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Select item 106358331.

A MEC-2/stomatin condensate liquid-to-solid phase transition controls neuronal mechanotransduction during touch sensing

Neus Sanfeliu-Cerdán, Frederic Català-Castro, Borja Mateos, Carla Garcia-Cabau, Maria Ribera, Iris Ruider, Montserrat Porta-de-la-Riva, Adrià Canals-Calderón, Stefan Wieser, Xavier Salvatella, Michael Krieg

Nat Cell Biol. 2023; 25(11): 1590–1599. Published online 2023 Oct 19. doi: 10.1038/s41556-023-01247-0

PMCID:: PMC10635833

Abstract Article PDF–11M

Select item 100357672.

A Conserved Role for Stomatin Domain Genes in Olfactory Behavior

Xiaoyu Liang, Morgan Taylor, Rebekah Napier-Jameson, Canyon Calovich-Benne, Adam Norris

eNeuro. 2023 Mar; 10(3): ENEURO.0457-22.2023. Prepublished online 2023 Mar 1. Published online 2023 Mar 21. doi: 10.1523/ENEURO.0457-22.2023

PMCID:: PMC10035767

Abstract Article PDF–1.8M

Select item 96356623.

Genetic screens identified dual roles of microtubule-associated serine threonine kinase and CREB within a single thermosensory neuron in the regulation of Caenorhabditis elegans thermotaxis behavior

Shunji Nakano, Airi Nakayama, Hiroo Kuroyanagi, Riku Yamashiro, Yuki Tsukada, Ikue Mori

G3 (Bethesda) 2022 Nov; 12(11): jkac248. Published online 2022 Sep 14. doi: 10.1093/g3journal/jkac248

PMCID:: PMC9635662

Abstract Article PDF–2.3M

Select item 89346394.

Sensory neuron transcriptomes reveal complex neuron-specific function and regulation of mec-2/Stomatin splicing

Xiaoyu Liang, Canyon Calovich-Benne, Adam Norris

Nucleic Acids Res. 2022 Mar 21; 50(5): 2401–2416. Published online 2021 Dec 8. doi: 10.1093/nar/gkab1134

PMCID:: PMC8934639

Abstract Article PDF–6.1M

Select item 79339855.

DEG/ENaC/ASIC channels vary in their sensitivity to anti-hypertensive and non-steroidal anti-inflammatory drugs

Sylvia Fechner, Isabel D’Alessandro, Lingxin Wang, Calvin Tower, Li Tao, Miriam B. Goodman

J Gen Physiol. 2021 Apr 5; 153(4): e202012655. Published online 2021 Mar 3. doi: 10.1085/jgp.202012655

PMCID:: PMC7933985

Abstract Article PDF–3.9M

Select item 67825806.

Distinct Signaling Pathways Mediate Touch and Osmosensory Responses in a Polymodal Sensory Neuron

Anne C. Hart, Jamie Kass, Jonathan E. Shapiro, Joshua M. Kaplan

J Neurosci. 1999 Mar 15; 19(6): 1952–1958. doi: 10.1523/JNEUROSCI.19-06-01952.1999

PMCID:: PMC6782580

Abstract Article PDF–187K

Select item 66735307.

Nanoscale Organization of the MEC-4 DEG/ENaC Sensory Mechanotransduction Channel in Caenorhabditis elegans Touch Receptor Neurons

Juan G. Cueva, Atticus Mulholland, Miriam B. Goodman

J Neurosci. 2007 Dec 19; 27(51): 14089–14098. doi: 10.1523/JNEUROSCI.4179-07.2007

PMCID:: PMC6673530

Abstract Article PDF–691K

Select item 62165908.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 56121229.

Regulation of the epithelial Na⁺ channel by paraoxonase-2

Shujie Shi, Teresa M. Buck, Carol L. Kinlough, Allison L. Marciszyn, Rebecca P. Hughey, Martin Chalfie, Jeffrey L. Brodsky, Thomas R. Kleyman

J Biol Chem. 2017 Sep 22; 292(38): 15927–15938. Published online 2017 Aug 2. doi: 10.1074/jbc.M117.785253

PMCID:: PMC5612122

Abstract Article PDF–2.1M

Select item 483188110.

Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins

Yushu Chen, Shashank Bharill, Zeynep Altun, Robert O’Hagan, Brian Coblitz, Ehud Y. Isacoff, Martin Chalfie

Mol Biol Cell. 2016 Apr 15; 27(8): 1272–1285. doi: 10.1091/mbc.E15-08-0561

PMCID:: PMC4831881

Abstract Article PDF–3.8M

Select item 478790311.

The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes

Markus M. Rinschen, Puneet Bharill, Xiongwu Wu, Priyanka Kohli, Matthäus J. Reinert, Oliver Kretz, Isabel Saez, Bernhard Schermer, Martin Höhne, Malte P. Bartram, Sriram Aravamudhan, Bernard R. Brooks, David Vilchez, Tobias B. Huber, Roman-Ulrich Müller, Marcus Krüger, Thomas Benzing

Hum Mol Genet. 2016 Apr 1; 25(7): 1328–1344. Published online 2016 Jan 19. doi: 10.1093/hmg/ddw016

PMCID:: PMC4787903

Abstract Article PDF–1.0M

Select item 478103212.

Culture of embryonic C. elegans cells for electrophysiological and pharmacological analyses.

Laura Bianchi, Monica Driscoll

WormBook. 2006 : 1–15. Published online 2006 Sep 30. doi: 10.1895/wormbook.1.122.1

PMCID:: PMC4781032

Abstract Article

Select item 478102413.

Heterologous expression of C. elegans ion channels in Xenopus oocytes.

Laura Bianchi, Monica Driscoll

WormBook. 2006 : 1–16. Published online 2006 Aug 1. doi: 10.1895/wormbook.1.117.1

PMCID:: PMC4781024

Abstract Article

Select item 457720614.

Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans

Yushu Chen, Shashank Bharill, Ehud Y. Isacoff, Martin Chalfie

Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37): 11690–11695. Published online 2015 Aug 31. doi: 10.1073/pnas.1515968112

PMCID:: PMC4577206

Abstract Article PDF–1.2M

Select item 403626415.

A Disease-causing Mutation Illuminates the Protein Membrane Topology of the Kidney-expressed Prohibitin Homology (PHB) Domain Protein Podocin

Eva-Maria Schurek, Linus A. Völker, Judit Tax, Tobias Lamkemeyer, Markus M. Rinschen, Denise Ungrue, John E. Kratz, III, Lalida Sirianant, Karl Kunzelmann, Martin Chalfie, Bernhard Schermer, Thomas Benzing, Martin Höhne

J Biol Chem. 2014 Apr 18; 289(16): 11262–11271. Published online 2014 Mar 4. doi: 10.1074/jbc.M113.521773