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Select item 105234691.

An intraflagellar transport dependent negative feedback regulates the MAPKKK DLK-1 to protect cilia from degeneration

Yue Sun, Yishi Jin

Proc Natl Acad Sci U S A. 2023 Sep 26; 120(39): e2302801120. Published online 2023 Sep 18. doi: 10.1073/pnas.2302801120

PMCID:: PMC10523469

Abstract Article PDF–2.4M

Select item 103932962.

Forkhead transcription factor FKH-8 cooperates with RFX in the direct regulation of sensory cilia in Caenorhabditis elegans

Rebeca Brocal-Ruiz, Ainara Esteve-Serrano, Carlos Mora-Martínez, Maria Luisa Franco-Rivadeneira, Peter Swoboda, Juan J Tena, Marçal Vilar, Nuria Flames

eLife. 2023; 12: e89702. Published online 2023 Jul 14. doi: 10.7554/eLife.89702

PMCID:: PMC10393296

Abstract Article PDF–10M

Select item 100837263.

The sensory cilia of Caenorhabditis elegans.

Peter N Inglis, Guangshuo Ou, Michel R Leroux, Jonathan M Scholey

WormBook. 2007 Mar 8 : 1–22. Published online 2007 Mar 8. doi: 10.1895/wormbook.1.126.2

PMCID:: PMC10083726

Abstract Article

Select item 99580704.

Microfluidics and fluorescence microscopy protocol to study the response of C. elegans to chemosensory stimuli

Christine W. Bruggeman, Guus H. Haasnoot, Erwin J.G. Peterman

STAR Protoc. 2023 Mar 17; 4(1): 102121. Published online 2023 Feb 14. doi: 10.1016/j.xpro.2023.102121

PMCID:: PMC9958070

Abstract Article PDF–2.8M

Select item 89623815.

Aripiprazole Offsets Mutant ATXN3-Induced Motor Dysfunction by Targeting Dopamine D₂ and Serotonin 1A and 2A Receptors in C. elegans

Ana Jalles, Cármen Vieira, Joana Pereira-Sousa, Daniela Vilasboas-Campos, Ana Francisca Mota, Sara Vasconcelos, Bruna Ferreira-Lomba, Marta Daniela Costa, Jorge Diogo Da Silva, Patrícia Maciel, Andreia Teixeira-Castro

Biomedicines. 2022 Feb; 10(2): 370. Published online 2022 Feb 3. doi: 10.3390/biomedicines10020370

PMCID:: PMC8962381

Abstract Article PDF–22M

Select item 86093186.

Direct imaging of intraflagellar-transport turnarounds reveals that motors detach, diffuse, and reattach to opposite-direction trains

Zhiqing Zhang, Noémie Danné, Bonno Meddens, Iddo Heller, Erwin J. G. Peterman

Proc Natl Acad Sci U S A. 2021 Nov 9; 118(45): e2115089118. Published online 2021 Nov 3. doi: 10.1073/pnas.2115089118

PMCID:: PMC8609318

Abstract Article PDF–2.0M

Select item 85768717.

WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing

Ana R.G. De-Castro, Diogo R.M. Rodrigues, Maria J.G. De-Castro, Neide Vieira, Cármen Vieira, Ana X. Carvalho, Reto Gassmann, Carla M.C. Abreu, Tiago J. Dantas

J Cell Biol. 2022 Jan 3; 221(1): e202010178. Published online 2021 Nov 5. doi: 10.1083/jcb.202010178

PMCID:: PMC8576871

Abstract Article PDF–8.1M

Select item 79561628.

GRDN-1/Girdin regulates dendrite morphogenesis and cilium position in two specialized sensory neuron types in C. elegans

Inna Nechipurenko, Sofia Lavrentyeva, Piali Sengupta

Dev Biol. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Dev Biol. 2021 Apr; 472: 38–51. Published online 2021 Jan 16. doi: 10.1016/j.ydbio.2020.12.022

PMCID:: PMC7956162

Abstract Article PDF–1.3M

Select item 78597019.

Interpreting the pathogenicity of Joubert syndrome missense variants in Caenorhabditis elegans

Karen I. Lange, Sofia Tsiropoulou, Katarzyna Kucharska, Oliver E. Blacque

Dis Model Mech. 2021 Jan 1; 14(1): dmm046631. Published online 2021 Jan 26. doi: 10.1242/dmm.046631

PMCID:: PMC7859701

Abstract Article

Select item 718379410.

Cutting off ciliary protein import: intraflagellar transport after dendritic femtosecond-laser ablation

Jona Mijalkovic, Jules Girard, Jaap van Krugten, Jasmijn van Loo, Zhiqing Zhang, Elizaveta Loseva, Felix Oswald, Erwin J. G. Peterman

Mol Biol Cell. 2020 Mar 1; 31(5): 324–334. doi: 10.1091/mbc.E18-06-0399

PMCID:: PMC7183794

Abstract Article PDF–4.2M

Select item 621659011.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 584685912.

CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function

Peter Canning, Kwangjin Park, João Gonçalves, Chunmei Li, Conor J. Howard, Timothy D. Sharpe, Liam J. Holt, Laurence Pelletier, Alex N. Bullock, Michel R. Leroux

Cell Rep. 2018 Jan 23; 22(4): 885–894. Published online 2018 Jan 28. doi: 10.1016/j.celrep.2017.12.083

PMCID:: PMC5846859

Abstract Article PDF–4.1M

Select item 514514413.

Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport

Victor L. Jensen, Stephen Carter, Anna A. W. M. Sanders, Chunmei Li, Julie Kennedy, Tiffany A. Timbers, Jerry Cai, Noemie Scheidel, Breandán N. Kennedy, Ryan D. Morin, Michel R. Leroux, Oliver E. Blacque

PLoS Genet. 2016 Dec; 12(12): e1006469. Published online 2016 Dec 8. doi: 10.1371/journal.pgen.1006469

PMCID:: PMC5145144

Abstract Article PDF–2.9M

Select item 502306814.

A conserved role for Girdin in basal body positioning and ciliogenesis

Inna V. Nechipurenko, Anique Olivier-Mason, Anna Kazatskaya, Julie Kennedy, Ian G. McLachlan, Maxwell G. Heiman, Oliver E. Blacque, Piali Sengupta

Dev Cell. Author manuscript; available in PMC 2017 Sep 12.

Published in final edited form as: Dev Cell. 2016 Sep 12; 38(5): 493–506. doi: 10.1016/j.devcel.2016.07.013

PMCID:: PMC5023068

Abstract Article PDF–2.2M

Select item 499214015.

The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gate

Qing Wei, Yingyi Zhang, Clementine Schouteden, Yuxia Zhang, Qing Zhang, Jinhong Dong, Veronika Wonesch, Kun Ling, Alexander Dammermann, Jinghua Hu

Nat Commun. 2016; 7: 12437. Published online 2016 Aug 18. doi: 10.1038/ncomms12437

PMCID:: PMC4992140

Abstract Article PDF–2.4M

Select item 479424716.

MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone

Chunmei Li, Victor L. Jensen, Kwangjin Park, Julie Kennedy, Francesc R. Garcia-Gonzalo, Marta Romani, Roberta De Mori, Ange-Line Bruel, Dominique Gaillard, Bérénice Doray, Estelle Lopez, Jean-Baptiste Rivière, Laurence Faivre, Christel Thauvin-Robinet, Jeremy F. Reiter, Oliver E. Blacque, Enza Maria Valente, Michel R. Leroux

PLoS Biol. 2016 Mar; 14(3): e1002416. Published online 2016 Mar 16. doi: 10.1371/journal.pbio.1002416

PMCID:: PMC4794247

Abstract Article PDF–8.5M

Select item 474966417.

A Screen for Modifiers of Cilia Phenotypes Reveals Novel MKS Alleles and Uncovers a Specific Genetic Interaction between osm-3 and nphp-4

Svetlana V. Masyukova, Dawn E. Landis, Scott J. Henke, Corey L. Williams, Jay N. Pieczynski, Kelly N. Roszczynialski, Jannese E. Covington, Erik B. Malarkey, Bradley K. Yoder

PLoS Genet. 2016 Feb; 12(2): e1005841. Published online 2016 Feb 10. doi: 10.1371/journal.pgen.1005841

PMCID:: PMC4749664

Abstract Article PDF–6.6M

Select item 439549418.

TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone

Elle C. Roberson, William E. Dowdle, Aysegul Ozanturk, Francesc R. Garcia-Gonzalo, Chunmei Li, Jan Halbritter, Nadia Elkhartoufi, Jonathan D. Porath, Heidi Cope, Allison Ashley-Koch, Simon Gregory, Sophie Thomas, John A. Sayer, Sophie Saunier, Edgar A. Otto, Nicholas Katsanis, Erica E. Davis, Tania Attié-Bitach, Friedhelm Hildebrandt, Michel R. Leroux, Jeremy F. Reiter

J Cell Biol. 2015 Apr 13; 209(1): 129–142. doi: 10.1083/jcb.201411087

PMCID:: PMC4395494

Abstract Article PDF–2.8M

Select item 426574219.

Ciliopathy proteins establish a bipartite signaling compartment in a C. elegans thermosensory neuron

Phuong Anh T. Nguyen, Willisa Liou, David H. Hall, Michel R. Leroux

J Cell Sci. 2014 Dec 15; 127(24): 5317–5330. doi: 10.1242/jcs.157610

PMCID:: PMC4265742

Abstract Article

Select item 367897220.

ENDOCYTOSIS GENES FACILITATE PROTEIN AND MEMBRANE TRANSPORT IN C. ELEGANS SENSORY CILIA

Oktay I. Kaplan, David B. Doroquez, Sebiha Cevik, Rachel V. Bowie, Lara Clarke, Anna A.W.M. Sanders, Katarzyna Kida, Joshua Z. Rappoport, Piali Sengupta, Oliver E. Blacque

Curr Biol. Author manuscript; available in PMC 2013 Jun 11.

Published in final edited form as: Curr Biol. 2012 Mar 20; 22(6): 451–460. Published online 2012 Feb 16. doi: 10.1016/j.cub.2012.01.060