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Select item 105652431.

PUF-8, a C. elegans ortholog of the RNA-binding proteins PUM1 and PUM2, is required for robustness of the cell death fate

Jimei Xu, Yanwen Jiang, Ryan Sherrard, Kyoko Ikegami, Barbara Conradt

Development. 2023 Oct 1; 150(19): dev201167. Published online 2023 Oct 6. doi: 10.1242/dev.201167

PMCID:: PMC10565243

Abstract Article

Select item 99771492.

Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements

Tatiana Maroilley, Stephane Flibotte, Francesca Jean, Victoria Rodrigues Alves Barbosa, Andrew Galbraith, Afiya Razia Chida, Filip Cotra, Xiao Li, Larisa Oncea, Mark Edgley, Don Moerman, Maja Tarailo-Graovac

Genome Res. 2023 Jan; 33(1): 154–167. doi: 10.1101/gr.276988.122

PMCID:: PMC9977149

Abstract Article PDF–8.7M

Select item 99227343.

Patient-specific variants of NFU1/NFU-1 disrupt cholinergic signaling in a model of multiple mitochondrial dysfunctions syndrome 1

Peter A. Kropp, Philippa Rogers, Sydney E. Kelly, Rebecca McWhirter, Willow D. Goff, Ian M. Levitan, David M. Miller, III, Andy Golden

Dis Model Mech. 2023 Feb 1; 16(2): dmm049594. Published online 2023 Feb 1. doi: 10.1242/dmm.049594

PMCID:: PMC9922734

Abstract Article

Select item 95693734.

Maintenance of neurotransmitter identity by Hox proteins through a homeostatic mechanism

Weidong Feng, Honorine Destain, Jayson J. Smith, Paschalis Kratsios

Nat Commun. 2022; 13: 6097. Published online 2022 Oct 15. doi: 10.1038/s41467-022-33781-0

PMCID:: PMC9569373

Abstract Article PDF–2.0M

Select item 90509225.

Robust regulatory architecture of pan-neuronal gene expression

Eduardo Leyva-Díaz, Oliver Hobert

Curr Biol. Author manuscript; available in PMC 2023 Apr 25.

Published in final edited form as: Curr Biol. 2022 Apr 25; 32(8): 1715–1727.e8. Published online 2022 Mar 7. doi: 10.1016/j.cub.2022.02.040

PMCID:: PMC9050922

Abstract Article PDF–2.4M

Select item 84492566.

Transgenic reporter analysis of ChIP-Seq-defined enhancers identifies novel target genes for the terminal selector UNC-3/Collier/Ebf

Yinan Li, Paschalis Kratsios

MicroPubl Biol. 2021; 2021: 10.17912/micropub.biology.000453. Published online 2021 Sep 14. doi: 10.17912/micropub.biology.000453

PMCID:: PMC8449256

Abstract Article PDF–2.0M

Select item 82253927.

The Prop1-like homeobox gene unc-42 specifies the identity of synaptically connected neurons

Emily G Berghoff, Lori Glenwinkel, Abhishek Bhattacharya, HaoSheng Sun, Erdem Varol, Nicki Mohammadi, Amelia Antone, Yi Feng, Ken Nguyen, Steven J Cook, Jordan F Wood, Neda Masoudi, Cyril C Cros, Yasmin H Ramadan, Denise M Ferkey, David H Hall, Oliver Hobert

eLife. 2021; 10: e64903. Published online 2021 Jun 24. doi: 10.7554/eLife.64903

PMCID:: PMC8225392

Abstract Article PDF–6.6M

Select item 79951768.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 77814849.

Expression pattern determines regulatory logic

Carlos Mora-Martinez

PLoS One. 2021; 16(1): e0244864. Published online 2021 Jan 4. doi: 10.1371/journal.pone.0244864

PMCID:: PMC7781484

Abstract Article PDF–4.0M

Select item 752946010.

Establishment and maintenance of motor neuron identity via temporal modularity in terminal selector function

Yinan Li, Anthony Osuma, Edgar Correa, Munachiso A Okebalama, Pauline Dao, Olivia Gaylord, Jihad Aburas, Priota Islam, André EX Brown, Paschalis Kratsios

eLife. 2020; 9: e59464. Published online 2020 Oct 1. doi: 10.7554/eLife.59464

PMCID:: PMC7529460

Abstract Article PDF–3.9M

Select item 694444511.

A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life

Weidong Feng, Yinan Li, Pauline Dao, Jihad Aburas, Priota Islam, Benayahu Elbaz, Anna Kolarzyk, André EX Brown, Paschalis Kratsios

eLife. 2020; 9: e50065. Published online 2020 Jan 3. doi: 10.7554/eLife.50065

PMCID:: PMC6944445

Abstract Article PDF–2.8M

Select item 638589212.

The multipotency-to-commitment transition (MCT) in C. elegans: implications for reprogramming from cells to organs

MR. Erik A. Spickard, Pradeep M. Joshi, Joel H. Rothman

FEBS Lett. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: FEBS Lett. 2018 Mar; 592(6): 838–851. Published online 2018 Feb 1. doi: 10.1002/1873-3468.12977

PMCID:: PMC6385892

Abstract Article PDF–646K

Select item 633939913.

An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development

Catarina Catela, Edgar Correa, Kailong Wen, Jihad Aburas, Laura Croci, G. Giacomo Consalez, Paschalis Kratsios

Neural Dev. 2019; 14: 2. Published online 2019 Jan 18. doi: 10.1186/s13064-018-0125-6

PMCID:: PMC6339399

Abstract Article PDF–1.6M

Select item 621659014.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 577732515.

Diversification of C. elegans motor neuron identity via selective effector gene repression

Sze Yen Kerk, Paschalis Kratsios, Michael Hart, Romulo Mourao, Oliver Hobert

Neuron. Author manuscript; available in PMC 2018 Jan 22.

Published in final edited form as: Neuron. 2017 Jan 4; 93(1): 80–98. doi: 10.1016/j.neuron.2016.11.036

PMCID:: PMC5777325

Abstract Article PDF–3.1M

Select item 549813516.

An intersectional gene regulatory strategy defines subclass diversity of C. elegans motor neurons

Paschalis Kratsios, Sze Yen Kerk, Catarina Catela, Joseph Liang, Berta Vidal, Emily A Bayer, Weidong Feng, Estanisla Daniel De La Cruz, Laura Croci, G Giacomo Consalez, Kota Mizumoto, Oliver Hobert

eLife. 2017; 6: e25751. Published online 2017 Jul 5. doi: 10.7554/eLife.25751