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Select item 112172921.

Neurons dispose of hyperactive kinesin into glial cells for clearance

Chao Xie, Guanghan Chen, Ming Li, Peng Huang, Zhe Chen, Kexin Lei, Dong Li, Yuhe Wang, Augustine Cleetus, Mohamed AA Mohamed, Punam Sonar, Wei Feng, Zeynep Ökten, Guangshuo Ou

EMBO J. 2024 Jul; 43(13): 2606–2635. Published online 2024 May 28. doi: 10.1038/s44318-024-00118-0

PMCID:: PMC11217292

Abstract Article PDF–6.6M

Select item 110433472.

IFT cargo and motors associate sequentially with IFT trains to enter cilia of C. elegans

Aniruddha Mitra, Elizaveta Loseva, Erwin J. G. Peterman

Nat Commun. 2024; 15: 3456. Published online 2024 Apr 24. doi: 10.1038/s41467-024-47807-2

PMCID:: PMC11043347

Abstract Article PDF–29M

Select item 109175243.

The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans

Robert A Brinzer, Alan D Winter, Antony P Page

G3 (Bethesda) 2024 Mar; 14(3): jkae009. Published online 2024 Jan 16. doi: 10.1093/g3journal/jkae009

PMCID:: PMC10917524

Abstract Article PDF–969K

Select item 106650134.

Specific sensory neurons and insulin-like peptides modulate food type-dependent oogenesis and fertilization in Caenorhabditis elegans

Shashwat Mishra, Mohamed Dabaja, Asra Akhlaq, Bianca Pereira, Kelsey Marbach, Mediha Rovcanin, Rashmi Chandra, Antonio Caballero, Diana Fernandes de Abreu, QueeLim Ch'ng, Joy Alcedo

eLife. 2023; 12: e83224. Published online 2023 Nov 17. doi: 10.7554/eLife.83224

PMCID:: PMC10665013

Abstract Article PDF–1.4M

Select item 103207665.

A transcriptional cofactor regulatory network for the C. elegans intestine

Brent B Horowitz, Shivani Nanda, Albertha J M Walhout

G3 (Bethesda) 2023 Jul; 13(7): jkad096. Published online 2023 Apr 29. doi: 10.1093/g3journal/jkad096

PMCID:: PMC10320766

Abstract Article PDF–1.9M

Select item 103199726.

Transcriptomic profiling of sex-specific olfactory neurons reveals subset-specific receptor expression in Caenorhabditis elegans

Douglas K Reilly, Erich M Schwarz, Caroline S Muirhead, Annalise N Robidoux, Anusha Narayan, Meenakshi K Doma, Paul W Sternberg, Jagan Srinivasan

Genetics. 2023 Apr; 223(4): iyad026. Published online 2023 Feb 18. doi: 10.1093/genetics/iyad026

PMCID:: PMC10319972

Abstract Article PDF–1.2M

Select item 100837267.

The sensory cilia of Caenorhabditis elegans.

Peter N Inglis, Guangshuo Ou, Michel R Leroux, Jonathan M Scholey

WormBook. 2007 Mar 8 : 1–22. Published online 2007 Mar 8. doi: 10.1895/wormbook.1.126.2

PMCID:: PMC10083726

Abstract Article

Select item 99580708.

Microfluidics and fluorescence microscopy protocol to study the response of C. elegans to chemosensory stimuli

Christine W. Bruggeman, Guus H. Haasnoot, Erwin J.G. Peterman

STAR Protoc. 2023 Mar 17; 4(1): 102121. Published online 2023 Feb 14. doi: 10.1016/j.xpro.2023.102121

PMCID:: PMC9958070

Abstract Article PDF–2.8M

Select item 95931899.

Kinesin-2 motors differentially impact biogenesis of extracellular vesicle subpopulations shed from sensory cilia

Michael Clupper, Rachael Gill, Malek Elsayyid, Denis Touroutine, Jeffrey L. Caplan, Jessica E. Tanis

iScience. 2022 Nov 18; 25(11): 105262. Published online 2022 Oct 4. doi: 10.1016/j.isci.2022.105262

PMCID:: PMC9593189

Abstract Article PDF–3.6M

Select item 953493010.

Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling

Alexandra Segref, Kavya L. Vakkayil, Tsimafei Padvitski, Qiaochu Li, Virginia Kroef, Jakob Lormann, Lioba Körner, Fabian Finger, Thorsten Hoppe

Nat Commun. 2022; 13: 5874. Published online 2022 Oct 5. doi: 10.1038/s41467-022-33467-7

PMCID:: PMC9534930

Abstract Article PDF–4.0M

Select item 938815011.

The physiological cargo adaptor of kinesin-2 functions as an evolutionary conserved lockpick

Augustine Cleetus, Georg Merck, Felix Mueller-Planitz, Zeynep Ökten

Proc Natl Acad Sci U S A. 2022 Aug 16; 119(33): e2109378119. Published online 2022 Aug 10. doi: 10.1073/pnas.2109378119

PMCID:: PMC9388150

Abstract Article PDF–1.5M

Select item 930072912.

A local interplay between diffusion and intraflagellar transport distributes TRPV-channel OCR-2 along C. elegans chemosensory cilia

Jaap van Krugten, Noémie Danné, Erwin J. G. Peterman

Commun Biol. 2022; 5: 720. Published online 2022 Jul 20. doi: 10.1038/s42003-022-03683-4

PMCID:: PMC9300729

Abstract Article PDF–1.9M

Select item 923309313.

A cilia-independent function of BBSome mediated by DLK MAPK signaling in C. elegans photosensation

Xinxing Zhang, Jinzhi Liu, Tong Pan, Alex Ward, Jianfeng Liu, X.Z. Shawn Xu

Dev Cell. Author manuscript; available in PMC 2023 Jun 20.

Published in final edited form as: Dev Cell. 2022 Jun 20; 57(12): 1545–1557.e4. Published online 2022 May 31. doi: 10.1016/j.devcel.2022.05.005

PMCID:: PMC9233093

Abstract Article PDF–1.1M

Select item 860931814.

Direct imaging of intraflagellar-transport turnarounds reveals that motors detach, diffuse, and reattach to opposite-direction trains

Zhiqing Zhang, Noémie Danné, Bonno Meddens, Iddo Heller, Erwin J. G. Peterman

Proc Natl Acad Sci U S A. 2021 Nov 9; 118(45): e2115089118. Published online 2021 Nov 3. doi: 10.1073/pnas.2115089118

PMCID:: PMC8609318

Abstract Article PDF–2.0M

Select item 857687115.

WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing

Ana R.G. De-Castro, Diogo R.M. Rodrigues, Maria J.G. De-Castro, Neide Vieira, Cármen Vieira, Ana X. Carvalho, Reto Gassmann, Carla M.C. Abreu, Tiago J. Dantas

J Cell Biol. 2022 Jan 3; 221(1): e202010178. Published online 2021 Nov 5. doi: 10.1083/jcb.202010178

PMCID:: PMC8576871

Abstract Article PDF–8.1M

Select item 849206116.

Ectocytosis prevents accumulation of ciliary cargo in C. elegans sensory neurons

Adria Razzauti, Patrick Laurent

eLife. 2021; 10: e67670. Published online 2021 Sep 17. doi: 10.7554/eLife.67670

PMCID:: PMC8492061

Abstract Article PDF–7.7M

Select item 840827617.

Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone

Douglas K. Reilly, Emily J. McGlame, Elke Vandewyer, Annalise N. Robidoux, Caroline S. Muirhead, Haylea T. Northcott, William Joyce, Mark J. Alkema, Robert J. Gegear, Isabel Beets, Jagan Srinivasan

Commun Biol. 2021; 4: 1018. Published online 2021 Aug 31. doi: 10.1038/s42003-021-02547-7

PMCID:: PMC8408276

Abstract Article PDF–2.6M

Select item 797975018.

The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing

Yincong Zhang, Xiaona Zhang, Yumin Dai, Mengjiao Song, Yifei Zhou, Jun Zhou, Xiumin Yan, Yidong Shen

Nat Commun. 2021; 12: 1789. Published online 2021 Mar 19. doi: 10.1038/s41467-021-22065-8

PMCID:: PMC7979750

Abstract Article PDF–4.2M

Select item 793123219.

Structural snapshots of the kinesin‐2 OSM‐3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism

Paloma F. Varela, Mélanie Chenon, Christophe Velours, Kristen J. Verhey, Julie Ménétrey, Benoît Gigant

FEBS Open Bio. 2021 Mar; 11(3): 564–577. Published online 2021 Feb 28. doi: 10.1002/2211-5463.13101

PMCID:: PMC7931232

Abstract Article PDF–7.6M

Select item 759291420.

Mutation of NEKL-4/NEK10 and TTLL genes suppress neuronal ciliary degeneration caused by loss of CCPP-1 deglutamylase function

Kade M. Power, Jyothi S. Akella, Amanda Gu, Jonathon D. Walsh, Sebastian Bellotti, Margaret Morash, Winnie Zhang, Yasmin H. Ramadan, Nicole Ross, Andy Golden, Harold E. Smith, Maureen M. Barr, Robert O’Hagan

PLoS Genet. 2020 Oct; 16(10): e1009052. Published online 2020 Oct 16. doi: 10.1371/journal.pgen.1009052