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Select item 110046821.

A DNA nanodevice for mapping sodium at single organelle resolution

Junyi Zou, Koushambi Mitra, Palapuravan Anees, Daphne Oettinger, Joseph Ramirez, Aneesh Tazhe Veetil, Priyanka Dutta Gupta, Rajini Rao, Jayson J. Smith, Paschalis Kratsios, Yamuna Krishnan

Nat Biotechnol. Author manuscript; available in PMC 2024 Jul 17.

Published in final edited form as: Nat Biotechnol. 2024 Jul; 42(7): 1075–1083. Published online 2023 Sep 21. doi: 10.1038/s41587-023-01950-1

PMCID:: PMC11004682

Abstract Article PDF–3.3M

Select item 106176262.

SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans

Valerie J. Robert, Matthieu Caron, Loic Gely, Annie Adrait, Victoria Pakulska, Yohann Couté, Manon Chevalier, Christian G. Riedel, Cecile Bedet, Francesca Palladino

Development. 2023 Nov 1; 150(21): dev201755. Published online 2023 Oct 17. doi: 10.1242/dev.201755

PMCID:: PMC10617626

Abstract Article

Select item 103356763.

Partial inhibition of class III PI3K VPS-34 ameliorates motor aging and prolongs health span

Zhongliang Hu, Yamei Luo, Yuting Liu, Yaru Luo, Liangce Wang, Shengsong Gou, Yuling Peng, Rui Wei, Da Jia, Yuan Wang, Shangbang Gao, Yan Zhang

PLoS Biol. 2023 Jul; 21(7): e3002165. Published online 2023 Jul 11. doi: 10.1371/journal.pbio.3002165

PMCID:: PMC10335676

Abstract Article PDF–2.2M

Select item 101679954.

The dynamin GTPase mediates regenerative axonal fusion in Caenorhabditis elegans by regulating fusogen levels

Tarika Vijayaraghavan, Samiksha Dhananjay, Xue Yan Ho, Rosina Giordano-Santini, Massimo Hilliard, Brent Neumann

PNAS Nexus. 2023 May; 2(5): pgad114. Published online 2023 May 9. doi: 10.1093/pnasnexus/pgad114

PMCID:: PMC10167995

Abstract Article PDF–5.1M

Select item 101053285.

Yolk-deprived Caenorhabditis elegans secure brood size at the expense of competitive fitness

Ellen Geens, Pieter Van de Walle, Francesca Caroti, Rob Jelier, Christian Steuwe, Liliane Schoofs, Liesbet Temmerman

Life Sci Alliance. 2023 Jun; 6(6): e202201675. Published online 2023 Apr 14. doi: 10.26508/lsa.202201675

PMCID:: PMC10105328

Abstract Article PDF–2.0M

Select item 100140666.

Endosomal trafficking protein TBC‐2 modulates stress resistance and lifespan through DAF‐16‐dependent and independent mechanisms

Annika Traa, Sonja K. Soo, Abdelrahman AlOkda, Bokang Ko, Christian E. Rocheleau, Jeremy M. Van Raamsdonk

Aging Cell. 2023 Mar; 22(3): e13762. Published online 2023 Feb 15. doi: 10.1111/acel.13762

PMCID:: PMC10014066

Abstract Article PDF–6.4M

Select item 99920957.

A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes

Gholamreza Fazeli, Roni Levin-Konigsberg, Michael C. Bassik, Christian Stigloher, Ann M. Wehman

Curr Biol. Author manuscript; available in PMC 2024 Feb 27.

Published in final edited form as: Curr Biol. 2023 Feb 27; 33(4): 607–621.e7. Published online 2023 Jan 17. doi: 10.1016/j.cub.2022.12.041

PMCID:: PMC9992095

Abstract Article PDF–2.5M

Select item 98854408.

Intracellular lipid surveillance by small G protein geranylgeranylation

Abigail Watterson, Lexus Tatge, Naureen Wajahat, Sonja L. B. Arneaud, Rene Solano Fonseca, Shaghayegh T. Beheshti, Patrick Metang, Melina Mihelakis, Kielen R. Zuurbier, Chase D. Corley, Ishmael Dehghan, Jeffrey G. McDonald, Peter M. Douglas

Nature. Author manuscript; available in PMC 2023 Jan 30.

Published in final edited form as: Nature. 2022 May; 605(7911): 736–740. Published online 2022 May 18. doi: 10.1038/s41586-022-04729-7

PMCID:: PMC9885440

Abstract Article PDF–4.2M

Select item 96420769.

Loss of heat shock factor initiates intracellular lipid surveillance by actin destabilization

Abigail Watterson, Sonja L.B. Arneaud, Naureen Wajahat, Jordan M. Wall, Lexus Tatge, Shaghayegh T. Beheshti, Melina Mihelakis, Nicholas Y. Cheatwood, Jacob McClendon, Atossa Ghorashi, Ishmael Dehghan, Chase D. Corley, Jeffrey G. McDonald, Peter M. Douglas

Cell Rep. Author manuscript; available in PMC 2022 Nov 8.

Published in final edited form as: Cell Rep. 2022 Oct 18; 41(3): 111493. doi: 10.1016/j.celrep.2022.111493

PMCID:: PMC9642076

Abstract Article PDF–1.6M

Select item 947089510.

Reduced bone morphogenic protein signaling along the gut–neuron axis by heat shock factor promotes longevity

Sonja L. B. Arneaud, Jacob McClendon, Lexus Tatge, Abigail Watterson, Kielen R. Zuurbier, Bhoomi Madhu, Tina L. Gumienny, Peter M. Douglas

Aging Cell. 2022 Sep; 21(9): e13693. Published online 2022 Aug 17. doi: 10.1111/acel.13693

PMCID:: PMC9470895

Abstract Article PDF–6.4M

Select item 943784811.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 937135612.

The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespan

İçten Meraş, Laëtitia Chotard, Thomas Liontis, Zakaria Ratemi, Benjamin Wiles, Jung Hwa Seo, Jeremy M. Van Raamsdonk, Christian E. Rocheleau

PLoS Genet. 2022 Aug; 18(8): e1010328. Published online 2022 Aug 1. doi: 10.1371/journal.pgen.1010328

PMCID:: PMC9371356

Abstract Article PDF–3.3M

Select item 923309313.

A cilia-independent function of BBSome mediated by DLK MAPK signaling in C. elegans photosensation

Xinxing Zhang, Jinzhi Liu, Tong Pan, Alex Ward, Jianfeng Liu, X.Z. Shawn Xu

Dev Cell. Author manuscript; available in PMC 2023 Jun 20.

Published in final edited form as: Dev Cell. 2022 Jun 20; 57(12): 1545–1557.e4. Published online 2022 May 31. doi: 10.1016/j.devcel.2022.05.005

PMCID:: PMC9233093

Abstract Article PDF–1.1M

Select item 912992214.

SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion

Xianghong Wang, Xinxin Li, Junkai Wang, Jiabin Wang, Can Hu, Jia Zeng, Anbing Shi, Long Lin

J Cell Biol. 2022 Jul 4; 221(7): e202111125. Published online 2022 May 23. doi: 10.1083/jcb.202111125

PMCID:: PMC9129922

Abstract Article PDF–8.5M

Select item 883296815.

A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C

Huiyan Huang, Jiehong Pan, David R. Spielberg, Neil A. Hanchard, Daryl A. Scott, Lindsay C. Burrage, Hongzheng Dai, David Murdock, Jill A. Rosenfeld, Ariz Mohammad, Tao Huang, Anika G. Lindsey, Hyori Kim, Jian Chen, Avinash Ramu, Stephanie A. Morrison, Zachary D. Dawson, Alex Z. Hu, Eric Tycksen, Gary A. Silverman, Dustin Baldridge, Jennifer A. Wambach, Undiagnosed Diseases Network, Stephen C. Pak, Steven L. Brody, Tim Schedl

Proc Natl Acad Sci U S A. 2022 Feb 8; 119(6): e2105228119. Published online 2022 Feb 4. doi: 10.1073/pnas.2105228119

PMCID:: PMC8832968

Abstract Article PDF–2.4M

Select item 866510116.

Asymmetric organelle positioning during epithelial polarization of C. elegans intestinal cells

James N. Brandt, Laura Voss, Fiona M. Rambo, Katelyn Nicholson, Jackson R. Thein, Lydia Fairchild, Laurence Seabrook, Danielia Lewis, Lali Guevara-Hernandez, Matthew L. White, Luca Sax, Victoria Eichten, Logan Harper, Greg J. Hermann

Dev Biol. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Dev Biol. 2022 Jan; 481: 75–94. Published online 2021 Sep 29. doi: 10.1016/j.ydbio.2021.09.007

PMCID:: PMC8665101

Abstract Article PDF–5.3M

Select item 852371817.

PDZD-8 and TEX-2 regulate endosomal PI(4,5)P₂ homeostasis via lipid transport to promote embryogenesis in C. elegans

Darshini Jeyasimman, Bilge Ercan, Dennis Dharmawan, Tomoki Naito, Jingbo Sun, Yasunori Saheki

Nat Commun. 2021; 12: 6065. Published online 2021 Oct 18. doi: 10.1038/s41467-021-26177-z

PMCID:: PMC8523718

Abstract Article PDF–8.7M

Select item 844679318.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 833118319.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 804789420.

RTKN-1/Rhotekin shields endosome-associated F-actin from disassembly to ensure endocytic recycling

Yanling Yan, Shuai Liu, Can Hu, Chaoyi Xie, Linyue Zhao, Shimin Wang, Wenjuan Zhang, Zihang Cheng, Jinghu Gao, Xin Fu, Zhenrong Yang, Xianghong Wang, Jing Zhang, Long Lin, Anbing Shi

J Cell Biol. 2021 May 3; 220(5): e202007149. Published online 2021 Apr 12. doi: 10.1083/jcb.202007149

PMCID:: PMC8047894

Abstract Article PDF–9.9M

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