseph L. Costello, David Talavera, William Rowe, Lydia M. Castelli, Paul F. G. Sims, Christopher M. Grant, Mark P. Ashe, Simon J. Hubbard, Graham D. Pavitt

Sci Rep. 2015; 5: 15518. Published online 2015 Oct 23. doi: 10.1038/srep15518

PMCID:: PMC4616039

Abstract Article PDF–2.2M

Select item 438922920.

Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control

Irene Gallina, Camilla Colding, Peter Henriksen, Petra Beli, Kyosuke Nakamura, Judith Offman, David P. Mathiasen, Sonia Silva, Eva Hoffmann, Anja Groth, Chunaram Choudhary, Michael Lisby

Nat Commun. 2015 Mar 30; 6: 6533. Published online 2015 Mar 30. doi: 10.1038/ncomms7533

PMCID:: PMC4389229

Abstract Article PDF–3.1M

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