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Select item 111444381.

Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes

Huei-Ying Chen, BaDoi N. Phan, Gina Shim, Gregory R. Hamersky, Norah Sadowski, Thomas S. O’Donnell, Srinidhi Rao Sripathy, Joseph F. Bohlen, Andreas R. Pfenning, Brady J. Maher

Mol Psychiatry. Author manuscript; available in PMC 2024 Jun 2.

Published in final edited form as: Mol Psychiatry. 2023 Nov; 28(11): 4679–4692. Published online 2023 Sep 28. doi: 10.1038/s41380-023-02248-z

PMCID:: PMC11144438

Abstract Article PDF–2.3M

Select item 111418732.

Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling

Yanyun Jiang, Dennis Gruszka, Chang Zeng, William R. Swindell, Christa Gaskill, Christian Sorensen, Whitney Brown, Roopesh Singh Gangwar, Lam C. Tsoi, Joshua Webster, Sigrún Laufey Sigurðardóttir, Mrinal K. Sarkar, Ranjitha Uppala, Austin Kidder, Xianying Xing, Olesya Plazyo, Enze Xing, Allison C. Billi, Emanual Maverakis, J. Michelle Kahlenberg, Johann E. Gudjonsson, Nicole L. Ward

JCI Insight. 2024 Apr 22; 9(8): e172764. Published online 2024 Mar 12. doi: 10.1172/jci.insight.172764

PMCID:: PMC11141873

Abstract Article PDF–16M

Select item 110195563.

Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities

Hong Li, Ying Zhu, Yury M. Morozov, Xiaoli Chen, Stephanie Cerceo Page, Matthew D. Rannals, Brady J. Maher, Pasko Rakic

Mol Psychiatry. Author manuscript; available in PMC 2024 Apr 16.

Published in final edited form as: Mol Psychiatry. 2019 Aug; 24(8): 1235–1246. Published online 2019 Jan 31. doi: 10.1038/s41380-019-0353-0

PMCID:: PMC11019556

Abstract Article PDF–1.7M

Select item 109666794.

A GFP–Tcf4 reporter mouse model for monitoring effects of Apc mutations during intestinal tumorigenesis

Bruce Boman, Levy Kopelovich, Linda Siracusa, Tao Zhang, Kim Henderson, Zenobia Cofer, Arthur Buchberg, Jeremy Z. Fields, Tomas Otevrel

Mol Carcinog. Author manuscript; available in PMC 2024 Mar 27.

Published in final edited form as: Mol Carcinog. 2009 Sep; 48(9): 821–831. doi: 10.1002/mc.20526

PMCID:: PMC10966679

Abstract Article PDF–1.6M

Select item 109176605.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105454376.

DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons

Arquimedes Cheffer, Marta Garcia-Miralles, Esther Maier, Ipek Akol, Henriette Franz, Vandana Shree Vedartham Srinivasan, Tanja Vogel

Cereb Cortex. 2023 Oct 1; 33(19): 10272–10285. Published online 2023 Aug 11. doi: 10.1093/cercor/bhad281

PMCID:: PMC10545437

Abstract Article PDF–2.8M

Select item 104859567.

Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon

Mary Jo Talley, Diana Nardini, Lisa A. Ehrman, Q. Richard Lu, Ronald R. Waclaw

Neural Dev. 2023; 18: 5. Published online 2023 Sep 8. doi: 10.1186/s13064-023-00173-z

PMCID:: PMC10485956

Abstract Article PDF–15M

Select item 101300908.

Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development

Mingyu Lee, Yi-Sook Kim, Suha Lim, Seung-Hyun Shin, Iljin Kim, Jiyoung Kim, Min Choi, Jung Ho Kim, Seong-Joon Koh, Jong-Wan Park, Hyun-Woo Shin

Nat Commun. 2023; 14: 2363. Published online 2023 Apr 25. doi: 10.1038/s41467-023-38080-w

PMCID:: PMC10130090

Abstract Article PDF–8.4M

Select item 98457439.

ID1 and CEBPA coordinate epidermal progenitor cell differentiation

Christina Geraldine Kantzer, Wei Yang, David Grommisch, Kim Vikhe Patil, Kylie Hin-Man Mak, Vera Shirokova, Maria Genander

Development. 2022 Nov 15; 149(22): dev201262. Published online 2022 Nov 16. doi: 10.1242/dev.201262

PMCID:: PMC9845743

Abstract Article

Select item 966640510.

Expression of alternative transcription factor 4 mRNAs and protein isoforms in the developing and adult rodent and human tissues

Alex Sirp, Anastassia Shubina, Jürgen Tuvikene, Laura Tamberg, Carl Sander Kiir, Laura Kranich, Tõnis Timmusk

Front Mol Neurosci. 2022; 15: 1033224. Published online 2022 Nov 2. doi: 10.3389/fnmol.2022.1033224

PMCID:: PMC9666405

Abstract Article PDF–8.6M

Select item 948193311.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 909032412.

Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of Tcf4 expression

Hyojin Kim, Eric B Gao, Adam Draper, Noah C Berens, Hanna Vihma, Xinyuan Zhang, Alexandra Higashi-Howard, Kimberly D Ritola, Jeremy M Simon, Andrew J Kennedy, Benjamin D Philpot

eLife. 2022; 11: e72290. Published online 2022 May 10. doi: 10.7554/eLife.72290

PMCID:: PMC9090324

Abstract Article PDF–11M

Select item 895613413.

A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior

Joseph R. Knoedler, Sayaka Inoue, Daniel W. Bayless, Taehong Yang, Adarsh Tantry, Chung-ha Davis, Nicole Y. Leung, Srinivas Parthasarathy, Grace Wang, Maricruz Alvarado, Abbas H. Rizvi, Lief E. Fenno, Charu Ramakrishnan, Karl Deisseroth, Nirao M. Shah

Cell. Author manuscript; available in PMC 2023 Feb 17.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 654–671.e22. Published online 2022 Jan 21. doi: 10.1016/j.cell.2021.12.031

Correction in:: Cell. 2024 Jul 11; 187(14): 3781.

PMCID:: PMC8956134

Abstract Article PDF–4.6M

Select item 888790314.

Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain

Dongjin R Lee, Christopher Rhodes, Apratim Mitra, Yajun Zhang, Dragan Maric, Ryan K Dale, Timothy J Petros

eLife. 2022; 11: e71864. Published online 2022 Feb 17. doi: 10.7554/eLife.71864

PMCID:: PMC8887903

Abstract Article PDF–15M

Select item 871379415.

Transcriptional network orchestrating regional patterning of cortical progenitors

Athéna R. Ypsilanti, Kartik Pattabiraman, Rinaldo Catta-Preta, Olga Golonzhka, Susan Lindtner, Ke Tang, Ian R. Jones, Armen Abnousi, Ivan Juric, Ming Hu, Yin Shen, Diane E. Dickel, Axel Visel, Len A. Pennacchio, Michael Hawrylycz, Carol L. Thompson, Hongkui Zeng, Iros Barozzi, Alex S. Nord, John L. Rubenstein

Proc Natl Acad Sci U S A. 2021 Dec 21; 118(51): e2024795118. Published online 2021 Dec 17. doi: 10.1073/pnas.2024795118

PMCID:: PMC8713794

Abstract Article PDF–3.1M

Select item 867775316.

TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4

Hao Wang, Wei Wei, Zhong-Yuan Zhang, Yao Liu, Bin Shi, Wen Zhong, Hou-Shun Zhang, Xin Fang, Chun-Lei Sun, Jia-Bei Wang, Lian-Xin Liu

Cell Death Dis. 2022 Jan; 13(1): 3. Published online 2021 Dec 17. doi: 10.1038/s41419-021-04459-0

PMCID:: PMC8677753

Abstract Article PDF–6.2M

Select item 860040817.

MicroRNA-190b expression predicts a good prognosis and attenuates the malignant progression of pancreatic cancer by targeting MEF2C and TCF4

Yunwei Li, Zhe Wang, Feng Zhao, Juan Zeng, Xianghong Yang

Oncol Rep. 2022 Jan; 47(1): 12. Published online 2021 Nov 10. doi: 10.3892/or.2021.8223

PMCID:: PMC8600408

Abstract Article PDF–1.0M

Select item 851930618.

Isoform-Specific Reduction of the Basic Helix-Loop-Helix Transcription Factor TCF4 Levels in Huntington’s Disease

Kaja Nurm, Mari Sepp, Carla Castany-Pladevall, Jordi Creus-Muncunill, Jürgen Tuvikene, Alex Sirp, Hanna Vihma, Derek J. Blake, Esther Perez-Navarro, Tõnis Timmusk

eNeuro. 2021 Sep-Oct; 8(5): ENEURO.0197-21.2021. Prepublished online 2021 Sep 13. Published online 2021 Oct 13. doi: 10.1523/ENEURO.0197-21.2021

PMCID:: PMC8519306

Abstract Article PDF–1.4M

Select item 851457519.

Disordered breathing in a Pitt-Hopkins syndrome model involves Phox2b-expressing parafacial neurons and aberrant Nav1.8 expression

C. M. Cleary, S. James, B. J. Maher, D. K. Mulkey

Nat Commun. 2021; 12: 5962. Published online 2021 Oct 13. doi: 10.1038/s41467-021-26263-2

PMCID:: PMC8514575

Abstract Article PDF–3.5M

Select item 832718620.

scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse

Marie-Theres Wittmann, Sayako Katada, Elisabeth Sock, Philipp Kirchner, Arif B. Ekici, Michael Wegner, Kinichi Nakashima, Dieter Chichung Lie, André Reis

Development. 2021 Jul 15; 148(14): dev196022. Published online 2021 Jul 19. doi: 10.1242/dev.196022

PMCID:: PMC8327186

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