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Select item 99920951.

A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes

Gholamreza Fazeli, Roni Levin-Konigsberg, Michael C. Bassik, Christian Stigloher, Ann M. Wehman

Curr Biol. Author manuscript; available in PMC 2024 Feb 27.

Published in final edited form as: Curr Biol. 2023 Feb 27; 33(4): 607–621.e7. Published online 2023 Jan 17. doi: 10.1016/j.cub.2022.12.041

PMCID:: PMC9992095

Abstract Article PDF–2.5M

Select item 98854402.

Intracellular lipid surveillance by small G protein geranylgeranylation

Abigail Watterson, Lexus Tatge, Naureen Wajahat, Sonja L. B. Arneaud, Rene Solano Fonseca, Shaghayegh T. Beheshti, Patrick Metang, Melina Mihelakis, Kielen R. Zuurbier, Chase D. Corley, Ishmael Dehghan, Jeffrey G. McDonald, Peter M. Douglas

Nature. Author manuscript; available in PMC 2023 Jan 30.

Published in final edited form as: Nature. 2022 May; 605(7911): 736–740. Published online 2022 May 18. doi: 10.1038/s41586-022-04729-7

PMCID:: PMC9885440

Abstract Article PDF–4.2M

Select item 90361183.

The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy

Aileen K. Sewell, Zachary C. Poss, Christopher C. Ebmeier, Jeremy R. Jacobsen, William M. Old, Min Han

iScience. 2022 May 20; 25(5): 104186. Published online 2022 Mar 31. doi: 10.1016/j.isci.2022.104186

PMCID:: PMC9036118

Abstract Article PDF–2.4M

Select item 89537234.

Anabolic Function Downstream of TOR Controls Trade-offs Between Longevity and Reproduction at the Level of Specific Tissues in C. elegans

Amber C. Howard, Dilawar Mir, Santina Snow, Jordan Horrocks, Hussein Sayed, Zhengxin Ma, Aric N. Rogers

Front Aging. 2021; 2: 725068. Published online 2021 Sep 10. doi: 10.3389/fragi.2021.725068

PMCID:: PMC8953723

Abstract Article PDF–2.1M

Select item 88572265.

ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1

Cyril Statzer, Jin Meng, Richard Venz, Monet Bland, Stacey Robida-Stubbs, Krina Patel, Dunja Petrovic, Raffaella Emsley, Pengpeng Liu, Ianessa Morantte, Cole Haynes, William B. Mair, Alban Longchamp, Milos R. Filipovic, T. Keith Blackwell, Collin Y. Ewald

Nat Commun. 2022; 13: 967. Published online 2022 Feb 18. doi: 10.1038/s41467-022-28599-9

PMCID:: PMC8857226

Abstract Article PDF–2.5M

Select item 85207136.

Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration

Kerry C. Ryan, Zahra Ashkavand, Shaarika Sarasija, Jocelyn T. Laboy, Rohan Samarakoon, Kenneth R. Norman

Aging Cell. 2021 Oct; 20(10): e13472. Published online 2021 Sep 9. doi: 10.1111/acel.13472

PMCID:: PMC8520713

Abstract Article PDF–1.6M

Select item 84425757.

Insulin/IGF-1 signaling and heat stress differentially regulate HSF1 activities in germline development

Stacey L. Edwards, Purevsuren Erdenebat, Allison C. Morphis, Lalit Kumar, Lai Wang, Tomasz Chamera, Constantin Georgescu, Jonathan D. Wren, Jian Li

Cell Rep. Author manuscript; available in PMC 2021 Sep 15.

Published in final edited form as: Cell Rep. 2021 Aug 31; 36(9): 109623. doi: 10.1016/j.celrep.2021.109623

PMCID:: PMC8442575

Abstract Article PDF–1.5M

Select item 62165908.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 58198329.

Rictor/TORC2 mediates gut-to-brain signaling in the regulation of phenotypic plasticity in C. elegans

Michael P. O’Donnell, Pin-Hao Chao, Jan E. Kammenga, Piali Sengupta

PLoS Genet. 2018 Feb; 14(2): e1007213. Published online 2018 Feb 7. doi: 10.1371/journal.pgen.1007213

PMCID:: PMC5819832

Abstract Article PDF–11M

Select item 544463210.

The intestinal TORC2 signaling pathway contributes to associative learning in Caenorhabditis elegans

Naoko Sakai, Hayao Ohno, Masahiro Tomioka, Yuichi Iino

PLoS One. 2017; 12(5): e0177900. Published online 2017 May 25. doi: 10.1371/journal.pone.0177900

PMCID:: PMC5444632

Abstract Article PDF–2.8M

Select item 476915211.

Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span

Sandeep Kumar, Nicholas Dietrich, Kerry Kornfeld

PLoS Genet. 2016 Feb; 12(2): e1005866. Published online 2016 Feb 26. doi: 10.1371/journal.pgen.1005866

PMCID:: PMC4769152

Abstract Article PDF–5.0M

Select item 418043712.

Prohibitin-Mediated Lifespan and Mitochondrial Stress Implicate SGK-1, Insulin/IGF and mTORC2 in C. elegans

Roxani Gatsi, Bettina Schulze, María Jesús Rodríguez-Palero, Blanca Hernando-Rodríguez, Ralf Baumeister, Marta Artal-Sanz

PLoS One. 2014; 9(9): e107671. Published online 2014 Sep 29. doi: 10.1371/journal.pone.0107671

PMCID:: PMC4180437

Abstract Article PDF–1.4M

Select item 417265613.

mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity

Masaki Mizunuma, Elke Neumann-Haefelin, Natalie Moroz, Yujie Li, T Keith Blackwell

Aging Cell. 2014 Oct; 13(5): 869–878. Published online 2014 Jul 9. doi: 10.1111/acel.12248

PMCID:: PMC4172656

Abstract Article PDF–390K

Select item 387777114.

TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development

Vanessa Ruf, Christina Holzem, Tobias Peyman, Gerd Walz, T. Keith Blackwell, Elke Neumann-Haefelin

Dev Biol. Author manuscript; available in PMC 2014 Dec 15.

Published in final edited form as: Dev Biol. 2013 Dec 15; 384(2): 10.1016/j.ydbio.2013.08.011. Published online 2013 Aug 20. doi: 10.1016/j.ydbio.2013.08.011