PMC Links for GEO Profiles (Select 99437299) - PMC

Select item 97415041.

Reprograming of proteasomal degradation by branched chain amino acid metabolism

Sonia Ravanelli, Qiaochu Li, Andrea Annibal, Aleksandra Trifunovic, Adam Antebi, Thorsten Hoppe

Aging Cell. 2022 Dec; 21(12): e13725. Published online 2022 Sep 27. doi: 10.1111/acel.13725

PMCID:: PMC9741504

Select item 94378482.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 87531223.

Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes

Manusnan Suriyalaksh, Celia Raimondi, Abraham Mains, Anne Segonds-Pichon, Shahzabe Mukhtar, Sharlene Murdoch, Rebeca Aldunate, Felix Krueger, Roger Guimerà, Simon Andrews, Marta Sales-Pardo, Olivia Casanueva

iScience. 2022 Jan 21; 25(1): 103663. Published online 2021 Dec 20. doi: 10.1016/j.isci.2021.103663

PMCID:: PMC8753122

Abstract Article PDF–4.6M

Select item 84467934.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 84039225.

Genome-wide screen identifies curli amyloid fibril as a bacterial component promoting host neurodegeneration

Chenyin Wang, Chun Yin Lau, Fuqiang Ma, Chaogu Zheng

Proc Natl Acad Sci U S A. 2021 Aug 24; 118(34): e2106504118. Published online 2021 Aug 19. doi: 10.1073/pnas.2106504118

Correction in:: Proc Natl Acad Sci U S A. 2021 Oct 12; 118(41): e2116257118.

PMCID:: PMC8403922

Abstract Article PDF–2.5M

Select item 81902936.

Regulation of the one carbon folate cycle as a shared metabolic signature of longevity

Andrea Annibal, Rebecca George Tharyan, Maribel Fides Schonewolff, Hannah Tam, Christian Latza, Markus Max Karl Auler, Sebastian Grönke, Linda Partridge, Adam Antebi

Nat Commun. 2021; 12: 3486. Published online 2021 Jun 9. doi: 10.1038/s41467-021-23856-9

Correction in:: Nat Commun. 2021; 12: 5025.

PMCID:: PMC8190293

Abstract Article PDF–1007K

Select item 79951767.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 78843858.

High-throughput behavioral screen in C. elegans reveals Parkinson’s disease drug candidates

Salman Sohrabi, Danielle E. Mor, Rachel Kaletsky, William Keyes, Coleen T. Murphy

Commun Biol. 2021; 4: 203. Published online 2021 Feb 15. doi: 10.1038/s42003-021-01731-z

PMCID:: PMC7884385

Abstract Article PDF–2.1M

Select item 75850149.

Metformin rescues Parkinson’s disease phenotypes caused by hyperactive mitochondria

Danielle E. Mor, Salman Sohrabi, Rachel Kaletsky, William Keyes, Alp Tartici, Vrinda Kalia, Gary W. Miller, Coleen T. Murphy

Proc Natl Acad Sci U S A. 2020 Oct 20; 117(42): 26438–26447. Published online 2020 Oct 6. doi: 10.1073/pnas.2009838117

PMCID:: PMC7585014

Abstract Article PDF–5.0M

Select item 702117710.

An integrative tissue-network approach to identify and test human disease genes

Victoria Yao, Rachel Kaletsky, William Keyes, Danielle E Mor, Aaron K Wong, Salman Sohrabi, Coleen T Murphy, Olga G Troyanskaya

Nat Biotechnol. Author manuscript; available in PMC 2020 Apr 22.

Published before final editing as: Nat Biotechnol. 2018 Oct 22 : 10.1038/nbt.4246. doi: 10.1038/nbt.4246 [Epub ahead of print]

PMCID:: PMC7021177

Abstract Article PDF–1.8M

Select item 621659011.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 494261212.

The RNA-binding protein repertoire of Arabidopsis thaliana

Claudius Marondedze, Ludivine Thomas, Natalia L. Serrano, Kathryn S. Lilley, Chris Gehring

Sci Rep. 2016; 6: 29766. Published online 2016 Jul 11. doi: 10.1038/srep29766

PMCID:: PMC4942612

Abstract Article PDF–1.2M

Select item 468667213.

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing

Johannes Mansfeld, Nadine Urban, Steffen Priebe, Marco Groth, Christiane Frahm, Nils Hartmann, Juliane Gebauer, Meenakshi Ravichandran, Anne Dommaschk, Sebastian Schmeisser, Doreen Kuhlow, Shamci Monajembashi, Sibylle Bremer-Streck, Peter Hemmerich, Michael Kiehntopf, Nicola Zamboni, Christoph Englert, Reinhard Guthke, Christoph Kaleta, Matthias Platzer, Jürgen Sühnel, Otto W. Witte, Kim Zarse, Michael Ristow

Nat Commun. 2015; 6: 10043. Published online 2015 Dec 1. doi: 10.1038/ncomms10043