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Select item 93089461.

Treadmill exercise reduces α-synuclein spreading via PPARα

Debashis Dutta, Ramesh Kumar Paidi, Sumita Raha, Avik Roy, Sujyoti Chandra, Kalipada Pahan

Cell Rep. Author manuscript; available in PMC 2022 Jul 24.

Published in final edited form as: Cell Rep. 2022 Jul 12; 40(2): 111058. doi: 10.1016/j.celrep.2022.111058

Correction in:: Cell Rep. 2024 Aug 27; 43(8): 114546.

PMCID:: PMC9308946

Abstract Article PDF–3.2M

Select item 92470772.

p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1

So-Yoon Won, Jung-Jin Park, Soon-Tae You, Jong-A Hyeun, Hyong-Kyu Kim, Byung Kwan Jin, Catriona McLean, Eun-Young Shin, Eung-Gook Kim

Cell Death Dis. 2022 Jun; 13(6): 575. Published online 2022 Jun 30. doi: 10.1038/s41419-022-05030-1

PMCID:: PMC9247077

Abstract Article PDF–4.6M

Select item 83132393.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 81452974.

Preclinical Detection of Alpha-Synuclein Seeding Activity in the Colon of a Transgenic Mouse Model of Synucleinopathy by RT-QuIC

Jung-Youn Han, Chaewon Shin, Young Pyo Choi

Viruses. 2021 May; 13(5): 759. Published online 2021 Apr 26. doi: 10.3390/v13050759

PMCID:: PMC8145297

Abstract Article PDF–9.3M

Select item 80988145.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton

Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622

PMCID:: PMC8098814

Abstract Article PDF–7.7M

Select item 80240616.

Transglutaminase 2 Depletion Attenuates α-Synuclein Mediated Toxicity in Mice

Jie Zhang, Hilary Grosso Jasutkar, Run Yan, Jong-Min Woo, Kang-Woo Lee, Joo-Young Im, Eunsung Junn, Siiri E. Iismaa, M. Maral Mouradian

Neuroscience. Author manuscript; available in PMC 2021 Apr 6.

Published in final edited form as: Neuroscience. 2020 Aug 10; 441: 58–64. Published online 2020 Jun 2. doi: 10.1016/j.neuroscience.2020.05.047

PMCID:: PMC8024061

Abstract Article PDF–1.0M

Select item 68744447.

Dopaminergic neuron injury in Parkinson’s disease is mitigated by interfering lncRNA SNHG14 expression to regulate the miR-133b/ α-synuclein pathway

Li-Min Zhang, Meng-Han Wang, He-Cheng Yang, Tian Tian, Gui-Fang Sun, Yang-Fei Ji, Wen-Tao Hu, Xi Liu, Jian-Ping Wang, Hong Lu

Aging (Albany NY) 2019 Nov 15; 11(21): 9264–9279. Published online 2019 Nov 4. doi: 10.18632/aging.102330

PMCID:: PMC6874444

Abstract Article PDF–6.4M

Select item 64636518.

Neurodegeneration and contralateral α-synuclein induction after intracerebral α-synuclein injections in the anterior olfactory nucleus of a Parkinson’s disease A53T mouse model

Alicia Flores-Cuadrado, Daniel Saiz-Sanchez, Alicia Mohedano-Moriano, Alino Martinez-Marcos, Isabel Ubeda-Bañon

Acta Neuropathol Commun. 2019; 7: 56. Published online 2019 Apr 15. doi: 10.1186/s40478-019-0713-7

PMCID:: PMC6463651

Abstract Article PDF–5.5M

Select item 64241179.

Synphilin-1 exhibits trophic and protective effects against Rotenone toxicity

Xueping Li, Zhaohui Liu, Kellie Tamashiro, Bingyin Shi, Dobrila D. Rudnicki, Christopher A. Ross, Timothy H. Moran, Wanli W. Smith

Neuroscience. Author manuscript; available in PMC 2019 Mar 19.

Published in final edited form as: Neuroscience. 2010 Jan 20; 165(2): 455–462. doi: 10.1016/j.neuroscience.2009.10.042

PMCID:: PMC6424117

Abstract Article PDF–670K

Select item 630928310.

TCDD induces UbcH7 expression and synphilin-1 protein degradation in the mouse ventral midbrain

Emmanuel González-Barbosa, Alejandro Mejía-García, Elizabeth Bautista, Frank J. Gonzalez, José Segovia, Guillermo Elizondo

J Biochem Mol Toxicol. Author manuscript; available in PMC 2018 Dec 28.

Published in final edited form as: J Biochem Mol Toxicol. 2017 Oct; 31(10): 10.1002/jbt.21947. Published online 2017 Jun 16. doi: 10.1002/jbt.21947

PMCID:: PMC6309283

Abstract Article PDF–1.4M

Select item 594657411.

A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson’s disease-like pathology in neurons and glia

Martin Timo Henrich, Fanni Fruzsina Geibl, Bolam Lee, Wei-Hua Chiu, James Benjamin Koprich, Jonathan Michael Brotchie, Lars Timmermann, Niels Decher, Lina Anita Matschke, Wolfgang Hermann Oertel

Acta Neuropathol Commun. 2018; 6: 39. Published online 2018 May 10. doi: 10.1186/s40478-018-0541-1

PMCID:: PMC5946574

Abstract Article PDF–7.4M

Select item 586993812.

Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice

Martin Regensburger, Sebastian R. Schreglmann, Svenja Stoll, Edward Rockenstein, Sandra Loskarn, Wei Xiang, Eliezer Masliah, Beate Winner

Brain Struct Funct. 2018; 223(3): 1357–1368. Published online 2017 Nov 9. doi: 10.1007/s00429-017-1561-5

PMCID:: PMC5869938

Abstract Article PDF–1.8M

Select item 496178113.

Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model

Brian Spencer, Paula A. Desplats, Cassia R. Overk, Elvira Valera-Martin, Robert A. Rissman, Chengbiao Wu, Michael Mante, Anthony Adame, Jazmin Florio, Edward Rockenstein, Eliezer Masliah

J Neurosci. 2016 Jul 27; 36(30): 7971–7984. doi: 10.1523/JNEUROSCI.0775-16.2016

PMCID:: PMC4961781

Abstract Article PDF–5.7M

Select item 466892514.

α-synuclein expression in the mouse cerebellum is restricted to VGluT1 excitatory terminals and is enriched in unipolar brush cells

Sun Kyong Lee, Roy V. Sillitoe, Coralie Silva, Marco Martina, Gabriella Sekerkova

Cerebellum. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Cerebellum. 2015 Oct; 14(5): 516–527. doi: 10.1007/s12311-015-0673-9

PMCID:: PMC4668925

Abstract Article PDF–4.5M

Select item 464649815.

CCK Response Deficiency in Synphilin-1 Transgenic Mice

Wanli W. Smith, Megan Smith, Dejun Yang, Pique P. Choi, Alexander Moghadam, Tianxia Li, Timothy H. Moran

PLoS One. 2015; 10(11): e0142314. Published online 2015 Nov 16. doi: 10.1371/journal.pone.0142314

PMCID:: PMC4646498

Abstract Article PDF–1.5M

Select item 436552716.

Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity

Wei Xiang, Stefanie Menges, Johannes CM Schlachetzki, Holger Meixner, Anna-Carin Hoffmann, Ursula Schlötzer-Schrehardt, Cord-Michael Becker, Jürgen Winkler, Jochen Klucken

Mol Neurodegener. 2015; 10: 8. Published online 2015 Mar 11. doi: 10.1186/s13024-015-0004-0

PMCID:: PMC4365527

Abstract Article PDF–3.3M

Select item 406435817.

Atomic force microscopy based nanoassay: a new method to study α-Synuclein-dopamine bioaffinity interactions

Stefania Corvaglia, Barbara Sanavio, Rolando P. Hong Enriquez, Barbara Sorce, Alessandro Bosco, Denis Scaini, Stefania Sabella, Pier Paolo Pompa, Giacinto Scoles, Loredana Casalis

Sci Rep. 2014; 4: 5366. Published online 2014 Jun 20. doi: 10.1038/srep05366

PMCID:: PMC4064358

Abstract Article PDF–1.3M

Select item 357241018.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 352739119.

The Guanine Nucleotide Exchange Factor Kalirin-7 Is a Novel Synphilin-1 Interacting Protein and Modifies Synphilin-1 Aggregate Transport and Formation

Yu-Chun Tsai, Olaf Riess, Anne S. Soehn, Huu Phuc Nguyen

PLoS One. 2012; 7(12): e51999. Published online 2012 Dec 20. doi: 10.1371/journal.pone.0051999

PMCID:: PMC3527391

Abstract Article PDF–5.8M

Select item 343955220.

A novel obesity model: Synphilin-1 induced hyperphagia and obesity in mice

Xueping Li, Kellie LK. Tamashiro, Zhaohui Liu, Nicholas T Bello, Xiaofang Wang, Susan Aja, Sheng Bi, Ellen E. Ladenheim, Christopher, A. Ross, Timothy H. Moran, Wanli W. Smith

Int J Obes (Lond) Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Int J Obes (Lond). 2012 Sep; 36(9): 1215–1221. Published online 2011 Dec 13. doi: 10.1038/ijo.2011.235