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Items: 1 to 20 of 106

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
Wilma Tixi, Maricela Maldonado, Ya-Ting Chang, Amy Chiu, Wilson Yeung, Nazia Parveen, Michael S Nelson, Ryan Hart, Shihao Wang, Wu Jih Hsu, Patrick Fueger, Janel L Kopp, Mark O Huising, Sangeeta Dhawan, Hung Ping Shih
eLife. 2023; 12: e90006. Published online 2023 Aug 23. doi: 10.7554/eLife.90006
PMCID:
PMC10482429
AbstractArticlePDF–26M
3.
Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain
Vladimir Abarinov, Joshua A. Levine, Angela J. Churchill, Bryce Hopwood, Cailin S. Deiter, Michelle A. Guney, Kristen L. Wells, Jessica M. Schrunk, Yuchun Guo, Jennifer Hammelman, David K. Gifford, Mark A. Magnuson, Hynek Wichterle, Lori Sussel
Genes Dev. 2023 Jun 1; 37(11-12): 490–504. doi: 10.1101/gad.350569.123
PMCID:
PMC10393193
AbstractArticlePDF–22M
4.
ISL1 controls pancreatic alpha cell fate and beta cell maturation
Romana Bohuslavova, Valeria Fabriciova, Laura Lebrón-Mora, Jessica Malfatti, Ondrej Smolik, Lukas Valihrach, Sarka Benesova, Daniel Zucha, Zuzana Berkova, Frantisek Saudek, Sylvia M Evans, Gabriela Pavlinkova
Cell Biosci. 2023; 13: 53. Published online 2023 Mar 10. doi: 10.1186/s13578-023-01003-9
PMCID:
PMC9999528
AbstractArticlePDF–7.7M
5.
Adult pancreatic islet endocrine cells emerge as fetal hormone-expressing cells
Marta Perez-Frances, Maria Valentina Abate, Delphine Baronnier, Philipp E. Scherer, Yoshio Fujitani, Fabrizio Thorel, Pedro L. Herrera
Cell Rep. 2022 Feb 15; 38(7): 110377. Published online 2022 Feb 15. doi: 10.1016/j.celrep.2022.110377
PMCID:
PMC8864465
AbstractArticle
6.
Gfi1 Loss Protects against Two Models of Induced Diabetes
Tiziana Napolitano, Fabio Avolio, Serena Silvano, Sara Forcisi, Anja Pfeifer, Andhira Vieira, Sergi Navarro-Sanz, Marika Elsa Friano, Chaïma Ayachi, Anna Garrido-Utrilla, Josipa Atlija, Biljana Hadzic, Jérôme Becam, Anette Sousa-De-Veiga, Magali Dodille Plaisant, Shruti Balaji, Didier F. Pisani, Magali Mondin, Philippe Schmitt-Kopplin, Ez-Zoubir Amri, Patrick Collombat
Cells. 2021 Nov; 10(11): 2805. Published online 2021 Oct 20. doi: 10.3390/cells10112805
PMCID:
PMC8616283
AbstractArticlePDF–11M
7.
Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs
Karrie D Dudek, Anna B Osipovich, Jean-Philippe Cartailler, Guoquing Gu, Mark A Magnuson
G3 (Bethesda) 2021 Nov; 11(11): jkab303. Published online 2021 Aug 26. doi: 10.1093/g3journal/jkab303
PMCID:
PMC8527475
AbstractArticlePDF–1.2M
8.
Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production
Marta Perez-Frances, Léon van Gurp, Maria Valentina Abate, Valentina Cigliola, Kenichiro Furuyama, Eva Bru-Tari, Daniel Oropeza, Taïna Carreaux, Yoshio Fujitani, Fabrizio Thorel, Pedro L. Herrera
Nat Commun. 2021; 12: 4458. Published online 2021 Jul 22. doi: 10.1038/s41467-021-24788-0
Correction in:
Nat Commun. 2021; 12: 5783.
PMCID:
PMC8298494
AbstractArticlePDF–11M
9.
NEUROD1 Is Required for the Early α and β Endocrine Differentiation in the Pancreas
Romana Bohuslavova, Ondrej Smolik, Jessica Malfatti, Zuzana Berkova, Zaneta Novakova, Frantisek Saudek, Gabriela Pavlinkova
Int J Mol Sci. 2021 Jul; 22(13): 6713. Published online 2021 Jun 23. doi: 10.3390/ijms22136713
PMCID:
PMC8268837
AbstractArticlePDF–4.9M
10.
A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development
Anna B. Osipovich, Karrie D. Dudek, Emily Greenfest-Allen, Jean-Philippe Cartailler, Elisabetta Manduchi, Leah Potter Case, Eunyoung Choi, Austin G. Chapman, Hannah W. Clayton, Guoqiang Gu, Christian J. Stoeckert, Jr, Mark A. Magnuson
Development. 2021 Mar 15; 148(6): dev196964. Published online 2021 Mar 22. doi: 10.1242/dev.196964
PMCID:
PMC8015253
AbstractArticle
11.
Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas
Alexandra Theis, Ruth A. Singer, Diana Garofalo, Alexander Paul, Anila Narayana, Lori Sussel
Development. 2021 Mar 15; 148(6): dev192401. Published online 2021 Mar 24. doi: 10.1242/dev.192401
PMCID:
PMC8015241
AbstractArticle
12.
LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development
Nicholas K. Vinckier, Nisha A. Patel, Ryan J. Geusz, Allen Wang, Jinzhao Wang, Ileana Matta, Austin R. Harrington, Matthew Wortham, Nichole Wetton, Jianxun Wang, Ulupi S. Jhala, Michael G. Rosenfeld, Christopher W. Benner, Hung-Ping Shih, Maike Sander
Nat Commun. 2020; 11: 2082. Published online 2020 Apr 29. doi: 10.1038/s41467-020-16017-x
PMCID:
PMC7190832
AbstractArticlePDF–3.5M
13.
Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production
Julie Piccand, Constance Vagne, Florence Blot, Aline Meunier, Anthony Beucher, Perrine Strasser, Mari L. Lund, Sabitri Ghimire, Laure Nivlet, Céline Lapp, Natalia Petersen, Maja S. Engelstoft, Christelle Thibault-Carpentier, Céline Keime, Sara Jimenez Correa, Valérie Schreiber, Nacho Molina, Thue W. Schwartz, Adèle De Arcangelis, Gérard Gradwohl
Mol Metab. 2019 Nov; 29: 24–39. Published online 2019 Aug 13. doi: 10.1016/j.molmet.2019.08.007
PMCID:
PMC6728766
AbstractArticlePDF–3.3M
14.
Neurog3-independent methylation is the earliest detectable mark distinguishing pancreatic progenitor identity
Jing Liu, Amrita Banerjee, Charles A. Herring, Jonathan Attalla, Ruiying Hu, Yanwen Xu, Qiujia Shao, Alan J. Simmons, Prasanna K. Dadi, Sui Wang, David A. Jacobson, Bindong Liu, Emily Hodges, Ken S. Lau, Guoqiang Gu
Dev Cell. Author manuscript; available in PMC 2020 Jan 7.
Published in final edited form as: Dev Cell. 2019 Jan 7; 48(1): 49–63.e7. doi: 10.1016/j.devcel.2018.11.048
PMCID:
PMC6327977
AbstractArticlePDF–4.1M
15.
Lineage dynamics of murine pancreatic development at single-cell resolution
Lauren E. Byrnes, Daniel M. Wong, Meena Subramaniam, Nathaniel P. Meyer, Caroline L. Gilchrist, Sarah M. Knox, Aaron D. Tward, Chun J. Ye, Julie B. Sneddon
Nat Commun. 2018; 9: 3922. Published online 2018 Sep 25. doi: 10.1038/s41467-018-06176-3
PMCID:
PMC6156586
AbstractArticlePDF–15M
16.
Expression and functional studies of the GDNF family receptor-alpha3 (GFRα3) in the pancreas
Laure Nivlet, Joel Herrmann, Delia Esteban Martin, Aline Meunier, Christophe Orvain, Gérard Gradwohl
J Mol Endocrinol. Author manuscript; available in PMC 2018 Apr 23.
Published in final edited form as: J Mol Endocrinol. 2016 Feb; 56(2): 77–90. Published online 2015 Nov 17. doi: 10.1530/JME-15-0213
PMCID:
PMC5911917
AbstractArticlePDF–3.0M
17.
Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets
Katie L. Sinagoga, William J. Stone, Jacqueline V. Schiesser, Jamie I. Schweitzer, Leesa Sampson, Yi Zheng, James M. Wells
Development. 2017 Jul 1; 144(13): 2402–2414. doi: 10.1242/dev.146316
PMCID:
PMC5536865
AbstractArticle
18.
Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation
Roberta Azzarelli, Christopher Hurley, Magdalena K. Sznurkowska, Steffen Rulands, Laura Hardwick, Ivonne Gamper, Fahad Ali, Laura McCracken, Christopher Hindley, Fiona McDuff, Sonia Nestorowa, Richard Kemp, Kenneth Jones, Berthold Göttgens, Meritxell Huch, Gerard Evan, Benjamin D. Simons, Douglas Winton, Anna Philpott
Dev Cell. 2017 May 8; 41(3): 274–286.e5. doi: 10.1016/j.devcel.2017.04.004
PMCID:
PMC5425251
AbstractArticlePDF–3.5M
19.
Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development
Angela J Churchill, Giselle Dominguez Gutiérrez, Ruth A Singer, David S Lorberbaum, Kevin A Fischer, Lori Sussel
eLife. 2017; 6: e20010. Published online 2017 Jan 10. doi: 10.7554/eLife.20010
PMCID:
PMC5224921
AbstractArticlePDF–1.9M
20.
Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development
Hisayoshi Omori, Soichiro Ogaki, Daisuke Sakano, Mutsumi Sato, Kahoko Umeda, Naoki Takeda, Naomi Nakagata, Shoen Kume
FEBS Lett. 2016 Aug; 590(16): 2584–2593. Published online 2016 Jul 14. doi: 10.1002/1873-3468.12271
PMCID:
PMC5129588
AbstractArticlePDF–1.4M

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