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Select item 109780271.

Tissue-specific silencing of integrated transgenes achieved through endogenous RNA interference in Caenorhabditis elegans

Siyu Chen, Weihong Liu, Lei Xiong, Zhiju Tao, Di Zhao

RNA Biol. 2024; 21(1): 1–10. Published online 2024 Mar 26. doi: 10.1080/15476286.2024.2332856

PMCID:: PMC10978027

Abstract Article PDF–2.2M

Select item 104832802.

Transcriptional repression during spermatogenesis in C. elegans requires TOP-2, condensin II, and the MET-2 H3K9 methyltransferase.

Emilie Chien, W. Matthew Michael

MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000933. Published online 2023 Aug 23. doi: 10.17912/micropub.biology.000933

PMCID:: PMC10483280

Abstract Article PDF–1.9M

Select item 103207663.

A transcriptional cofactor regulatory network for the C. elegans intestine

Brent B Horowitz, Shivani Nanda, Albertha J M Walhout

G3 (Bethesda) 2023 Jul; 13(7): jkad096. Published online 2023 Apr 29. doi: 10.1093/g3journal/jkad096

PMCID:: PMC10320766

Abstract Article PDF–1.9M

Select item 102333764.

A small RNA system ensures accurate homologous pairing and unpaired silencing of meiotic chromosomes

Hiroaki Tabara, Shohei Mitani, Megumi Mochizuki, Yuji Kohara, Kyosuke Nagata

EMBO J. 2023 Jun; 42(11): e105002. Published online 2023 Apr 20. doi: 10.15252/embj.2020105002

PMCID:: PMC10233376

Abstract Article PDF–2.9M

Select item 101131565.

The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities

Arturo Bujarrabal-Dueso, Georg Sendtner, David H. Meyer, Georgia Chatzinikolaou, Kalliopi Stratigi, George A. Garinis, Björn Schumacher

Nat Struct Mol Biol. 2023; 30(4): 475–488. Published online 2023 Mar 23. doi: 10.1038/s41594-023-00942-8

PMCID:: PMC10113156

Abstract Article PDF–13M

Select item 99915096.

SPR-1/CoREST facilitates the maternal epigenetic reprogramming of the histone demethylase SPR-5/LSD1

Brandon S Carpenter, Alyssa Scott, Robert Goldin, Sindy R Chavez, Juan D Rodriguez, Dexter A Myrick, Marcus Curlee, Karen L Schmeichel, David J Katz

Genetics. 2023 Mar; 223(3): iyad005. Published online 2023 Jan 19. doi: 10.1093/genetics/iyad005

PMCID:: PMC9991509

Abstract Article PDF–1.2M

Select item 99888417.

Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in C. elegans

Xinhao Hou, Mingjing Xu, Chengming Zhu, Jianing Gao, Meili Li, Xiangyang Chen, Cheng Sun, Björn Nashan, Jianye Zang, Ying Zhou, Shouhong Guang, Xuezhu Feng

Nat Commun. 2023; 14: 1254. Published online 2023 Mar 6. doi: 10.1038/s41467-023-36898-y

PMCID:: PMC9988841

Abstract Article PDF–21M

Select item 99078188.

Chromatin landscape, DSB levels, and cKU-70/80 contribute to patterning of meiotic DSB processing along chromosomes in C. elegans

Laura I. Lascarez-Lagunas, Marina Martinez-Garcia, Saravanapriah Nadarajan, Brianna N. Diaz-Pacheco, Elizaveta Berson, Mónica P. Colaiácovo

PLoS Genet. 2023 Jan; 19(1): e1010627. Published online 2023 Jan 27. doi: 10.1371/journal.pgen.1010627

PMCID:: PMC9907818

Abstract Article PDF–3.6M

Select item 97984729.

Reprogramming the piRNA pathway for multiplexed and transgenerational gene silencing in C. elegans

Monika Priyadarshini, Julie Zhouli Ni, Amhed M. Vargas-Velazquez, Sam Guoping Gu, Christian Frøkjær-Jensen

Nat Methods. Author manuscript; available in PMC 2022 Dec 29.

Published in final edited form as: Nat Methods. 2022 Feb; 19(2): 187–194. Published online 2022 Feb 3. doi: 10.1038/s41592-021-01369-z

PMCID:: PMC9798472

Abstract Article PDF–4.2M

Select item 951484910.

H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans

Meng Huang, Minjie Hong, Xinhao Hou, Chengming Zhu, Di Chen, Xiangyang Chen, Shouhong Guang, Xuezhu Feng

eLife. 2022; 11: e74812. Published online 2022 Sep 20. doi: 10.7554/eLife.74812

PMCID:: PMC9514849

Abstract Article PDF–2.1M

Select item 937190111.

R-loop-induced irreparable DNA damage evades checkpoint detection in the C. elegans germline

Tara Hicks, Emily Koury, Caleb McCabe, Cameron Williams, Caroline Crahan, Sarit Smolikove

Nucleic Acids Res. 2022 Aug 12; 50(14): 8041–8059. Published online 2022 Jul 25. doi: 10.1093/nar/gkac621

PMCID:: PMC9371901

Abstract Article PDF–8.9M

Select item 907152912.

The zinc-finger transcription factor LSL-1 is a major regulator of the germline transcriptional program in Caenorhabditis elegans

David Rodriguez-Crespo, Magali Nanchen, Shweta Rajopadhye, Chantal Wicky

Genetics. 2022 May; 221(1): iyac039. Published online 2022 Mar 9. doi: 10.1093/genetics/iyac039

PMCID:: PMC9071529

Abstract Article PDF–2.5M

Select item 885019213.

SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity

Colin E. Delaney, Stephen P. Methot, Veronique Kalck, Jan Seebacher, Daniel Hess, Susan M. Gasser, Jan Padeken

Nat Struct Mol Biol. 2022; 29(2): 85–96. Published online 2022 Jan 31. doi: 10.1038/s41594-021-00712-4

Correction in:: Nat Struct Mol Biol. 2022; 29(5): 502.

PMCID:: PMC8850192

Abstract Article PDF–9.8M

Select item 864228814.

Gene bookmarking by the heat-shock transcription factor programs the insulin-like signaling pathway

Srijit Das, Sehee Min, Veena Prahlad

Mol Cell. Author manuscript; available in PMC 2022 Dec 2.

Published in final edited form as: Mol Cell. 2021 Oct 5 : S1097-2765(21)00775-9. Published online 2021 Oct 5. doi: 10.1016/j.molcel.2021.09.022

PMCID:: PMC8642288

Abstract Article PDF–2.4M

Select item 857272515.

H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity

Stephen P. Methot, Jan Padeken, Giovanna Brancati, Peter Zeller, Colin E. Delaney, Dimos Gaidatzis, Hubertus Kohler, Alexander van Oudenaarden, Helge Großhans, Susan M. Gasser

Nat Cell Biol. 2021; 23(11): 1163–1175. Published online 2021 Nov 4. doi: 10.1038/s41556-021-00776-w

PMCID:: PMC8572725

Abstract Article PDF–9.0M

Select item 850177916.

The nuclear ubiquitin ligase adaptor SPOP is a conserved regulator of C9orf72 dipeptide toxicity

Carley Snoznik, Valentina Medvedeva, Jelena Mojsilovic-Petrovic, Paige Rudich, James Oosten, Robert G. Kalb, Todd Lamitina

Proc Natl Acad Sci U S A. 2021 Oct 5; 118(40): e2104664118. Published online 2021 Sep 30. doi: 10.1073/pnas.2104664118

PMCID:: PMC8501779

Abstract Article PDF–1.5M

Select item 833118317.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833