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Select item 108671041.

Evolutionary conservation of putative suicidality-related risk genes that produce diminished motivation corrected by clozapine, lithium and antidepressants

Titilade Ajayi, Alicia Thomas, Marko Nikolic, Lauryn Henderson, Alexa Zaheri, Donard S. Dwyer

Front Psychiatry. 2024; 15: 1341735. Published online 2024 Feb 1. doi: 10.3389/fpsyt.2024.1341735

PMCID:: PMC10867104

Abstract Article PDF–4.8M

Select item 84425752.

Insulin/IGF-1 signaling and heat stress differentially regulate HSF1 activities in germline development

Stacey L. Edwards, Purevsuren Erdenebat, Allison C. Morphis, Lalit Kumar, Lai Wang, Tomasz Chamera, Constantin Georgescu, Jonathan D. Wren, Jian Li

Cell Rep. Author manuscript; available in PMC 2021 Sep 15.

Published in final edited form as: Cell Rep. 2021 Aug 31; 36(9): 109623. doi: 10.1016/j.celrep.2021.109623

PMCID:: PMC8442575

Abstract Article PDF–1.5M

Select item 73778483.

Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids

Steffen Möller, Nadine Saul, Alan A. Cohen, Rüdiger Köhling, Sina Sender, Hugo Murua Escobar, Christian Junghanss, Francesca Cirulli, Alessandra Berry, Peter Antal, Priit Adler, Jaak Vilo, Michele Boiani, Ludger Jansen, Dirk Repsilber, Hans Jörgen Grabe, Stephan Struckmann, Israel Barrantes, Mohamed Hamed, Brecht Wouters, Liliane Schoofs, Walter Luyten, Georg Fuellen

Aging (Albany NY) 2020 Jul 15; 12(13): 12534–12581. Published online 2020 Jul 7. doi: 10.18632/aging.103514

PMCID:: PMC7377848

Abstract Article PDF–2.1M

Select item 62165904.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 54780925.

Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species

Julie A. Hall, Matthew K. McElwee, Jonathan H. Freedman

PLoS One. 2017; 12(6): e0177432. Published online 2017 Jun 20. doi: 10.1371/journal.pone.0177432

PMCID:: PMC5478092

Abstract Article PDF–2.8M

Select item 48751096.

Insulin-like signaling pathway functions in integrative response to an olfactory and a gustatory stimuli in Caenorhabditis elegans

Ya-Ming Jiu, Yang Yue, Song Yang, Lin Liu, Jun-Wei Yu, Zheng-Xing Wu, Tao Xu

Protein Cell. 2010 Jan; 1(1): 75–81. Published online 2010 Feb 7. doi: 10.1007/s13238-010-0003-4

PMCID:: PMC4875109

Abstract Article PDF–776K

Select item 47833447.

Long live FOXO: unraveling the role of FOXO proteins in aging and longevity

Rute Martins, Gordon J. Lithgow, Wolfgang Link

Aging Cell. 2016 Apr; 15(2): 196–207. Published online 2015 Dec 8. doi: 10.1111/acel.12427

PMCID:: PMC4783344

Abstract Article PDF–329K

Select item 47815698.

Signaling in the immune response.

Jonathan J Ewbank

WormBook. 2006 : 1–12. Published online 2006 Jan 23. doi: 10.1895/wormbook.1.83.1

PMCID:: PMC4781569

Abstract Article

Select item 47809529.

Insulin/insulin-like growth factor signaling in C. elegans.

Coleen T Murphy, Patrick J Hu

WormBook. 2013 : 1–43. Published online 2013 Dec 26. doi: 10.1895/wormbook.1.164.1

PMCID:: PMC4780952

Abstract Article

Select item 478092910.

Genomic overview of protein kinases.

Gerard Manning

WormBook. 2005 : 1–19. Published online 2005 Dec 13. doi: 10.1895/wormbook.1.60.1

PMCID:: PMC4780929

Abstract Article

Select item 474102411.

Molecular characterization of the Haemonchus contortus phosphoinositide-dependent protein kinase-1 gene (Hc-pdk-1)

Fa-Cai Li, Robin B. Gasser, James B. Lok, Pasi K. Korhonen, Li He, Wen-Da Di, Fang-Yuan Yin, Rui Zhou, Yan-Qin Zhou, Jun-Long Zhao, Min Hu

Parasit Vectors. 2016; 9: 65. Published online 2016 Feb 3. doi: 10.1186/s13071-016-1351-6

PMCID:: PMC4741024

Abstract Article PDF–693K

Select item 468498812.

Insulin signaling genes modulate nicotine-induced behavioral responses in C. elegans

Seth A. Wescott, Elizabeth A. Ronan, X.Z. Shawn Xu

Behav Pharmacol. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Behav Pharmacol. 2016 Feb; 27(1): 44–49. doi: 10.1097/FBP.0000000000000186

PMCID:: PMC4684988

Abstract Article PDF–838K

Select item 451148213.

Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan

Kathleen J. Dumas, Chunfang Guo, Xi Wang, Kirk B. Burkhart, Elizabeth J. Adams, Hena Alam, Patrick J. Hu

Dev Biol. Author manuscript; available in PMC 2015 Jul 22.

Published in final edited form as: Dev Biol. 2010 Apr 15; 340(2): 605–612. Published online 2010 Feb 21. doi: 10.1016/j.ydbio.2010.02.022

PMCID:: PMC4511482

Abstract Article PDF–650K

Select item 440992814.

Mitochondrial maintenance failure in aging and role of sexual dimorphism

John Tower

Arch Biochem Biophys. Author manuscript; available in PMC 2016 Jun 15.

Published in final edited form as: Arch Biochem Biophys. 2015 Jun 15; 576: 17–31. Published online 2014 Oct 25. doi: 10.1016/j.abb.2014.10.008

PMCID:: PMC4409928

Abstract Article PDF–2.1M

Select item 424409115.

The Insulin/IGF Signaling Regulators Cytohesin/GRP-1 and PIP5K/PPK-1 Modulate Susceptibility to Excitotoxicity in C. elegans

Nazila Tehrani, John Del Rosario, Moises Dominguez, Robert Kalb, Itzhak Mano

PLoS One. 2014; 9(11): e113060. Published online 2014 Nov 25. doi: 10.1371/journal.pone.0113060

PMCID:: PMC4244091

Abstract Article PDF–1.1M

Select item 401248116.

Neuronal Migration Is Regulated by Endogenous RNAi and Chromatin-Binding Factor ZFP-1/AF10 in Caenorhabditis elegans

Lisa M. Kennedy, Alla Grishok

Genetics. 2014 May; 197(1): 207–220. Published online 2014 Feb 20. doi: 10.1534/genetics.114.162917

PMCID:: PMC4012481

Abstract Article PDF–2.2M

Select item 397911917.

The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans

Annette O. Estevez, Kathleen L. Morgan, Nathaniel J. Szewczyk, David Gems, Miguel Estevez

Neurotoxicology. 2014 Mar; 41(100): 28–43. doi: 10.1016/j.neuro.2013.12.012

PMCID:: PMC3979119

Abstract Article

Select item 368074218.

Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development

Wesley L Hung, Christine Hwang, ShangBang Gao, Edward H Liao, Jyothsna Chitturi, Ying Wang, Hang Li, Christian Stigloher, Jean-Louis Bessereau, Mei Zhen

EMBO J. 2013 Jun 12; 32(12): 1745–1760. Published online 2013 May 10. doi: 10.1038/emboj.2013.91

PMCID:: PMC3680742

Abstract Article PDF–2.1M

Select item 367022919.

Endogenous RNAi and adaptation to environment in C. elegans

Alla Grishok

Worm. 2012 Apr 1; 1(2): 129–133. doi: 10.4161/worm.19538

PMCID:: PMC3670229

Abstract Article PDF–263K

Select item 362308020.

The Conserved PHD1-PHD2 Domain of ZFP-1/AF10 Is a Discrete Functional Module Essential for Viability in Caenorhabditis elegans

Daphne C. Avgousti, Germano Cecere, Alla Grishok

Mol Cell Biol. 2013 Mar; 33(5): 999–1015. doi: 10.1128/MCB.01462-12

PMCID:: PMC3623080

Abstract Article PDF–4.3M

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