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Select item 107922471.

Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart

Abhishek Mishra, Mahtab Tavasoli, Stanislav Sokolenko, Christopher R. McMaster, Kishore B.S. Pasumarthi

iScience. 2024 Jan 19; 27(1): 108748. Published online 2023 Dec 14. doi: 10.1016/j.isci.2023.108748

PMCID:: PMC10792247

Abstract Article PDF–9.2M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 96038603.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 85529714.

Conditional Knockout of Pdha1 in Mouse Hippocampus Impairs Cognitive Function: The Possible Involvement of Lactate

Wanxin Chen, Xiaoxia Sun, Libin Zhan, Wen Zhou, Tingting Bi

Front Neurosci. 2021; 15: 767560. Published online 2021 Oct 14. doi: 10.3389/fnins.2021.767560

PMCID:: PMC8552971

Abstract Article PDF–5.5M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 77850546.

Reprogramming of aerobic glycolysis in non‐transformed mouse liver with pyruvate dehydrogenase complex deficiency

Mulchand S. Patel, Saleh Mahmood, Jiwon Jung, Todd C. Rideout

Physiol Rep. 2021 Jan; 9(1): e14684. Published online 2021 Jan 5. doi: 10.14814/phy2.14684

Correction in:: Physiol Rep. 2021 Mar; 9(5): e14793.

PMCID:: PMC7785054

Abstract Article PDF–1.2M

Select item 75347357.

Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis

Zhen Cai, Chien-Feng Li, Fei Han, Chunfang Liu, Anmei Zhang, Che-Chia Hsu, Danni Peng, Xian Zhang, Guoxiang Jin, Abdol-Hossein Rezaeian, Guihua Wang, Weina Zhang, Bo-Syong Pan, Chi-Yun Wang, Yu-Hui Wang, Shih-Ying Wu, Shun-Chin Yang, Fang-Chi Hsu, Ralph B. D’Agostino, Jr., Christina M. Furdui, Gregory L. Kucera, John S. Parks, Floyd H. Chilton, Chih-Yang Huang, Fuu-Jen Tsai, Boris Pasche, Kounosuke Watabe, Hui-Kuan Lin

Mol Cell. 2020 Oct 15; 80(2): 263–278.e7. Published online 2020 Oct 5. doi: 10.1016/j.molcel.2020.09.018

PMCID:: PMC7534735

Abstract Article PDF–7.1M

Select item 70577768.

Conditional knockout of pyruvate dehydrogenase in mouse pancreatic β-cells causes morphological and functional changes

Xiao Wang, Shuchang Lai, Yanshi Ye, Yuanyuan Hu, Daoyan Pan, Xiaochun Bai, Jie Shen

Mol Med Rep. 2020 Apr; 21(4): 1717–1726. Published online 2020 Feb 20. doi: 10.3892/mmr.2020.10993

PMCID:: PMC7057776

Abstract Article PDF–1.3M

Select item 66923359.

Sirtuin 3-mediated pyruvate dehydrogenase activity determines brown adipocytes phenotype under high-salt conditions

Tong Wei, Gaojian Huang, Penghao Liu, Jing Gao, Chenglin Huang, Mengwei Sun, Weili Shen

Cell Death Dis. 2019 Aug; 10(8): 614. Published online 2019 Aug 14. doi: 10.1038/s41419-019-1834-4

PMCID:: PMC6692335

Abstract Article PDF–3.3M

Select item 631390010.

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II

Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053

Correction in:: Proteomes. 2019 Mar; 7(1): 7.

PMCID:: PMC6313900

Abstract Article PDF–2.5M

Select item 629804011.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 629317012.

Defining the contribution of skeletal muscle pyruvate dehydrogenase α1 to exercise performance and insulin action

Kristoffer Svensson, Jessica R. Dent, Shahriar Tahvilian, Vitor F. Martins, Abha Sathe, Julien Ochala, Mulchand S. Patel, Simon Schenk

Am J Physiol Endocrinol Metab. 2018 Nov 1; 315(5): E1034–E1045. Published online 2018 Aug 28. doi: 10.1152/ajpendo.00241.2018

PMCID:: PMC6293170

Abstract Article

Select item 584564613.

Cardiac-Specific Deletion of Pyruvate Dehydrogenase Impairs Glucose Oxidation Rates and Induces Diastolic Dysfunction

Keshav Gopal, Malak Almutairi, Rami Al Batran, Farah Eaton, Manoj Gandhi, John Reyes Ussher

Front Cardiovasc Med. 2018; 5: 17. Published online 2018 Mar 6. doi: 10.3389/fcvm.2018.00017

PMCID:: PMC5845646

Abstract Article PDF–1.6M

Select item 581091214.

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer

Jingjing Chen, Ilaria Guccini, Diletta Di Mitri, Daniela Brina, Ajinkya Revandkar, Manuela Sarti, Emiliano Pasquini, Abdullah Alajati, Sandra Pinton, Marco Losa, Gianluca Civenni, Carlo V. Catapano, Jacopo Sgrignani, Andrea Cavalli, Rocco D'Antuono, John M. Asara, Andrea Morandi, Paola Chiarugi, Sara Crotti, Marco Agostini, Monica Montopoli, Ionica Masgras, Andrea Rasola, Ramon Garcia-Escudero, Nicolas Delaleu, Andrea Rinaldi, Francesco Bertoni, Johann de Bono, Arkaitz Carracedo, Andrea Alimonti

Nat Genet. Author manuscript; available in PMC 2018 Jul 15.

Published in final edited form as: Nat Genet. 2018 Feb; 50(2): 219–228. Published online 2018 Jan 15. doi: 10.1038/s41588-017-0026-3

PMCID:: PMC5810912

Abstract Article PDF–1.9M

Select item 579902315.

Chemical cross-linking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue

Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Andrew Keller, Rong Tian, James E. Bruce

Cell Syst. Author manuscript; available in PMC 2019 Jan 24.

Published in final edited form as: Cell Syst. 2018 Jan 24; 6(1): 136–141.e5. Published online 2017 Nov 29. doi: 10.1016/j.cels.2017.10.017

PMCID:: PMC5799023

Abstract Article PDF–730K

Select item 579538816.

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes

Fan Liu, Philip Lössl, Beverley M. Rabbitts, Robert S. Balaban, Albert J. R. Heck

Mol Cell Proteomics. 2018 Feb; 17(2): 216–232. Published online 2017 Dec 8. doi: 10.1074/mcp.RA117.000470

PMCID:: PMC5795388

Abstract Article PDF–4.4M

Select item 577347217.

Characterization of the impact of glutaredoxin-2 (GRX2) deficiency on superoxide/hydrogen peroxide release from cardiac and liver mitochondria

Julia Chalker, Danielle Gardiner, Nidhi Kuksal, Ryan J. Mailloux

Redox Biol. 2018 May; 15: 216–227. Published online 2017 Dec 14. doi: 10.1016/j.redox.2017.12.006

PMCID:: PMC5773472

Abstract Article PDF–1.3M

Select item 574645518.

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals Molecular Determinants of Redox Homeostasis and NF-κB Signaling

Ramy H. Malty, Hiroyuki Aoki, Ashwani Kumar, Sadhna Phanse, Shahreen Amin, Qingzhou Zhang, Zoran Minic, Florian Goebels, Gabriel Musso, Zhuoran Wu, Hosam Abou-tok, Michael Meyer, Viktor Deineko, Sandy Kassir, Vishaldeep Sidhu, Matthew Jessulat, Nichollas E. Scott, Xuejian Xiong, James Vlasblom, Bhanu Prasad, Leonard J. Foster, Tiziana Alberio, Barbara Garavaglia, Haiyuan Yu, Gary D. Bader, Ken Nakamura, John Parkinson, Mohan Babu

Cell Syst. Author manuscript; available in PMC 2018 Dec 27.

Published in final edited form as: Cell Syst. 2017 Dec 27; 5(6): 564–577.e12. Published online 2017 Nov 8. doi: 10.1016/j.cels.2017.10.010

PMCID:: PMC5746455

Abstract Article PDF–3.3M

Select item 566814519.

Genetic dissociation of glycolysis and the TCA cycle affects neither normal nor neoplastic proliferation

Laura E. Jackson, Sucheta Kulkarni, Huabo Wang, Jie Lu, James M. Dolezal, Sivakama S. Bharathi, Sarangarajan Ranganathan, Mulchand S. Patel, Rahul Deshpande, Frances Alencastro, Stacy G. Wendell, Eric S. Goetzman, Andrew W. Duncan, Edward V. Prochownik

Cancer Res. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Cancer Res. 2017 Nov 1; 77(21): 5795–5807. Published online 2017 Sep 7. doi: 10.1158/0008-5472.CAN-17-1325

Correction in:: Cancer Res. 2022 Mar 1; 82(5): 944.

PMCID:: PMC5668145

Abstract Article PDF–823K

Select item 556151920.

Acetyl-CoA production from pyruvate is not necessary for preservation of myelin

Gustavo Della-Flora Nunes, Lauren Mueller, Nicholas Silvestri, Mulchand S Patel, Lawrence Wrabetz, M Laura Feltri, Yannick Poitelon

Glia. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Glia. 2017 Oct; 65(10): 1626–1639. Published online 2017 Jun 28. doi: 10.1002/glia.23184

PMCID:: PMC5561519

Abstract Article PDF–1.2M

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