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Items: 1 to 20 of 65

1.
Proximity labeling reveals dynamic changes in the SQSTM1 protein network
Alejandro N. Rondón-Ortiz, Lushuang Zhang, Peter E.A. Ash, Avik Basu, Sambhavi Puri, Sophie J.F. van der Spek, Zihan Wang, Luke Dorrian, Andrew Emili, Benjamin Wolozin
J Biol Chem. 2024 Sep; 300(9): 107621. Published online 2024 Aug 3. doi: 10.1016/j.jbc.2024.107621
PMCID:
PMC11401034
AbstractArticlePDF–5.4M
2.
A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex
Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll
EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9
PMCID:
PMC11315929
AbstractArticlePDF–3.4M
3.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
4.
Diverse p120RasGAP interactions with doubly phosphorylated partners EphB4, p190RhoGAP, and Dok1
Kimberly J. Vish, Amy L. Stiegler, Titus J. Boggon
J Biol Chem. 2023 Sep; 299(9): 105098. Published online 2023 Jul 27. doi: 10.1016/j.jbc.2023.105098
PMCID:
PMC10470053
AbstractArticlePDF–3.2M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
6.
ARHGAP35 is a novel factor disrupted in human developmental eye phenotypes
Linda M. Reis, Nicolas Chassaing, Tanya Bardakjian, Samuel Thompson, Adele Schneider, Elena V. Semina
Eur J Hum Genet. 2023 Mar; 31(3): 363–367. Published online 2022 Dec 1. doi: 10.1038/s41431-022-01246-z
PMCID:
PMC9995503
AbstractArticlePDF–878K
7.
Interactomes of Glycogen Synthase Kinase-3 Isoforms
Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett
J Proteome Res. 2023 Mar 3; 22(3): 977–989. Published online 2023 Feb 13. doi: 10.1021/acs.jproteome.2c00825
PMCID:
PMC9990120
AbstractArticlePDF–3.7M
8.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
9.
Identification of an inhibitory domain in GTPase-activating protein p190RhoGAP responsible for masking its functional GAP domain
Capucine Héraud, Mathilde Pinault, Véronique Neaud, Frédéric Saltel, Valérie Lagrée, Violaine Moreau
J Biol Chem. 2023 Jan; 299(1): 102792. Published online 2022 Dec 11. doi: 10.1016/j.jbc.2022.102792
PMCID:
PMC9840978
AbstractArticlePDF–5.6M
10.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
11.
The p190 RhoGAPs, ARHGAP35 and ARHGAP5, are Implicated in GnRH Neuronal Development: Evidence from Patients with Idiopathic Hypogonadotropic Hypogonadism, Zebrafish and in vitro GAP Activity Assay
Margaret F. Lippincott, Wanxue Xu, Abigail A. Smith, Xinyu Miao, Agathe Lafont, Omar Shennib, Gordon J. Farley, Riwa Sabbagh, Angela Delaney, Maria Stamou, Lacey Plummer, Kathryn Salnikov, Neoklis A. Georgopoulos, Veronica Mericq, Richard Quinton, Frederic Tran Mau-Them, Sophie Nambot, Asma Hamad, Helen Brittain, Rebecca S. Tooze, Eduardo Calpena, Andrew O.M. Wilkie, Marjolaine Willems, William F. Crowley, Ravikumar Balasubramanian, Nathalie Lamarche-Vane, Erica E. Davis, Stephanie B. Seminara
Genet Med. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Genet Med. 2022 Dec; 24(12): 2501–2515. Published online 2022 Sep 30. doi: 10.1016/j.gim.2022.08.025
PMCID:
PMC9730938
AbstractArticlePDF–1.2M
12.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
13.
Rho GTPase-activating protein 35 suppresses gastric cancer metastasis by regulating cytoskeleton reorganization and epithelial-to-mesenchymal transition
Yi Sun, Rui Du, Yulong Shang, Changhao Liu, Linhua Zheng, Ruiqing Sun, Yuanyong Wang, Guofang Lu
Bioengineered. 2022; 13(6): 14605–14615. Published online 2022 Jun 26. doi: 10.1080/21655979.2022.2092677
PMCID:
PMC9342288
AbstractArticlePDF–7.3M
14.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
15.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
16.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
17.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
18.
N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective
Veronique Jonckheere, Petra Van Damme
Int J Mol Sci. 2021 Apr; 22(7): 3690. Published online 2021 Apr 1. doi: 10.3390/ijms22073690
PMCID:
PMC8037211
AbstractArticlePDF–6.5M
19.
Polycystin-1 regulates ARHGAP35-dependent centrosomal RhoA activation and ROCK signaling
Andrew J. Streets, Philipp P. Prosseda, Albert C.M. Ong
JCI Insight. 2020 Aug 20; 5(16): e135385. Published online 2020 Aug 20. doi: 10.1172/jci.insight.135385
PMCID:
PMC7455122
AbstractArticlePDF–12M
20.
p190A RhoGAP induces CDH1 expression and cooperates with E-cadherin to activate LATS kinases and suppress tumor cell growth
Hanyue Ouyang, Phi Luong, Morten Frödin, Steen H. Hansen
Oncogene. 2020; 39(33): 5570–5587. Published online 2020 Jul 8. doi: 10.1038/s41388-020-1385-2
PMCID:
PMC7426264
AbstractArticlePDF–5.8M

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