PMC Links for GEO Profiles (Select 99440862) - PMC

Select item 108105621.

Aging disrupts spatiotemporal regulation of germline stem cells and niche integrity

Michelle A. Urman, Nimmy S. John, Tyler Jung, ChangHwan Lee

Biol Open. 2024 Jan 15; 13(1): bio060261. Published online 2024 Jan 15. doi: 10.1242/bio.060261

PMCID:: PMC10810562

Select item 105925062.

Single-nucleus resolution mapping of the adult C. elegans and its application to elucidate inter- and trans-generational response to alcohol

Lisa Truong, Yen-Wei Chen, Rio Barrere-Cain, Max T. Levenson, Karissa Shuck, Wen Xiao, Eduardo da Veiga Beltrame, Blake Panter, Ella Reich, Paul W. Sternberg, Xia Yang, Patrick Allard

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112535. Published online 2023 May 23. doi: 10.1016/j.celrep.2023.112535

PMCID:: PMC10592506

Article PDF–2.5M

Select item 105235843.

LST-1 is a bifunctional regulator that feeds back on Notch-dependent transcription to regulate C. elegans germline stem cells

Ahlan S. Ferdous, Tina R. Lynch, Stephany J. Costa Dos Santos, Deep H. Kapadia, Sarah L. Crittenden, Judith Kimble

Proc Natl Acad Sci U S A. 2023 Sep 26; 120(39): e2309964120. Published online 2023 Sep 20. doi: 10.1073/pnas.2309964120

PMCID:: PMC10523584

Article PDF–1.7M

Select item 102596594.

The in vivo functional significance of PUF hub partnerships in C. elegans germline stem cells

Ahlan S. Ferdous, Stephany J. Costa Dos Santos, Charlotte R. Kanzler, Heaji Shin, Brian H. Carrick, Sarah L. Crittenden, Marvin Wickens, Judith Kimble

Development. 2023 May 1; 150(9): dev201705. Published online 2023 May 9. doi: 10.1242/dev.201705

PMCID:: PMC10259659

Article

Select item 99220295.

TRIM-NHL protein, NHL-2, modulates cell fate choices in the C. elegans germ line

John L. Brenner, Erin M. Jyo, Ariz Mohammad, Paul Fox, Vovanti Jones, Elaine Mardis, Tim Schedl, Eleanor M. Maine

Dev Biol. Author manuscript; available in PMC 2023 Feb 11.

Published in final edited form as: Dev Biol. 2022 Nov; 491: 43–55. Published online 2022 Sep 3. doi: 10.1016/j.ydbio.2022.08.010

PMCID:: PMC9922029

Article PDF–2.5M

Select item 92102876.

A sensitized genetic screen to identify regulators of Caenorhabditis elegans germline stem cells

Sarah Robinson-Thiewes, Aaron M Kershner, Heaji Shin, Kimberly A Haupt, Peggy Kroll-Connor, Judith Kimble

G3 (Bethesda) 2022 Mar; 12(3): jkab439. Published online 2021 Dec 23. doi: 10.1093/g3journal/jkab439

PMCID:: PMC9210287

Article PDF–1.3M

Select item 90584967.

Notch-dependent DNA cis-regulatory elements and their dose-dependent control of C. elegans stem cell self-renewal

Tina R. Lynch, Mingyu Xue, Cazza W. Czerniak, ChangHwan Lee, Judith Kimble

Development. 2022 Apr 1; 149(7): dev200332. Published online 2022 Apr 8. doi: 10.1242/dev.200332

PMCID:: PMC9058496

Article

Select item 88493378.

Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry

Antoine Baudrimont, Dimitra Paouneskou, Ariz Mohammad, Raffael Lichtenberger, Joshua Blundon, Yumi Kim, Markus Hartl, Sebastian Falk, Tim Schedl, Verena Jantsch

Sci Adv. 2022 Feb; 8(7): eabl8861. Published online 2022 Feb 16. doi: 10.1126/sciadv.abl8861

PMCID:: PMC8849337

Article PDF–7.2M

Select item 74677309.

Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche

Kacy L Gordon, Jay W Zussman, Xin Li, Camille Miller, David R Sherwood

eLife. 2020; 9: e56383. Published online 2020 Jul 21. doi: 10.7554/eLife.56383

PMCID:: PMC7467730

Article PDF–11M

Select item 715390110.

GLP-1 Notch—LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1

Jian Chen, Ariz Mohammad, Nanette Pazdernik, Huiyan Huang, Beth Bowman, Eric Tycksen, Tim Schedl

PLoS Genet. 2020 Mar; 16(3): e1008650. Published online 2020 Mar 20. doi: 10.1371/journal.pgen.1008650

PMCID:: PMC7153901

Article PDF–3.2M

Select item 704402511.

Niche cell wrapping ensures primordial germ cell quiescence and protection from intercellular cannibalism

Daniel C. McIntyre, Jeremy Nance

Curr Biol. Author manuscript; available in PMC 2021 Feb 24.

Published in final edited form as: Curr Biol. 2020 Feb 24; 30(4): 708–714.e4. Published online 2020 Jan 30. doi: 10.1016/j.cub.2019.12.021

PMCID:: PMC7044025

Article PDF–941K

Select item 672775312.

Sexual dimorphism of niche architecture and regulation of the Caenorhabditis elegans germline stem cell pool

Sarah L. Crittenden, ChangHwan Lee, Ipsita Mohanty, Sindhu Battula, Karla Knobel, Judith Kimble

Mol Biol Cell. 2019 Jul 1; 30(14): 1757–1769. doi: 10.1091/mbc.E19-03-0164

PMCID:: PMC6727753

Article PDF–5.9M

Select item 672471513.

Dynamics of Notch-Dependent Transcriptional Bursting in Its Native Context

ChangHwan Lee, Heaji Shin, Judith Kimble

Dev Cell. Author manuscript; available in PMC 2020 Aug 19.

Published in final edited form as: Dev Cell. 2019 Aug 19; 50(4): 426–435.e4. Published online 2019 Aug 1. doi: 10.1016/j.devcel.2019.07.001

PMCID:: PMC6724715

Article PDF–1.6M

Select item 650398314.

Rapid population-wide declines in stem cell number and activity during reproductive aging in C. elegans

Zuzana Kocsisova, Kerry Kornfeld, Tim Schedl

Development. 2019 Apr 15; 146(8): dev173195. Published online 2019 Apr 23. doi: 10.1242/dev.173195

PMCID:: PMC6503983

Article

Select item 574126715.

SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans

Heaji Shin, Kimberly A. Haupt, Aaron M. Kershner, Peggy Kroll-Conner, Marvin Wickens, Judith Kimble

PLoS Genet. 2017 Dec; 13(12): e1007121. Published online 2017 Dec 12. doi: 10.1371/journal.pgen.1007121

PMCID:: PMC5741267

Article PDF–7.1M

Select item 478811116.

Germline Stem Cell Differentiation Entails Regional Control of Cell Fate Regulator GLD-1 in Caenorhabditis elegans

John L. Brenner, Tim Schedl

Genetics. 2016 Mar; 202(3): 1085–1103. Published online 2016 Jan 11. doi: 10.1534/genetics.115.185678

PMCID:: PMC4788111

Article PDF–3.8M

Select item 395620217.

Discovery of two GLP-1/Notch target genes that account for the role of GLP-1/Notch signaling in stem cell maintenance

Aaron M. Kershner, Heaji Shin, Tyler J. Hansen, Judith Kimble

Proc Natl Acad Sci U S A. 2014 Mar 11; 111(10): 3739–3744. Published online 2014 Feb 24. doi: 10.1073/pnas.1401861111

PMCID:: PMC3956202

Article PDF–1.1M

Select item 305792318.

Empirically-controlled mapping of the Caenorhabditis elegans protein-protein interactome network

Nicolas Simonis, Jean-François Rual, Anne-Ruxandra Carvunis, Murat Tasan, Irma Lemmens, Tomoko Hirozane-Kishikawa, Tong Hao, Julie M Sahalie, Kavitha Venkatesan, Fana Gebreab, Sebiha Cevik, Niels Klitgord, Changyu Fan, Pascal Braun, Ning Li, Nono Ayivi-Guedehoussou, Elizabeth Dann, Nicolas Bertin, David Szeto, Amélie Dricot, Muhammed A Yildirim, Chenwei Lin, Anne-Sophie de Smet, Huey-Ling Kao, Christophe Simon, Alex Smolyar, Jin Sook Ahn, Muneesh Tewari, Mike Boxem, Stuart Milstein, Haiyuan Yu, Matija Dreze, Jean Vandenhaute, Kristin C Gunsalus, Michael E Cusick, David E Hill, Jan Tavernier, Frederick P Roth, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2011 Mar 15.

Published in final edited form as: Nat Methods. 2009 Jan; 6(1): 47–54. doi: 10.1038/nmeth.1279

PMCID:: PMC3057923

Article PDF–3.0M

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