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Select item 107611211.

CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing

Doreen I. Lugano, Lindsey N. Barrett, Dale Chaput, Margaret A. Park, Sandy D. Westerheide

RNA Biol. 2024; 21(1): 1–11. Published online 2023 Dec 21. doi: 10.1080/15476286.2023.2289707

PMCID:: PMC10761121

Abstract Article PDF–2.5M

Select item 102877382.

Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response

Eunah Kim, Andrea Annibal, Yujin Lee, Hae-Eun H. Park, Seokjin Ham, Dae-Eun Jeong, Younghun Kim, Sangsoon Park, Sujeong Kwon, Yoonji Jung, JiSoo Park, Sieun S. Kim, Adam Antebi, Seung-Jae V. Lee

Nat Commun. 2023; 14: 3716. Published online 2023 Jun 22. doi: 10.1038/s41467-023-39393-6

PMCID:: PMC10287738

Abstract Article PDF–1.7M

Select item 98941173.

The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways

Kai Mao, Peter Breen, Gary Ruvkun

Proc Natl Acad Sci U S A. 2022 Dec 6; 119(49): e2215966119. Published online 2022 Nov 29. doi: 10.1073/pnas.2215966119

PMCID:: PMC9894117

Abstract Article PDF–3.5M

Select item 96427804.

Cobalt chloride has beneficial effects across species through a hormetic mechanism

Alfonso Schiavi, Alessandra Runci, Teresa Maiorino, Francesco Davide Naso, Marta Barenys, Ellen Fritsche, Flavie Strappazzon, Natascia Ventura

Front Cell Dev Biol. 2022; 10: 986835. Published online 2022 Oct 25. doi: 10.3389/fcell.2022.986835

PMCID:: PMC9642780

Abstract Article PDF–1.7M

Select item 95481815.

Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents

Alan D. Winter, Elissa Tjahjono, Leonardo J. Beltrán, Iain L. Johnstone, Neil J. Bulleid, Antony P. Page

BMC Biol. 2022; 20: 228. Published online 2022 Oct 8. doi: 10.1186/s12915-022-01415-y

PMCID:: PMC9548181

Abstract Article PDF–2.5M

Select item 94378486.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 90985007.

Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans

Silvia Maglioni, Alfonso Schiavi, Marlen Melcher, Vanessa Brinkmann, Zhongrui Luo, Anna Laromaine, Nuno Raimundo, Joel N. Meyer, Felix Distelmaier, Natascia Ventura

Nat Commun. 2022; 13: 2620. Published online 2022 May 12. doi: 10.1038/s41467-022-29972-4

PMCID:: PMC9098500

Abstract Article PDF–2.2M

Select item 90903268.

Dithiothreitol causes toxicity in C. elegans by modulating the methionine–homocysteine cycle

Gokul G, Jogender Singh

eLife. 2022; 11: e76021. Published online 2022 Apr 19. doi: 10.7554/eLife.76021

PMCID:: PMC9090326

Abstract Article PDF–15M

Select item 90642979.

A tRNA processing enzyme is a key regulator of the mitochondrial unfolded protein response

James P Held, Gaomin Feng, Benjamin R Saunders, Claudia V Pereira, Kristopher Burkewitz, Maulik R Patel

eLife. 2022; 11: e71634. Published online 2022 Apr 22. doi: 10.7554/eLife.71634

PMCID:: PMC9064297

Abstract Article PDF–4.6M

Select item 902071610.

A modified TurboID approach identifies tissue-specific centriolar components in C. elegans

Elisabeth Holzer, Cornelia Rumpf-Kienzl, Sebastian Falk, Alexander Dammermann

PLoS Genet. 2022 Apr; 18(4): e1010150. Published online 2022 Apr 20. doi: 10.1371/journal.pgen.1010150

Correction in:: PLoS Genet. 2023 Feb; 19(2): e1010645.

PMCID:: PMC9020716

Abstract Article PDF–2.0M

Select item 882575411.

Bacterial peptidoglycan muropeptides benefit mitochondrial homeostasis and animal physiology by acting as ATP synthase agonists

Dong Tian, Min Han

Dev Cell. Author manuscript; available in PMC 2023 Feb 7.

Published in final edited form as: Dev Cell. 2022 Feb 7; 57(3): 361–372.e5. Published online 2022 Jan 18. doi: 10.1016/j.devcel.2021.12.016

PMCID:: PMC8825754

Abstract Article PDF–2.0M

Select item 881402612.

Mitochondrial protein import determines lifespan through metabolic reprogramming and de novo serine biosynthesis

Eirini Lionaki, Ilias Gkikas, Ioanna Daskalaki, Maria-Konstantina Ioannidi, Maria I. Klapa, Nektarios Tavernarakis

Nat Commun. 2022; 13: 651. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28272-1

PMCID:: PMC8814026

Abstract Article PDF–2.3M

Select item 879207413.

Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type C. elegans strains

Arwen W. Gao, Gaby El Alam, Amélia Lalou, Terytty Yang Li, Marte Molenaars, Yunyun Zhu, Katherine A. Overmyer, Evgenia Shishkova, Kevin Hof, Maroun Bou Sleiman, Riekelt H. Houtkooper, Joshua J. Coon, Johan Auwerx

iScience. 2022 Feb 18; 25(2): 103734. Published online 2022 Jan 5. doi: 10.1016/j.isci.2022.103734

PMCID:: PMC8792074

Abstract Article PDF–4.6M

Select item 875005514.

High-Content C. elegans Screen Identifies Natural Compounds Impacting Mitochondria-Lipid Homeostasis and Promoting Healthspan

Silvia Maglioni, Nayna Arsalan, Anna Hamacher, Shiwa Afshar, Alfonso Schiavi, Mathias Beller, Natascia Ventura

Cells. 2022 Jan; 11(1): 100. Published online 2021 Dec 29. doi: 10.3390/cells11010100

PMCID:: PMC8750055

Abstract Article PDF–3.6M

Select item 852733315.

High confidence ATFS-1 target genes for quantifying activation of the mitochondrial unfolded protein response

Sonja K Soo, Jeremy M Van Raamsdonk

MicroPubl Biol. 2021; 2021: 10.17912/micropub.biology.000484. Published online 2021 Oct 19. doi: 10.17912/micropub.biology.000484

PMCID:: PMC8527333

Abstract Article PDF–2.1M

Select item 844679316.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 842868417.

Allele-specific mitochondrial stress induced by Multiple Mitochondrial Dysfunctions Syndrome 1 pathogenic mutations modeled in Caenorhabditis elegans

Peter A. Kropp, Jing Wu, Michael Reidy, Sanjay Shrestha, Kyle Rhodehouse, Philippa Rogers, Michael N. Sack, Andy Golden

PLoS Genet. 2021 Aug; 17(8): e1009771. Published online 2021 Aug 27. doi: 10.1371/journal.pgen.1009771

PMCID:: PMC8428684

Abstract Article PDF–3.2M

Select item 841007818.

The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging

Suzanne Angeli, Anna Foulger, Manish Chamoli, Tanuja Harshani Peiris, Akos Gerencser, Azar Asadi Shahmirzadi, Julie Andersen, Gordon Lithgow

eLife. 2021; 10: e63453. Published online 2021 Sep 1. doi: 10.7554/eLife.63453

PMCID:: PMC8410078

Abstract Article PDF–4.8M

Select item 840392219.

Genome-wide screen identifies curli amyloid fibril as a bacterial component promoting host neurodegeneration

Chenyin Wang, Chun Yin Lau, Fuqiang Ma, Chaogu Zheng

Proc Natl Acad Sci U S A. 2021 Aug 24; 118(34): e2106504118. Published online 2021 Aug 19. doi: 10.1073/pnas.2106504118

Correction in:: Proc Natl Acad Sci U S A. 2021 Oct 12; 118(41): e2116257118.

PMCID:: PMC8403922

Abstract Article PDF–2.5M

Select item 833118320.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833