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Select item 108029521.

Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly

Marcos Schaan Profes, Araven Tiroumalechetty, Neel Patel, Stephanie S. Lauar, Simone Sidoli, Peri T. Kurshan

PLoS Biol. 2024 Jan; 22(1): e3002466. Published online 2024 Jan 22. doi: 10.1371/journal.pbio.3002466

PMCID:: PMC10802952

Abstract Article PDF–2.7M

Select item 99506602.

Peroxiredoxin 2 is required for the redox mediated adaptation to exercise

Qin Xia, Jose C. Casas-Martinez, Eduardo Zarzuela, Javier Muñoz, Antonio Miranda-Vizuete, Katarzyna Goljanek-Whysall, Brian McDonagh

Redox Biol. 2023 Apr; 60: 102631. Published online 2023 Feb 9. doi: 10.1016/j.redox.2023.102631

PMCID:: PMC9950660

Abstract Article PDF–15M

Select item 97092423.

Mitochondrial succinate dehydrogenase function is essential for sperm motility and male fertility

Rachel M. Woodhouse, Natalya Frolows, Guoqiang Wang, Azelle Hawdon, Edmund Heng Kin Wong, Linda C. Dansereau, Yingying Su, Liam D. Adair, Elizabeth J. New, Ashleigh M. Philp, Wei Kang Tan, Andrew Philp, Alyson Ashe

iScience. 2022 Dec 22; 25(12): 105573. Published online 2022 Nov 14. doi: 10.1016/j.isci.2022.105573

PMCID:: PMC9709242

Abstract Article PDF–6.3M

Select item 94378484.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 93713565.

The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespan

İçten Meraş, Laëtitia Chotard, Thomas Liontis, Zakaria Ratemi, Benjamin Wiles, Jung Hwa Seo, Jeremy M. Van Raamsdonk, Christian E. Rocheleau

PLoS Genet. 2022 Aug; 18(8): e1010328. Published online 2022 Aug 1. doi: 10.1371/journal.pgen.1010328

PMCID:: PMC9371356

Abstract Article PDF–3.3M

Select item 90207166.

A modified TurboID approach identifies tissue-specific centriolar components in C. elegans

Elisabeth Holzer, Cornelia Rumpf-Kienzl, Sebastian Falk, Alexander Dammermann

PLoS Genet. 2022 Apr; 18(4): e1010150. Published online 2022 Apr 20. doi: 10.1371/journal.pgen.1010150

Correction in:: PLoS Genet. 2023 Feb; 19(2): e1010645.

PMCID:: PMC9020716

Abstract Article PDF–2.0M

Select item 88140267.

Mitochondrial protein import determines lifespan through metabolic reprogramming and de novo serine biosynthesis

Eirini Lionaki, Ilias Gkikas, Ioanna Daskalaki, Maria-Konstantina Ioannidi, Maria I. Klapa, Nektarios Tavernarakis

Nat Commun. 2022; 13: 651. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28272-1

PMCID:: PMC8814026

Abstract Article PDF–2.3M

Select item 84467938.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 83311839.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 799517610.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 775030311.

Multiple metabolic changes mediate the response of Caenorhabditis elegans to the complex I inhibitor rotenone

Claudia P. Gonzalez-Hunt, Anthony L. Luz, Ian T. Ryde, Elena A. Turner, Olga R. Ilkayeva, Dhaval P. Bhatt, Matthew D. Hirschey, Joel N. Meyer

Toxicology. Author manuscript; available in PMC 2022 Jan 15.

Published in final edited form as: Toxicology. 2021 Jan 15; 447: 152630. Published online 2020 Nov 11. doi: 10.1016/j.tox.2020.152630

PMCID:: PMC7750303

Abstract Article PDF–717K

Select item 711515912.

Succinate Dehydrogenase-Regulated Phosphoenolpyruvate Carboxykinase Sustains Copulation Fitness in Aging C. elegans Males

Jimmy Goncalves, Yufeng Wan, Xiaoyan Guo, Kyoungsun Rha, Brigitte LeBoeuf, Liusuo Zhang, Kerolayne Estler, L. René Garcia

iScience. 2020 Apr 24; 23(4): 100990. Published online 2020 Mar 19. doi: 10.1016/j.isci.2020.100990

PMCID:: PMC7115159

Abstract Article PDF–8.6M

Select item 682614513.

The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans

Stefanie Müthel, Bora Uyar, Mei He, Anne Krause, Burcu Vitrinel, Selman Bulut, Djordje Vasiljevic, Iris Marchal, Stefan Kempa, Altuna Akalin, Baris Tursun

Aging Cell. 2019 Dec; 18(6): e13012. Published online 2019 Aug 9. doi: 10.1111/acel.13012

PMCID:: PMC6826145

Abstract Article PDF–3.0M

Select item 574105614.

Genome-wide discovery of active regulatory elements and transcription factor footprints in Caenorhabditis elegans using DNase-seq

Margaret C.W. Ho, Porfirio Quintero-Cadena, Paul W. Sternberg

Genome Res. 2017 Dec; 27(12): 2108–2119. doi: 10.1101/gr.223735.117

PMCID:: PMC5741056

Abstract Article PDF–11M

Select item 565512515.

daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival

Jonathan D Hibshman, Alexander E Doan, Brad T Moore, Rebecca EW Kaplan, Anthony Hung, Amy K Webster, Dhaval P Bhatt, Rojin Chitrakar, Matthew D Hirschey, L Ryan Baugh

eLife. 2017; 6: e30057. Published online 2017 Oct 24. doi: 10.7554/eLife.30057