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Items: 1 to 20 of 133

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
β-Catenin transcriptional activity is required for establishment of inner pillar cell identity during cochlear development
Michael Ebeid, Ippei Kishimoto, Pooja Roy, Mohd Ali Abbas Zaidi, Alan G. Cheng, Sung-Ho Huh
PLoS Genet. 2023 Aug; 19(8): e1010925. Published online 2023 Aug 28. doi: 10.1371/journal.pgen.1010925
PMCID:
PMC10491406
AbstractArticlePDF–3.9M
3.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
4.
Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice
Ines Leca, Alexander William Phillips, Lyubov Ushakova, Thomas David Cushion, David Anthony Keays
Sci Rep. 2023; 13: 1215. Published online 2023 Jan 21. doi: 10.1038/s41598-023-27782-2
PMCID:
PMC9867703
AbstractArticlePDF–4.1M
5.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
6.
A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability
Sebastian H.J. Koochaki, Mikołaj Słabicki, Ryan Lumpkin, Charles Zou, Roger Belizaire, Eric S. Fischer, Benjamin L. Ebert
J Biol Chem. 2022 Oct; 298(10): 102484. Published online 2022 Sep 13. doi: 10.1016/j.jbc.2022.102484
PMCID:
PMC9574515
AbstractArticlePDF–1.8M
7.
Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states
Huikai Liu, Liwen He, Qianyu Cheng, Wenping Luo, Tianyu Zhao, Deqin Yang
Int J Mol Med. 2022 Nov; 50(5): 132. Published online 2022 Sep 5. doi: 10.3892/ijmm.2022.5188
PMCID:
PMC9559174
AbstractArticlePDF–2.9M
8.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
9.
TUBA1A tubulinopathy mutants disrupt neuron morphogenesis and override XMAP215/Stu2 regulation of microtubule dynamics
Katelyn J Hoff, Jayne E Aiken, Mark A Gutierrez, Santos J Franco, Jeffrey K Moore
eLife. 2022; 11: e76189. Published online 2022 May 5. doi: 10.7554/eLife.76189
PMCID:
PMC9236607
AbstractArticlePDF–3.4M
10.
UHRF1 establishes crosstalk between somatic and germ cells in male reproduction
Yanqing Wu, Peng Duan, Yujiao Wen, Jin Zhang, Xiaoli Wang, Juan Dong, Qiang Zhao, Shenglei Feng, Chunyu Lv, Yang Guo, Satoshi H. Namekawa, Shuiqiao Yuan
Cell Death Dis. 2022 Apr; 13(4): 377. Published online 2022 Apr 19. doi: 10.1038/s41419-022-04837-2
PMCID:
PMC9018721
AbstractArticlePDF–18M
11.
Gag‐like proteins: Novel mediators of prenatal alcohol exposure in neural development
Marisa R. Pinson, Dae D. Chung, Amanda H. Mahnke, Nihal A. Salem, Daniel Osorio, Vijay Nair, Elizabeth A. Payne, Jonathan J. del Real, James J. Cai, Rajesh C. Miranda
Alcohol Clin Exp Res. 2022 Apr; 46(4): 556–569. Published online 2022 Mar 2. doi: 10.1111/acer.14796
PMCID:
PMC9018584
AbstractArticlePDF–1.8M
12.
DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis
Yanchuan Li, Xiaoping Xie, Zuliang Jie, Lele Zhu, Jin-Young Yang, Chun-Jung Ko, Tianxiao Gao, Antrix Jain, Sung Yun Jung, Natalia Baran, Marina Y. Konopleva, Xuhong Cheng, Shao-Cong Sun
Blood. 2021 Dec 9; 138(23): 2360–2371. doi: 10.1182/blood.2021011247
PMCID:
PMC8832461
AbstractArticle
13.
Bridging the Gap: The Importance of TUBA1A α-Tubulin in Forming Midline Commissures
Georgia Buscaglia, Kyle R. Northington, Jayne Aiken, Katelyn J. Hoff, Emily A. Bates
Front Cell Dev Biol. 2021; 9: 789438. Published online 2022 Jan 19. doi: 10.3389/fcell.2021.789438
PMCID:
PMC8807549
AbstractArticlePDF–4.3M
14.
ACAA2 is a Ligand-dependent Coactivator for Thyroid Hormone Receptor β1
Wesley Wang, Dolena Ledee
Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 22.
Published in final edited form as: Biochem Biophys Res Commun. 2021 Oct 22; 576: 15–21. Published online 2021 Aug 28. doi: 10.1016/j.bbrc.2021.08.073
PMCID:
PMC8446338
AbstractArticlePDF–830K
15.
Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity
Alexander Mattebo, Taha Sen, Maria Jassinskaja, Kristýna Pimková, Isabel Prieto González-Albo, Abdul Ghani Alattar, Ramprasad Ramakrishnan, Stefan Lang, Marcus Järås, Jenny Hansson, Shamit Soneji, Sofie Singbrant, Emile van den Akker, Johan Flygare
Sci Rep. 2021; 11: 15898. Published online 2021 Aug 5. doi: 10.1038/s41598-021-95291-1
PMCID:
PMC8342551
AbstractArticlePDF–2.5M
16.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
17.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
18.
A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse
Ines Leca, Alexander William Phillips, Iris Hofer, Lukas Landler, Lyubov Ushakova, Thomas David Cushion, Gerhard Dürnberger, Karel Stejskal, Karl Mechtler, David Anthony Keays
PLoS Genet. 2020 Nov; 16(11): e1009104. Published online 2020 Nov 2. doi: 10.1371/journal.pgen.1009104
PMCID:
PMC7660477
AbstractArticlePDF–5.2M
19.
HDAC6‐mediated α‐tubulin deacetylation suppresses autophagy and enhances motility of podocytes in diabetic nephropathy
Tiantian Liang, Chunfang Qi, Yuxiong Lai, Jianteng Xie, Huizhen Wang, Li Zhang, Ting Lin, Menglei Jv, Jing Li, Yanhui Wang, Yifan Zhang, Zujiao Chen, Xueqian Qiu, Ruizhao Li, Zhilian Li, Zhiming Ye, Shuangxin Liu, Xinling Liang, Wei Shi, Wenjian Wang
J Cell Mol Med. 2020 Oct; 24(19): 11558–11572. Published online 2020 Sep 4. doi: 10.1111/jcmm.15772
PMCID:
PMC7576268
AbstractArticlePDF–2.6M
20.
Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology
Liam Argent, Friederike Winter, Imogen Prickett, Maria Carrasquero-Ordaz, Abby L. Olsen, Holger Kramer, Eric Lancaster, Esther B. E. Becker
J Biol Chem. 2020 Sep 4; 295(36): 12716–12726. Published online 2020 Jul 16. doi: 10.1074/jbc.RA120.012655
PMCID:
PMC7476715
AbstractArticlePDF–3.0M

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