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Items: 1 to 20 of 128

1.
Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury
Ke Lai, Iva Pritišanac, Zhen-Qi Liu, Han-Wei Liu, Li-Na Gong, Ming-Xian Li, Jian-Fei Lu, Xin Qi, Tian-Le Xu, Julie Forman-Kay, Hai-Bo Shi, Lu-Yang Wang, Shan-Kai Yin
Nature. 2024; 631(8022): 826–834. Published online 2024 Jul 10. doi: 10.1038/s41586-024-07684-7
PMCID:
PMC11269185
AbstractArticlePDF–17M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Inhibition of ASIC1a Improves Behavioral Recovery after Stroke
Ariel Armstrong, Tao Yang, Tiandong Leng, Zhi-Gang Xiong
eNeuro. 2024 Feb; 11(2): ENEURO.0341-23.2023. Prepublished online 2024 Jan 17. Published online 2024 Feb 9. doi: 10.1523/ENEURO.0341-23.2023
PMCID:
PMC10866329
AbstractArticlePDF–1.0M
4.
ASIC1a affects hypothalamic signaling and regulates the daily rhythm of body temperature in mice
Zhong Peng, Panos G. Ziros, Tomaz Martini, Xiao-Hui Liao, Ron Stoop, Samuel Refetoff, Urs Albrecht, Gerasimos P. Sykiotis, Stephan Kellenberger
Commun Biol. 2023; 6: 857. Published online 2023 Aug 17. doi: 10.1038/s42003-023-05221-2
PMCID:
PMC10435469
AbstractArticlePDF–1.5M
5.
Effects of acid-sensing ion channel-1A (ASIC1A) on cocaine-induced synaptic adaptations
Subhash C. Gupta, Rebecca J. Taugher-Hebl, Jason B. Hardie, Rong Fan, Ryan T. LaLumiere, John A. Wemmie
Front Physiol. 2023; 14: 1191275. Published online 2023 Jun 14. doi: 10.3389/fphys.2023.1191275
PMCID:
PMC10300415
AbstractArticlePDF–2.1M
6.
Acid-sensing ion channel 1a exacerbates renal ischemia–reperfusion injury through the NF-κB/NLRP3 inflammasome pathway
Yan Yang, Shi Jin, Jian Zhang, Weize Chen, Yufei Lu, Jun Chen, Zhixin Yan, Bo Shen, Yichun Ning, Yiqin Shi, Jing Chen, Jialin Wang, Sujuan Xu, Ping Jia, Jie Teng, Yi Fang, Nana Song, Xiaoqiang Ding
J Mol Med (Berl) 2023; 101(7): 877–890. Published online 2023 May 29. doi: 10.1007/s00109-023-02330-7
PMCID:
PMC10300185
AbstractArticlePDF–10M
7.
Acid-sensing ion channel 1a activates IKCa/SKCa channels and contributes to endothelium-dependent dilation
Selina M. Garcia, Jay S. Naik, Thomas C. Resta, Nikki L. Jernigan
J Gen Physiol. 2023 Feb 6; 155(2): e202213173. Published online 2022 Dec 9. doi: 10.1085/jgp.202213173
PMCID:
PMC9984545
AbstractArticlePDF–4.3M
8.
Carbonic anhydrase 4 disruption decreases synaptic and behavioral adaptations induced by cocaine withdrawal
Subhash C. Gupta, Ali Ghobbeh, Rebecca J. Taugher-Hebl, Rong Fan, Jason B. Hardie, Ryan T. LaLumiere, John A. Wemmie
Sci Adv. 2022 Nov; 8(46): eabq5058. Published online 2022 Nov 16. doi: 10.1126/sciadv.abq5058
PMCID:
PMC9668291
AbstractArticlePDF–1.8M
9.
Smooth muscle Acid-sensing ion channel 1a as a therapeutic target to reverse hypoxic pulmonary hypertension
Selina M. Garcia, Tracy R. Yellowhair, Neil D. Detweiler, Rosstin Ahmadian, Lindsay M. Herbert, Laura V. Gonzalez Bosc, Thomas C. Resta, Nikki L. Jernigan
Front Mol Biosci. 2022; 9: 989809. Published online 2022 Oct 5. doi: 10.3389/fmolb.2022.989809
PMCID:
PMC9581175
AbstractArticlePDF–2.8M
10.
Pharmacological Validation of ASIC1a as a Druggable Target for Neuroprotection in Cerebral Ischemia Using an Intravenously Available Small Molecule Inhibitor
Xin Qi, Jian-Fei Lu, Zi-Yue Huang, Yi-Jun Liu, Lu-Bing Cai, Xin-Lan Wen, Xing-Lei Song, Jian Xiong, Pei-Yi Sun, Hao Zhang, Ting-Ting Zhang, Xuan Zhao, Qin Jiang, Ying Li, Oleg Krishtal, Leng-Chen Hou, Michael X. Zhu, Tian-Le Xu
Front Pharmacol. 2022; 13: 849498. Published online 2022 Mar 24. doi: 10.3389/fphar.2022.849498
PMCID:
PMC8988055
AbstractArticlePDF–1.7M
11.
ASIC1a senses lactate uptake to regulate metabolism in neurons
Ivana Savic Azoulay, Xin Qi, Maya Rozenfeld, Fan Liu, Qin Hu, Tsipi Ben Kasus Nissim, Alexandra Stavsky, Michael X. Zhu, Tian-Le Xu, Israel Sekler
Redox Biol. 2022 May; 51: 102253. Published online 2022 Jan 29. doi: 10.1016/j.redox.2022.102253
PMCID:
PMC8894274
AbstractArticlePDF–5.6M
12.
Acid-sensing ion channel 1a regulates the specificity of reconsolidation of conditioned threat responses
Erin E. Koffman, Charles M. Kruse, Kritika Singh, Farzaneh Sadat Naghavi, Melissa A. Curtis, Jennifer Egbo, Mark Houdi, Boren Lin, Hui Lu, Jacek Debiec, Jianyang Du
JCI Insight. 2022 Feb 22; 7(4): e155341. Published online 2022 Feb 22. doi: 10.1172/jci.insight.155341
PMCID:
PMC8876458
AbstractArticlePDF–5.8M
13.
Acid-sensing ion channel 1 contributes to pulmonary arterial smooth muscle cell depolarization following hypoxic pulmonary hypertension
Nikki L. Jernigan, Jay S. Naik, Thomas C. Resta
J Physiol. Author manuscript; available in PMC 2022 Nov 1.
Published in final edited form as: J Physiol. 2021 Nov; 599(21): 4749–4762. Published online 2021 Sep 25. doi: 10.1113/JP282231
PMCID:
PMC8560573
AbstractArticlePDF–2.2M
14.
Changes in H+, K+, and Ca2+ Concentrations, as Observed in Seizures, Induce Action Potential Signaling in Cortical Neurons by a Mechanism That Depends Partially on Acid-Sensing Ion Channels
Omar Alijevic, Zhong Peng, Stephan Kellenberger
Front Cell Neurosci. 2021; 15: 732869. Published online 2021 Oct 15. doi: 10.3389/fncel.2021.732869
PMCID:
PMC8553998
AbstractArticlePDF–16M
15.
C-Jun N-Terminal Kinase Post-Translational Regulation of Pain-Related Acid-Sensing Ion Channels 1b and 3
Clément Verkest, Sylvie Diochot, Eric Lingueglia, Anne Baron
J Neurosci. 2021 Oct 20; 41(42): 8673–8685. doi: 10.1523/JNEUROSCI.0570-21.2021
PMCID:
PMC8528506
AbstractArticlePDF–2.5M
16.
ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brain
Jormay Lim, Hsiao-Hsin Tai, Wei-Hao Liao, Ya-Cherng Chu, Chen-Ming Hao, Yueh-Chun Huang, Cheng-Han Lee, Shao-Shien Lin, Sherry Hsu, Ya-Chih Chien, Dar-Ming Lai, Wen-Shiang Chen, Chih-Cheng Chen, Jaw-Lin Wang
eLife. 2021; 10: e61660. Published online 2021 Sep 27. doi: 10.7554/eLife.61660
PMCID:
PMC8510583
AbstractArticlePDF–19M
17.
Upregulation of acid sensing ion channel 1a (ASIC1a) by hydrogen peroxide through the JNK pathway
Bao-ming Wu, Jaree Bargaineer, Ling Zhang, Tao Yang, Zhi-gang Xiong, Tian-dong Leng
Acta Pharmacol Sin. 2021 Aug; 42(8): 1248–1255. Published online 2020 Nov 12. doi: 10.1038/s41401-020-00559-3
PMCID:
PMC8285496
AbstractArticlePDF–2.1M
18.
Citric Acid in Drug Formulations Causes Pain by Potentiating Acid-Sensing Ion Channel 1
Ya Lan Yang, Ted Weita Lai
J Neurosci. 2021 May 26; 41(21): 4596–4606. doi: 10.1523/JNEUROSCI.2087-20.2021
PMCID:
PMC8260239
AbstractArticlePDF–1.4M
19.
Activation of acid‐sensing ion channels by carbon dioxide regulates amygdala synaptic protein degradation in memory reconsolidation
Boren Lin, Khaled Alganem, Sinead M. O’Donovan, Zhen Jin, FarzanehSadat Naghavi, Olivia A. Miller, Tyler C. Ortyl, Ye Chun Ruan, Robert E. McCullumsmith, Jianyang Du
Mol Brain. 2021; 14: 78. Published online 2021 May 7. doi: 10.1186/s13041-021-00786-7
PMCID:
PMC8106190
AbstractArticlePDF–2.0M
20.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M

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