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Select item 95700271.

Axenic Culture of Caenorhabditis elegans Alters Lysosomal/Proteasomal Balance and Increases Neuropeptide Expression

Huaihan Cai, Ping Wu, Lieselot Vandemeulebroucke, Ineke Dhondt, Madina Rasulova, Andy Vierstraete, Bart P. Braeckman

Int J Mol Sci. 2022 Oct; 23(19): 11517. Published online 2022 Sep 29. doi: 10.3390/ijms231911517

PMCID:: PMC9570027

Abstract Article PDF–6.2M

Select item 93884632.

Identification of healthspan-promoting genes in Caenorhabditis elegans based on a human GWAS study

Nadine Saul, Ineke Dhondt, Mikko Kuokkanen, Markus Perola, Clara Verschuuren, Brecht Wouters, Henrik von Chrzanowski, Winnok H. De Vos, Liesbet Temmerman, Walter Luyten, Aleksandra Zečić, Tim Loier, Christian Schmitz-Linneweber, Bart P. Braeckman

Biogerontology. 2022; 23(4): 431–452. Published online 2022 Jun 24. doi: 10.1007/s10522-022-09969-8

PMCID:: PMC9388463

Abstract Article PDF–2.1M

Select item 62225663.

Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamine Aggregation

Theodore W. Peters, Christopher S. Nelson, Akos A. Gerencser, Kathleen J. Dumas, Brandon Tavshanjian, Kyu Chul Chang, Gordon J. Lithgow, Robert E. Hughes

G3 (Bethesda) 2018 Nov; 8(11): 3421–3431. Published online 2018 Sep 11. doi: 10.1534/g3.118.200289

PMCID:: PMC6222566

Abstract Article PDF–1.8M

Select item 62165904.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 50219795.

Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!

Siegfried Hekimi, Ying Wang, Alycia Noë

Front Genet. 2016; 7: 161. Published online 2016 Sep 14. doi: 10.3389/fgene.2016.00161

PMCID:: PMC5021979

Abstract Article PDF–960K

Select item 47815976.

Ubiquitin-mediated pathways in C. elegans.

Edward T Kipreos

WormBook. 2005 : 1–24. Published online 2005 Dec 1. doi: 10.1895/wormbook.1.36.1

PMCID:: PMC4781597

Abstract Article

Select item 47675597.

A combined binary interaction and phenotypic map of C. elegans cell polarity proteins

Thijs Koorman, Diana Klompstra, Monique van der Voet, Irma Lemmens, João J. Ramalho, Susan Nieuwenhuize, Sander van den Heuvel, Jan Tavernier, Jeremy Nance, Mike Boxem

Nat Cell Biol. Author manuscript; available in PMC 2016 Jul 18.

Published in final edited form as: Nat Cell Biol. 2016 Mar; 18(3): 337–346. Published online 2016 Jan 18. doi: 10.1038/ncb3300

PMCID:: PMC4767559

Abstract Article PDF–1.7M

Select item 46141078.

Fitting WWP-1 in the dietary restriction network

Andrea C Carrano, Tony Hunter

Cell Cycle. 2015 May 15; 14(10): 1485–1486. Published online 2015 May 5. doi: 10.1080/15384101.2015.1032642

PMCID:: PMC4614107

Article PDF–112K

Select item 45739029.

The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo

Zhuo Du, Anthony Santella, Fei He, Pavak K. Shah, Yuko Kamikawa, Zhirong Bao

Dev Cell. Author manuscript; available in PMC 2016 Sep 14.

Published in final edited form as: Dev Cell. 2015 Sep 14; 34(5): 592–607. Published online 2015 Aug 27. doi: 10.1016/j.devcel.2015.07.014

PMCID:: PMC4573902

Abstract Article PDF–2.6M

Select item 434636810.

A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans

Andrea C. Carrano, Andrew Dillin, Tony Hunter

Nat Commun. Author manuscript; available in PMC 2015 Mar 2.

Published in final edited form as: Nat Commun. 2014; 5: 3772. Published online 2014 May 8. doi: 10.1038/ncomms4772

PMCID:: PMC4346368

Abstract Article PDF–399K

Select item 367988911.

Dissection of the Mammalian Midbody Proteome Reveals Conserved Cytokinesis Mechanisms

Ahna R. Skop, Hongbin Liu, John Yates, III, Barbara J. Meyer, Rebecca Heald

Science. Author manuscript; available in PMC 2013 Jun 12.

Published in final edited form as: Science. 2004 Jul 2; 305(5680): 61–66. Published online 2004 May 27. doi: 10.1126/science.1097931

PMCID:: PMC3679889

Abstract Article PDF–1.5M

Select item 365827712.

SH3 interactome conserves general function over specific form

Xiaofeng Xin, David Gfeller, Jackie Cheng, Raffi Tonikian, Lin Sun, Ailan Guo, Lianet Lopez, Alevtina Pavlenco, Adenrele Akintobi, Yingnan Zhang, Jean-François Rual, Bridget Currell, Somasekar Seshagiri, Tong Hao, Xinping Yang, Yun A Shen, Kourosh Salehi-Ashtiani, Jingjing Li, Aaron T Cheng, Dryden Bouamalay, Adrien Lugari, David E Hill, Mark L Grimes, David G Drubin, Barth D Grant, Marc Vidal, Charles Boone, Sachdev S Sidhu, Gary D Bader

Mol Syst Biol. 2013; 9: 652. Published online 2013 Apr 2. doi: 10.1038/msb.2013.9

PMCID:: PMC3658277

Abstract Article PDF–2.3M

Select item 310207713.

OrthoList: A Compendium of C. elegans Genes with Human Orthologs

Daniel D. Shaye, Iva Greenwald

PLoS One. 2011; 6(5): e20085. Published online 2011 May 25. doi: 10.1371/journal.pone.0020085

Correction in:: PLoS One. 2014; 9(1): 10.1371/annotation/f5ffb738-a176-4a43-b0e0-249cdea45fe0.

PMCID:: PMC3102077

Abstract Article PDF–530K

Select item 305792314.

Empirically-controlled mapping of the Caenorhabditis elegans protein-protein interactome network

Nicolas Simonis, Jean-François Rual, Anne-Ruxandra Carvunis, Murat Tasan, Irma Lemmens, Tomoko Hirozane-Kishikawa, Tong Hao, Julie M Sahalie, Kavitha Venkatesan, Fana Gebreab, Sebiha Cevik, Niels Klitgord, Changyu Fan, Pascal Braun, Ning Li, Nono Ayivi-Guedehoussou, Elizabeth Dann, Nicolas Bertin, David Szeto, Amélie Dricot, Muhammed A Yildirim, Chenwei Lin, Anne-Sophie de Smet, Huey-Ling Kao, Christophe Simon, Alex Smolyar, Jin Sook Ahn, Muneesh Tewari, Mike Boxem, Stuart Milstein, Haiyuan Yu, Matija Dreze, Jean Vandenhaute, Kristin C Gunsalus, Michael E Cusick, David E Hill, Jan Tavernier, Frederick P Roth, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2011 Mar 15.

Published in final edited form as: Nat Methods. 2009 Jan; 6(1): 47–54. doi: 10.1038/nmeth.1279

PMCID:: PMC3057923

Abstract Article PDF–3.0M

Select item 283048315.

WWP-1 Is a Novel Modulator of the DAF-2 Insulin-Like Signaling Network Involved in Pore-Forming Toxin Cellular Defenses in Caenorhabditis elegans

Chang-Shi Chen, Audrey Bellier, Cheng-Yuan Kao, Ya-Luen Yang, Huan-Da Chen, Ferdinand C. O. Los, Raffi V. Aroian

PLoS One. 2010; 5(3): e9494. Published online 2010 Mar 2. doi: 10.1371/journal.pone.0009494

PMCID:: PMC2830483

Abstract Article PDF–782K

Select item 281573216.

Ubiquitin ligases join the field of dietary restriction in C.elegans

Mark Lucanic, Pankaj Kapahi

Aging (Albany NY) 2009 Sep; 1(9): 751–752. Published online 2009 Sep 3. doi: 10.18632/aging.100084

PMCID:: PMC2815732

Article PDF–140K

Select item 274674817.

A conserved ubiquitination pathway determines longevity in response to diet restriction

Andrea C. Carrano, Zheng Liu, Andrew Dillin, Tony Hunter

Nature. Author manuscript; available in PMC 2010 Jan 16.

Published in final edited form as: Nature. 2009 Jul 16; 460(7253): 396–399. Published online 2009 Jun 24. doi: 10.1038/nature08130

PMCID:: PMC2746748

Abstract Article PDF–988K

Select item 259647818.

A protein domain-based interactome network for C. elegans early embryogenesis

Mike Boxem, Zoltan Maliga, Niels Klitgord, Na Li, Irma Lemmens, Miyeko Mana, Lorenzo de Lichtervelde, Joram D. Mul, Diederik van de Peut, Maxime Devos, Nicolas Simonis, Muhammed A. Yildirim, Murat Cokol, Huey-Ling Kao, Anne-Sophie de Smet, Haidong Wang, Anne-Lore Schlaitz, Tong Hao, Stuart Milstein, Changyu Fan, Mike Tipsword, Kevin Drew, Matilde Galli, Kahn Rhrissorrakrai, David Drechsel, Daphne Koller, Frederick P. Roth, Lilia M. Iakoucheva, A. Keith Dunker, Richard Bonneau, Kristin C. Gunsalus, David E. Hill, Fabio Piano, Jan Tavernier, Sander van den Heuvel, Anthony A. Hyman, Marc Vidal

Cell. Author manuscript; available in PMC 2009 Aug 8.

Published in final edited form as: Cell. 2008 Aug 8; 134(3): 534–545. doi: 10.1016/j.cell.2008.07.009

Correction in:: volume 151 on page 1633

PMCID:: PMC2596478

Abstract Article PDF–4.0M

Select item 258294919.

Profiling Synaptic Proteins Identifies Regulators of Insulin Secretion and Lifespan

QueeLim Ch'ng, Derek Sieburth, Joshua M. Kaplan

PLoS Genet. 2008 Nov; 4(11): e1000283. Published online 2008 Nov 28. doi: 10.1371/journal.pgen.1000283

PMCID:: PMC2582949

Abstract Article PDF–801K

Select item 204919820.

Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants

Andrew V. Samuelson, Christopher E. Carr, Gary Ruvkun

Genes Dev. 2007 Nov 15; 21(22): 2976–2994. doi: 10.1101/gad.1588907

PMCID:: PMC2049198

Abstract Article PDF–832K

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