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Items: 1 to 20 of 40

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-κB/cyclin D1 pathway
Lin Mei, Yun-Min Zheng, Tengyao Song, Vishal R. Yadav, Leroy C. Joseph, Lillian Truong, Sharath Kandhi, Margarida M. Barroso, Hiroshi Takeshima, Marc A. Judson, Yong-Xiao Wang
Nat Commun. 2020; 11: 3527. Published online 2020 Jul 15. doi: 10.1038/s41467-020-17314-1
PMCID:
PMC7363799
AbstractArticlePDF–1.5M
3.
Role of lateral amygdala calstabin2 in regulation of fear memory
Ren-wen Han, Zhi-peng Liu, Hong-ru Lin, Ao-wen Tian, Yun-fei Xiao, Jie Wei, Ke-yu Deng, Bing-xing Pan, Hong-bo Xin
Mol Brain. 2020; 13: 35. Published online 2020 Mar 9. doi: 10.1186/s13041-020-00576-7
PMCID:
PMC7063811
AbstractArticlePDF–933K
4.
FKBP12.6 protects heart from AngII‐induced hypertrophy through inhibiting Ca2+/calmodulin‐mediated signalling pathways in vivo and in vitro
Yun‐Fei Xiao, Zhi‐Xiong Zeng, Xiao‐Hui Guan, Ling‐Fang Wang, Chan‐Juan Wang, Huidong Shi, Weinian Shou, Ke‐Yu Deng, Hong‐Bo Xin
J Cell Mol Med. 2018 Jul; 22(7): 3638–3651. Published online 2018 Apr 22. doi: 10.1111/jcmm.13645
PMCID:
PMC6010737
AbstractArticlePDF–2.9M
5.
Sensitized signalling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes
Yan-Ting Zhao, Yun-Bo Guo, Lei Gu, Xue-Xin Fan, Hua-Qian Yang, Zheng Chen, Peng Zhou, Qi Yuan, Guang-Ju Ji, Shi-Qiang Wang
Cardiovasc Res. 2017 Mar; 113(3): 332–342. Published online 2017 Jan 10. doi: 10.1093/cvr/cvw247
PMCID:
PMC5852519
AbstractArticlePDF–1.4M
6.
Calstabin 2: An important regulator for learning and memory in mice
Qi Yuan, Ke-Yu Deng, Le Sun, Shaopeng Chi, Zhiguang Yang, Jun Wang, Hong-Bo Xin, Xiaoqun Wang, Guangju Ji
Sci Rep. 2016; 6: 21087. Published online 2016 Feb 18. doi: 10.1038/srep21087
PMCID:
PMC4758079
AbstractArticlePDF–1.5M
7.
Functional Role of Calstabin2 in Age-related Cardiac Alterations
Qi Yuan, Zheng Chen, Gaetano Santulli, Lei Gu, Zhi-Guang Yang, Zeng-Qiang Yuan, Yan-Ting Zhao, Hong-Bo Xin, Ke-Yu Deng, Shi-Qiang Wang, Guangju Ji
Sci Rep. 2014; 4: 7425. Published online 2014 Dec 11. doi: 10.1038/srep07425
PMCID:
PMC4262885
AbstractArticlePDF–1.6M
8.
Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice
Wei Wang, Andrew P. Landstrom, Qiongling Wang, Michelle L. Munro, David Beavers, Michael J. Ackerman, Christian Soeller, Xander H. T. Wehrens
Am J Physiol Heart Circ Physiol. 2014 Nov 1; 307(9): H1317–H1326. Published online 2014 Sep 5. doi: 10.1152/ajpheart.00413.2014
Correction in:
Am J Physiol Heart Circ Physiol. 2018 May 1; 314(5): H1115.
PMCID:
PMC4217007
AbstractArticle
9.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
10.
Sirolimus-FKBP12.6 Impairs Endothelial Barrier Function through PKCα Activation and Disruption of the p120-VE Cadherin Interaction
Anwer Habib, Vinit Karmali, Rohini Polavarapu, Hirokuni Akahori, Qi Cheng, Kim Pachura, Frank D. Kolodgie, Aloke V. Finn
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Oct; 33(10): 10.1161/ATVBAHA.113.301659. Published online 2013 Jul 25. doi: 10.1161/ATVBAHA.113.301659
PMCID:
PMC3827918
AbstractArticlePDF–2.6M
11.
Calcium Leak Through Ryanodine Receptors Leads To Atrial Fibrillation In Three Mouse Models of Catecholaminergic Polymorphic Ventricular Tachycardia
Jian Shan, Wenjun Xie, Matthew Betzenhauser, Steven Reiken, Bi-Xing Chen, Anetta Wronska, Andrew R. Marks
Circ Res. Author manuscript; available in PMC 2013 Aug 31.
Published in final edited form as: Circ Res. 2012 Aug 31; 111(6): 708–717. Published online 2012 Jul 24. doi: 10.1161/CIRCRESAHA.112.273342
PMCID:
PMC3734386
AbstractArticlePDF–4.4M
12.
Role of Leaky Neuronal Ryanodine Receptors in Stress-Induced Cognitive Dysfunction
Xiaoping Liu, Matthew J. Betzenhauser, Steve Reiken, Albano C. Meli, Wenjun Xie, Bi-Xing Chen, Ottavio Arancio, Andrew R. Marks
Cell. Author manuscript; available in PMC 2013 Aug 31.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 1055–1067. doi: 10.1016/j.cell.2012.06.052
PMCID:
PMC3690518
AbstractArticlePDF–2.7M
13.
The Role of FK506-Binding Proteins 12 and 12.6 in Regulating Cardiac Function
Bai-Yan Li, Hanying Chen, Mitsunori Maruyama, Wenjun Zhang, Jin Zhang, Zhen-Wei Pan, Michael Rubart, Peng-Sheng Chen, Weinian Shou
Pediatr Cardiol. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: Pediatr Cardiol. 2012 Aug; 33(6): 988–994. Published online 2012 Mar 30. doi: 10.1007/s00246-012-0298-4
PMCID:
PMC3582179
AbstractArticlePDF–1.2M
14.
A Mutation in the Srrm4 Gene Causes Alternative Splicing Defects and Deafness in the Bronx Waltzer Mouse
Yoko Nakano, Israt Jahan, Gregory Bonde, Xingshen Sun, Michael S. Hildebrand, John F. Engelhardt, Richard J. H. Smith, Robert A. Cornell, Bernd Fritzsch, Botond Bánfi
PLoS Genet. 2012 Oct; 8(10): e1002966. Published online 2012 Oct 4. doi: 10.1371/journal.pgen.1002966
PMCID:
PMC3464207
AbstractArticlePDF–4.1M
15.
Transcription factor CHF1/Hey2 regulates EC coupling and heart failure in mice through regulation of FKBP12.6
Yonggang Liu, F. Steven Korte, Farid Moussavi-Harami, Man Yu, Maria Razumova, Michael Regnier, Michael T. Chin
Am J Physiol Heart Circ Physiol. 2012 May 1; 302(9): H1860–H1870. Published online 2012 Mar 9. doi: 10.1152/ajpheart.00702.2011
PMCID:
PMC3362059
AbstractArticle
16.
Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module
Matthew Koss, Alexandre Bolze, Andrea Brendolan, Matilde Saggese, Terence D. Capellini, Ekaterina Bojilova, Bertrand Boisson, Owen W.J. Prall, David Elliott, Mark Solloway, Elisa Lenti, Chisa Hidaka, Ching-Pin Chang, Nizar Mahlaoui, Richard P. Harvey, Jean-Laurent Casanova, Licia Selleri
Dev Cell. Author manuscript; available in PMC 2013 May 15.
Published in final edited form as: Dev Cell. 2012 May 15; 22(5): 913–926. Published online 2012 May 3. doi: 10.1016/j.devcel.2012.02.009
PMCID:
PMC3356505
AbstractArticlePDF–6.8M
17.
Inhibition of CaMKII Phosphorylation of RyR2 Prevents Induction of Atrial Fibrillation in FKBP12.6 knock-out Mice
Na Li, Tiannan Wang, Wei Wang, Michael J. Culter, Qiongling Wang, Niels Voigt, David S. Rosenbaum, Dobromir Dobrev, Xander H.T. Wehrens
Circ Res. Author manuscript; available in PMC 2013 Feb 3.
Published in final edited form as: Circ Res. 2012 Feb 3; 110(3): 465–470. Published online 2011 Dec 8. doi: 10.1161/CIRCRESAHA.111.253229
PMCID:
PMC3272138
AbstractArticlePDF–783K
18.
Transgenic Analysis of the Role of FKBP12.6 in Cardiac Function and Intracellular Calcium Release
Ying Liu, Hanying Chen, Guangju Ji, Baiyan Li, Peter J. Mohler, Zhiming Zhu, Weidong Yong, Zhuang Chen, Xuehong Xu, Hongbo Xin, Weinian Shou
Assay Drug Dev Technol. 2011 Dec; 9(6): 620–627. doi: 10.1089/adt.2011.0411
PMCID:
PMC3232634
AbstractArticlePDF–528K
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion
Jérémy Fauconnier, Albano C. Meli, Jérôme Thireau, Stephanie Roberge, Jian Shan, Yassine Sassi, Steven R. Reiken, Jean-Michel Rauzier, Alexandre Marchand, David Chauvier, Cécile Cassan, Christine Crozier, Patrice Bideaux, Anne-Marie Lompré, Etienne Jacotot, Andrew R. Marks, Alain Lacampagne
Proc Natl Acad Sci U S A. 2011 Aug 9; 108(32): 13258–13263. Published online 2011 Jul 25. doi: 10.1073/pnas.1100286108
PMCID:
PMC3156220
AbstractArticlePDF–758K

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