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Select item 101249071.

The YAP–TEAD4 complex promotes tumor lymphangiogenesis by transcriptionally upregulating CCBE1 in colorectal cancer

Jinglue Song, Xuening Dang, Xia Shen, Yun Liu, Jiani Gu, Xiang Peng, Zhenyu Huang, Wanjin Hong, Long Cui, Chen-Ying Liu

J Biol Chem. 2023 Apr; 299(4): 103012. Published online 2023 Feb 11. doi: 10.1016/j.jbc.2023.103012

PMCID:: PMC10124907

Abstract Article PDF–5.4M

Select item 87388652.

Hsa_circ_0076931 suppresses malignant biological properties, down-regulates miR-6760-3p through direct binding, and up-regulates CCBE1 in glioma

Yanbin Ke, Shixing Su, Chuanzhi Duan, Yezhong Wang, Guobin Cao, Zelu Fang, Yonghua Tuo, Wei Li, Zhaotao Wang, Shizhen Zhang

Biosci Rep. 2022 Jan 28; 42(1): BSR20211895. Published online 2022 Jan 6. doi: 10.1042/BSR20211895

PMCID:: PMC8738865

Abstract Article PDF–3.5M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81021004.

miR-942-5p Inhibits Proliferation, Metastasis, and Epithelial-Mesenchymal Transition in Colorectal Cancer by Targeting CCBE1

Lin Zhou, Qing Chen, Jie Wu, Jian Yang, Huancai Yin, Jingjing Tian, Lian Gong, DanDan Kong, Min Tao

Biomed Res Int. 2021; 2021: 9951405. Published online 2021 Apr 28. doi: 10.1155/2021/9951405

PMCID:: PMC8102100

Abstract Article PDF–2.1M

Select item 74794605.

A Novel RNA-Seq-Based Model for Preoperative Prediction of Lymph Node Metastasis in Oral Squamous Cell Carcinoma

Bo Qiao, Min Zhao, Jing Wu, Huan Wu, Yiming Zhao, Fanhao Meng, Yu Tian, Situo Wang, Jinlong Shi, Haizhong Zhang

Biomed Res Int. 2020; 2020: 4252580. Published online 2020 Aug 31. doi: 10.1155/2020/4252580

PMCID:: PMC7479460

Abstract Article PDF–1.3M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 61666827.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 57834508.

Clinical significance of CCBE1 expression in lung cancer

Peng Li, Zhuangzhuang Cong, Yong Qiang, Lei Xiong, Li Tang, Yu Zhang, Haiwei Wu, Jun Yi, Hua Jing, Demin Li, Yi Shen

Mol Med Rep. 2018 Feb; 17(2): 2107–2112. Published online 2017 Nov 29. doi: 10.3892/mmr.2017.8187

PMCID:: PMC5783450

Abstract Article PDF–1.1M

Select item 55018419.

Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1

Sawan Kumar Jha, Khushbu Rauniyar, Terhi Karpanen, Veli-Matti Leppänen, Pascal Brouillard, Miikka Vikkula, Kari Alitalo, Michael Jeltsch

Sci Rep. 2017; 7: 4916. Published online 2017 Jul 7. doi: 10.1038/s41598-017-04982-1

PMCID:: PMC5501841

Abstract Article PDF–9.5M

Select item 548272710.

Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis

Aruz Mesci, Xiaoyong Huang, Samira Taeb, Sahar Jahangiri, Yohan Kim, Emmanouil Fokas, Jeff Bruce, Hon S Leong, Stanley K Liu

Br J Cancer. 2017 May 9; 116(10): 1350–1357. Published online 2017 Apr 18. doi: 10.1038/bjc.2017.105

PMCID:: PMC5482727

Abstract Article PDF–1.1M

Select item 526093911.

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman

Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387

PMCID:: PMC5260939

Abstract Article PDF–1.1M

Select item 498426812.

A Multiplex Kindred with Hennekam Syndrome due to Homozygosity for a CCBE1 Mutation that does not Prevent Protein Expression

Carolyn C. Jackson, Lucy Best, Lazaro Lorenzo, Jean-Laurent Casanova, Jochen Wacker, Simone Bertz, Abbas Agaimy, Thomas Harrer

J Clin Immunol. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: J Clin Immunol. 2016 Jan; 36(1): 19–27. Published online 2015 Dec 19. doi: 10.1007/s10875-015-0225-6

PMCID:: PMC4984268

Abstract Article PDF–2.5M

Select item 497899713.

CCBE1 promotes GIST development through enhancing angiogenesis and mediating resistance to imatinib

Guang-Ang Tian, Chun-Chao Zhu, Xiao-Xin Zhang, Lei Zhu, Xiao-Mei Yang, Shu-Heng Jiang, Rong-Kun Li, Lin Tu, Yang Wang, Chun Zhuang, Ping He, Qing Li, Xiao-Yan Cao, Hui Cao, Zhi-Gang Zhang

Sci Rep. 2016; 6: 31071. Published online 2016 Aug 10. doi: 10.1038/srep31071

PMCID:: PMC4978997

Abstract Article PDF–3.0M

Select item 426674114.

Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment

Erik Fransen, Sarah Bonneux, Jason J Corneveaux, Isabelle Schrauwen, Federica Di Berardino, Cory H White, Jeffrey D Ohmen, Paul Van de Heyning, Umberto Ambrosetti, Matthew J Huentelman, Guy Van Camp, Rick A Friedman

Eur J Hum Genet. 2015 Jan; 23(1): 110–115. Published online 2014 Jun 18. doi: 10.1038/ejhg.2014.56

PMCID:: PMC4266741

Abstract Article PDF–823K

Select item 426658815.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 378439616.

CCBE1 Mutation in Two Siblings, One Manifesting Lymphedema-Cholestasis Syndrome, and the Other, Fetal Hydrops

Sohela Shah, Laura K. Conlin, Luis Gomez, Øystein Aagenaes, Kristin Eiklid, A. S. Knisely, Michael T. Mennuti, Randolph P. Matthews, Nancy B. Spinner, Laura N. Bull

PLoS One. 2013; 8(9): e75770. Published online 2013 Sep 26. doi: 10.1371/journal.pone.0075770

PMCID:: PMC3784396

Abstract Article PDF–728K

Select item 326170817.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67