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Select item 112897371.

The Interferon-Stimulated Gene RIPK1 Regulates Cancer Cell Intrinsic and Extrinsic Resistance to Immune Checkpoint Blockade

Lisa Cucolo, Qingzhou Chen, Jingya Qiu, Yongjun Yu, Max Klapholz, Krista Budinich, Zhaojun Zhang, Yue Shao, Igor E. Brodsky, Martha S. Jordan, D. Gary Gilliland, Nancy R. Zhang, Junwei Shi, Andy J. Minn

Immunity. Author manuscript; available in PMC 2024 Jul 31.

Published in final edited form as: Immunity. 2022 Apr 12; 55(4): 671–685.e10. doi: 10.1016/j.immuni.2022.03.007

PMCID:: PMC11289737

Abstract Article PDF–3.5M

Select item 111589592.

Modulation of RIP1 ubiquitylation and distribution by MeBS to sensitize cancer cells to tumor necrosis factor α‐induced apoptosis

Seungseob Kim, Nobumichi Ohoka, Keiichiro Okuhira, Kimie Sai, Tomoko Nishimaki‐Mogami, Mikihiko Naito

Cancer Sci. 2010 Nov; 101(11): 2425–2429. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01697.x

PMCID:: PMC11158959

Abstract Article PDF–365K

Select item 110727663.

Cell adhesion tunes inflammatory TPL2 kinase signal transduction

Maria Vougioukalaki, Konstantina Georgila, Emmanouil I. Athanasiadis, Aristides G. Eliopoulos

Cell Mol Life Sci. 2022 Mar; 79(3): 156. Published online 2022 Feb 26. doi: 10.1007/s00018-022-04130-7

PMCID:: PMC11072766

Abstract Article PDF–2.1M

Select item 110241794.

TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers

Helene Damhofer, Tülin Tatar, Benjamin Southgate, Scott Scarneo, Karl Agger, Daria Shlyueva, Lene Uhrbom, Gillian M. Morrison, Philip F. Hughes, Timothy Haystead, Steven M. Pollard, Kristian Helin

Cell Death Dis. 2024 Apr; 15(4): 273. Published online 2024 Apr 17. doi: 10.1038/s41419-024-06654-1

PMCID:: PMC11024179

Abstract Article PDF–6.6M

Select item 107161925.

Elevated peripheral levels of receptor-interacting protein kinase 1 (RIPK1) and IL-8 as biomarkers of human amyotrophic lateral sclerosis

Jun Wei, Min Li, Zhi Ye, Xinqian Hu, Xiaoyan He, Jia Wang, Gaofeng Chen, Chengyu Zou, Daichao Xu, Hongbing Zhang, Junying Yuan, Yunhong Zha

Signal Transduct Target Ther. 2023; 8: 451. Published online 2023 Dec 13. doi: 10.1038/s41392-023-01713-z

PMCID:: PMC10716192

Abstract Article PDF–2.7M

Select item 105687856.

Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation

Yuanbang Lin, Mingwei Sheng, Hua Qin, Peng Zhang, Chunli Wang, Wei Fu, Xiangjun Meng, Duowei Wang, Yachao Hou

Cell Commun Signal. 2023; 21: 282. Published online 2023 Oct 12. doi: 10.1186/s12964-023-01287-x

PMCID:: PMC10568785

Abstract Article PDF–12M

Select item 102890047.

O-GlcNAcylation of RIPK1 rescues red blood cells from necroptosis

Junghwa Seo, Yeolhoe Kim, Suena Ji, Han Byeol Kim, Hyeryeon Jung, Eugene C. Yi, Yong-ho Lee, Injae Shin, Won Ho Yang, Jin Won Cho

Front Immunol. 2023; 14: 1160490. Published online 2023 Jun 9. doi: 10.3389/fimmu.2023.1160490

PMCID:: PMC10289004

Abstract Article PDF–17M

Select item 102443838.

IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death

Choong-Sil Lee, Gyuho Hwang, Young Woo Nam, Chi Hyun Hwang, Jaewhan Song

Cell Death Differ. 2023 Jun; 30(6): 1575–1584. Published online 2023 Apr 21. doi: 10.1038/s41418-023-01161-w

PMCID:: PMC10244383

Abstract Article PDF–2.8M

Select item 102374229.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1020334310.

RIPK1-dependent necroptosis promotes vasculogenic mimicry formation via eIF4E in triple-negative breast cancer

Fan Li, Huizhi Sun, Yihui Yu, Na Che, Jiyuan Han, Runfen Cheng, Nan Zhao, Yuhong Guo, Chongbiao Huang, Danfang Zhang

Cell Death Dis. 2023 May; 14(5): 335. Published online 2023 May 22. doi: 10.1038/s41419-023-05841-w

Correction in:: Cell Death Dis. 2023 Sep; 14(9): 607.

PMCID:: PMC10203343

Abstract Article PDF–8.5M

Select item 1011942711.

Curcumin alleviates experimental colitis in mice by suppressing necroptosis of intestinal epithelial cells

Yuting Zhong, Ye Tu, Qingshan Ma, Linlin Chen, Wenzhao Zhang, Xin Lu, Shuo Yang, Zhibin Wang, Lichao Zhang

Front Pharmacol. 2023; 14: 1170637. Published online 2023 Apr 7. doi: 10.3389/fphar.2023.1170637

Correction in:: Front Pharmacol. 2023; 14: 1240661.

PMCID:: PMC10119427

Abstract Article PDF–3.7M

Select item 1007290612.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 985197313.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

Select item 981617314.

TRAF6 regulates the abundance of RIPK1 and inhibits the RIPK1/RIPK3/MLKL necroptosis signaling pathway and affects the progression of colorectal cancer

Penghang Lin, Chunlin Lin, Ruofan He, Hui Chen, Zuhong Teng, Hengxin Yao, Songyi Liu, Robert M. Hoffman, Jianxin Ye, Guangwei Zhu

Cell Death Dis. 2023 Jan; 14(1): 6. Published online 2023 Jan 5. doi: 10.1038/s41419-022-05524-y

PMCID:: PMC9816173

Abstract Article PDF–6.3M

Select item 972467115.

Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1

Ruoshi Peng, Chris Kedong Wang, Xuan Wang‐Kan, Manja Idorn, Majken Kjær, Felix Y Zhou, Berthe Katrine Fiil, Frederik Timmermann, Susana L Orozco, Julia McCarthy, Carol S Leung, Xin Lu, Katrin Bagola, Jan Rehwinkel, Andrew Oberst, Jonathan Maelfait, Søren R Paludan, Mads Gyrd‐Hansen

EMBO Rep. 2022 Dec; 23(12): e55839. Published online 2022 Oct 21. doi: 10.15252/embr.202255839

PMCID:: PMC9724671

Abstract Article PDF–1.8M

Select item 971646916.

RIPK1 mutations causing infantile-onset IBD with inflammatory and fistulizing features

Mutaz Sultan, Mohammad Adawi, Nitzan Kol, Blake McCourt, Ihda Adawi, Liran Baram, Noa Tal, Lael Werner, Atar Lev, Scott B. Snapper, Ortal Barel, Liza Konnikova, Raz Somech, Dror S. Shouval

Front Immunol. 2022; 13: 1041315. Published online 2022 Nov 18. doi: 10.3389/fimmu.2022.1041315

PMCID:: PMC9716469

Abstract Article PDF–2.5M

Select item 967470817.

Characterization of Novel Pathogenic Variants Leading to Caspase-8 Cleavage-Resistant RIPK1-Induced Autoinflammatory Syndrome

Alfonso José Tapiz i Reula, Alexis-Virgil Cochino, Andreia L. Martins, Diego Angosto-Bazarra, Iñaki Ortiz de Landazuri, Anna Mensa-Vilaró, Marta Cabral, Alberto Baroja-Mazo, María C. Baños, Zulema Lobato-Salinas, Virginia Fabregat, Susana Plaza, Jordi Yagüe, Ferran Casals, Baldomero Oliva, Antonio E. Figueiredo, Pablo Pelegrín, Juan I. Aróstegui

J Clin Immunol. 2022; 42(7): 1421–1432. Published online 2022 Jun 18. doi: 10.1007/s10875-022-01298-2

Correction in:: J Clin Immunol. 2022; 42(7): 1433.

PMCID:: PMC9674708

Abstract Article PDF–1.3M

Select item 961591818.

Dengue virus downregulates TNFR1- and TLR3-stimulated NF-κB activation by targeting RIPK1

Darshika J. Udawatte, Diane M. Lang, Jeffrey R. Currier, Carey L. Medin, Alan L. Rothman

Front Cell Infect Microbiol. 2022; 12: 926036. Published online 2022 Oct 14. doi: 10.3389/fcimb.2022.926036

PMCID:: PMC9615918

Abstract Article PDF–8.7M

Select item 948193319.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 946496520.

RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity

Christopher J. Contreras, Noyonika Mukherjee, Renato C.S. Branco, Li Lin, Meghan F. Hogan, Erica P. Cai, Andrew A. Oberst, Steven E. Kahn, Andrew T. Templin

Mol Metab. 2022 Nov; 65: 101582. Published online 2022 Aug 24. doi: 10.1016/j.molmet.2022.101582

PMCID:: PMC9464965

Abstract Article PDF–4.0M

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