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Select item 108282691.

In-vivo screening implicates endoribonuclease Regnase-1 in modulating senescence-associated lysosomal changes

Richard Venz, Anita Goyala, Abel Soto-Gamez, Tugce Yenice, Marco Demaria, Collin Y. Ewald

GeroScience. 2024 Apr; 46(2): 1499–1514. Published online 2023 Aug 29. doi: 10.1007/s11357-023-00909-z

PMCID:: PMC10828269

Abstract Article PDF–3.0M

Select item 106209052.

A gonadal gap junction INX-14/Notch GLP-1 signaling axis suppresses gut defense through an intestinal lysosome pathway

Xiumei Zhang, Yirong Wang, Zixin Cai, Zhiqing Wan, Yilixiati Aihemaiti, Haijun Tu

Front Immunol. 2023; 14: 1249436. Published online 2023 Oct 19. doi: 10.3389/fimmu.2023.1249436

PMCID:: PMC10620905

Abstract Article PDF–6.5M

Select item 105235843.

LST-1 is a bifunctional regulator that feeds back on Notch-dependent transcription to regulate C. elegans germline stem cells

Ahlan S. Ferdous, Tina R. Lynch, Stephany J. Costa Dos Santos, Deep H. Kapadia, Sarah L. Crittenden, Judith Kimble

Proc Natl Acad Sci U S A. 2023 Sep 26; 120(39): e2309964120. Published online 2023 Sep 20. doi: 10.1073/pnas.2309964120

PMCID:: PMC10523584

Abstract Article PDF–1.7M

Select item 105201734.

The effect of GLP-1 receptor agonist lixisenatide on experimental diabetic retinopathy

Kuebra Oezer, Matthias Kolibabka, Johann Gassenhuber, Nadine Dietrich, Thomas Fleming, Andrea Schlotterer, Michael Morcos, Paulus Wohlfart, Hans-Peter Hammes

Acta Diabetol. 2023; 60(11): 1551–1565. Published online 2023 Jul 9. doi: 10.1007/s00592-023-02135-7

PMCID:: PMC10520173

Abstract Article PDF–1.7M

Select item 104574635.

CaMKII mediates sexually dimorphic synaptic transmission at neuromuscular junctions in C. elegans

Wan-Xin Zeng, Haowen Liu, Yue Hao, Kang-Ying Qian, Fu-Min Tian, Lei Li, Bin Yu, Xian-Ting Zeng, Shangbang Gao, Zhitao Hu, Xia-Jing Tong

J Cell Biol. 2023 Nov 6; 222(11): e202301117. Published online 2023 Aug 25. doi: 10.1083/jcb.202301117

PMCID:: PMC10457463

Abstract Article PDF–6.8M

Select item 104482126.

Preparation of low molecular weight polysaccharides from Tremella fuciformis by ultrasonic-assisted H₂O₂-Vc method: Structural characteristics, in vivo antioxidant activity and stress resistance

Quancen Lee, Xianjing Han, Mingfeng Zheng, Feng Lv, Bin Liu, Feng Zeng

Ultrason Sonochem. 2023 Oct; 99: 106555. Published online 2023 Aug 9. doi: 10.1016/j.ultsonch.2023.106555

PMCID:: PMC10448212

Abstract Article PDF–3.2M

Select item 102596597.

The in vivo functional significance of PUF hub partnerships in C. elegans germline stem cells

Ahlan S. Ferdous, Stephany J. Costa Dos Santos, Charlotte R. Kanzler, Heaji Shin, Brian H. Carrick, Sarah L. Crittenden, Marvin Wickens, Judith Kimble

Development. 2023 May 1; 150(9): dev201705. Published online 2023 May 9. doi: 10.1242/dev.201705

PMCID:: PMC10259659

Abstract Article

Select item 99220298.

TRIM-NHL protein, NHL-2, modulates cell fate choices in the C. elegans germ line

John L. Brenner, Erin M. Jyo, Ariz Mohammad, Paul Fox, Vovanti Jones, Elaine Mardis, Tim Schedl, Eleanor M. Maine

Dev Biol. Author manuscript; available in PMC 2023 Feb 11.

Published in final edited form as: Dev Biol. 2022 Nov; 491: 43–55. Published online 2022 Sep 3. doi: 10.1016/j.ydbio.2022.08.010

PMCID:: PMC9922029

Abstract Article PDF–2.5M

Select item 98427659.

The metabolite alpha-ketobutyrate extends lifespan by promoting peroxisomal function in C. elegans

Nan Wu, Yi-Cheng Ma, Xin-Qian Gong, Pei-Ji Zhao, Yong-Jian Jia, Qiu Zhao, Jia-Hong Duan, Cheng-Gang Zou

Nat Commun. 2023; 14: 240. Published online 2023 Jan 16. doi: 10.1038/s41467-023-35899-1

PMCID:: PMC9842765

Abstract Article PDF–2.8M

Select item 983761210.

Topoisomerases I and II facilitate condensin DC translocation to organize and repress X chromosomes in C. elegans

Ana Karina Morao, Jun Kim, Daniel Obaji, Siyu Sun, Sevinc Ercan

Mol Cell. Author manuscript; available in PMC 2023 Nov 17.

Published in final edited form as: Mol Cell. 2022 Nov 17; 82(22): 4202–4217.e5. Published online 2022 Oct 26. doi: 10.1016/j.molcel.2022.10.002

PMCID:: PMC9837612

Abstract Article PDF–3.0M

Select item 979008011.

Functional divergence of orthologous temperature-sensitive mutations in C. elegans and C. briggsae

Satheeja Santhi Velayudhan, Ronald E Ellis

MicroPubl Biol. 2022; 2022: 10.17912/micropub.biology.000705. Published online 2022 Dec 9. doi: 10.17912/micropub.biology.000705

PMCID:: PMC9790080

Abstract Article PDF–5.9M

Select item 975608912.

om92 , a glp-1 enhancer mutation, is an allele of ekl-1

Samantha A. Stein, Olivia F. Zucaro, Harold E. Smith, Kevin F. O'Connell, Jill M. Spoerke, Eleanor M. Maine, James L. Lissemore

MicroPubl Biol. 2022; 2022: 10.17912/micropub.biology.000698. Published online 2022 Nov 30. doi: 10.17912/micropub.biology.000698

PMCID:: PMC9756089

Abstract Article PDF–3.0M

Select item 968884413.

Further Extension of Lifespan by Unc-43/CaMKII and Egl-8/PLCβ Mutations in Germline-Deficient Caenorhabditis elegans

Hildegard I. D. Mack, Laura G. Buck, Sonja Skalet, Jennifer Kremer, Hao Li, Elisabeth K. M. Mack

Cells. 2022 Nov; 11(22): 3527. Published online 2022 Nov 8. doi: 10.3390/cells11223527

PMCID:: PMC9688844

Abstract Article PDF–2.1M

Select item 956363514.

Mutant C. elegans p53 Together with Gain-of-Function GLP-1/Notch Decreases UVC-Damage-Induced Germline Cell Death but Increases PARP Inhibitor-Induced Germline Cell Death

Jorge Canar, Prima Manandhar-Sasaki, Jill Bargonetti

Cancers (Basel) 2022 Oct; 14(19): 4929. Published online 2022 Oct 8. doi: 10.3390/cancers14194929

PMCID:: PMC9563635

Abstract Article PDF–2.4M

Select item 947374815.

SALSA, a genetically-encoded biosensor for spatiotemporal quantification of Notch signal transduction in vivo

Justin M. Shaffer, Iva Greenwald

Dev Cell. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Dev Cell. 2022 Apr 11; 57(7): 930–944.e6. doi: 10.1016/j.devcel.2022.03.008

PMCID:: PMC9473748

Abstract Article PDF–2.3M

Select item 947368916.

Innexin function dictates the spatial relationship between distal somatic cells in the Caenorhabditis elegans gonad without impacting the germline stem cell pool

Theadora Tolkin, Ariz Mohammad, Todd A Starich, Ken CQ Nguyen, David H Hall, Tim Schedl, E Jane Albert Hubbard, David Greenstein

eLife. 2022; 11: e74955. Published online 2022 Sep 13. doi: 10.7554/eLife.74955

PMCID:: PMC9473689

Abstract Article PDF–8.4M

Select item 938923717.

Exendin-4 alleviates β-Amyloid peptide toxicity via DAF-16 in a Caenorhabditis elegans model of Alzheimer's disease

Xiangwei Song, Yingqi Sun, Zhun Wang, Yingying Su, Yangkun Wang, Xueli Wang

Front Aging Neurosci. 2022; 14: 955113. Published online 2022 Aug 5. doi: 10.3389/fnagi.2022.955113

PMCID:: PMC9389237

Abstract Article PDF–2.1M

Select item 921028718.

A sensitized genetic screen to identify regulators of Caenorhabditis elegans germline stem cells

Sarah Robinson-Thiewes, Aaron M Kershner, Heaji Shin, Kimberly A Haupt, Peggy Kroll-Connor, Judith Kimble

G3 (Bethesda) 2022 Mar; 12(3): jkab439. Published online 2021 Dec 23. doi: 10.1093/g3journal/jkab439

PMCID:: PMC9210287

Abstract Article PDF–1.3M

Select item 918761219.

Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes

Mericien Venzon, Ritika Das, Daniel J. Luciano, Julia Burnett, Hyun Shin Park, Joseph Cooper Devlin, Eric T. Kool, Joel G. Belasco, E. Jane Albert Hubbard, Ken Cadwell

Cell Host Microbe. Author manuscript; available in PMC 2023 Jun 8.

Published in final edited form as: Cell Host Microbe. 2022 Jun 8; 30(6): 786–797.e8. Published online 2022 Apr 11. doi: 10.1016/j.chom.2022.03.015

PMCID:: PMC9187612

Abstract Article PDF–1.8M

Select item 917078320.

SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells

Joshua Jackson, Lena Wischhof, Enzo Scifo, Anna Pellizzer, Yiru Wang, Antonia Piazzesi, Debora Gentile, Sana Siddig, Miriam Stork, Chris E. Hopkins, Kristian Händler, Joachim Weis, Andreas Roos, Joachim L. Schultze, Pierluigi Nicotera, Dan Ehninger, Daniele Bano

Mol Metab. 2022 Jul; 61: 101503. Published online 2022 Apr 19. doi: 10.1016/j.molmet.2022.101503