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Select item 116605261.

The role of ATP citrate lyase in myelin formation and maintenance

Andrew Schneider, Seongsik Won, Eric A. Armstrong, Aaron J. Cooper, Amulya Suresh, Rachell Rivera, Gregory Barrett‐Wilt, John M. Denu, Judith A. Simcox, John Svaren

Glia. 2025 Jan; 73(1): 105–121. Published online 2024 Sep 25. doi: 10.1002/glia.24620

PMCID:: PMC11660526

Article PDF–4.3M

Select item 113580072.

Nuclear ATP-citrate lyase regulates chromatin-dependent activation and maintenance of the myofibroblast gene program

Michael P. Lazaropoulos, Andrew A. Gibb, Douglas J. Chapski, Abheya A. Nair, Allison N. Reiter, Rajika Roy, Deborah M. Eaton, Kenneth C. Bedi, Jr, Kenneth B. Margulies, Kathryn E. Wellen, Conchi Estarás, Thomas M. Vondriska, John W. Elrod

Nat Cardiovasc Res. 2024; 3(7): 869–882. Published online 2024 Jul 5. doi: 10.1038/s44161-024-00502-3

PMCID:: PMC11358007

Article PDF–7.9M

Select item 112608533.

ACLY alternative splicing correlates with cancer phenotypes

Julianna G. Supplee, Hayley C. Affronti, Richard Duan, Rebekah C. Brooks, Zachary E. Stine, Phuong T.T. Nguyen, Laura V. Pinheiro, Michael C. Noji, Jack M. Drummond, Kevin Huang, Kollin Schultz, Chi V. Dang, Ronen Marmorstein, Kathryn E. Wellen

J Biol Chem. 2024 Jul; 300(7): 107418. Published online 2024 May 28. doi: 10.1016/j.jbc.2024.107418

PMCID:: PMC11260853

Article PDF–4.1M

Select item 106763604.

Acetyl-CoA is a key molecule for nephron progenitor cell pool maintenance

Fabiola Diniz, Nguyen Yen Nhi Ngo, Mariel Colon-Leyva, Francesca Edgington-Giordano, Sylvia Hilliard, Kevin Zwezdaryk, Jiao Liu, Samir S. El-Dahr, Giovane G. Tortelote

Nat Commun. 2023; 14: 7733. Published online 2023 Nov 25. doi: 10.1038/s41467-023-43513-7

PMCID:: PMC10676360

Article PDF–12M

Select item 105509955.

Cytoplasmic Endonuclease G promotes nonalcoholic fatty liver disease via mTORC2-AKT-ACLY and endoplasmic reticulum stress

Wenjun Wang, Junyang Tan, Xiaomin Liu, Wenqi Guo, Mengmeng Li, Xinjie Liu, Yanyan Liu, Wenyu Dai, Liubing Hu, Yimin Wang, Qiuxia Lu, Wen Xing Lee, Hong-Wen Tang, Qinghua Zhou

Nat Commun. 2023; 14: 6201. Published online 2023 Oct 4. doi: 10.1038/s41467-023-41757-x

Correction in:: Nat Commun. 2024; 15: 7167.

PMCID:: PMC10550995

Article PDF–3.0M

Select item 103078526.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Article PDF–8.8M

Select item 102861057.

Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program

Adilson Guilherme, Leslie A. Rowland, Nicole Wetoska, Emmanouela Tsagkaraki, Kaltinaitis B. Santos, Alexander H. Bedard, Felipe Henriques, Mark Kelly, Sean Munroe, David J. Pedersen, Olga R. Ilkayeva, Timothy R. Koves, Lauren Tauer, Meixia Pan, Xianlin Han, Jason K. Kim, Christopher B. Newgard, Deborah M. Muoio, Michael P. Czech

Cell Rep. Author manuscript; available in PMC 2023 Jun 22.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112488. Published online 2023 May 8. doi: 10.1016/j.celrep.2023.112488

PMCID:: PMC10286105

Article PDF–3.3M

Select item 96038608.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Article PDF–3.4M

Select item 94905929.

Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice

Batuhan Yenilmez, Mark Kelly, Guo-Fang Zhang, Nicole Wetoska, Olga R. Ilkayeva, Kyounghee Min, Leslie Rowland, Chloe DiMarzio, Wentao He, Naideline Raymond, Lawrence Lifshitz, Meixia Pan, Xianlin Han, Jun Xie, Randall H. Friedline, Jason K. Kim, Guangping Gao, Mark A. Herman, Christopher B. Newgard, Michael P. Czech

J Biol Chem. 2022 Oct; 298(10): 102401. Published online 2022 Aug 18. doi: 10.1016/j.jbc.2022.102401

PMCID:: PMC9490592

Article PDF–1.6M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Article PDF–3.5M

Select item 938646411.

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang

Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548

PMCID:: PMC9386464

Article PDF–6.6M

Select item 901906512.

The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming

Sophia M. Hochrein, Hao Wu, Miriam Eckstein, Laura Arrigoni, Josip S. Herman, Fabian Schumacher, Christian Gerecke, Mathias Rosenfeldt, Dominic Grün, Burkhard Kleuser, Georg Gasteiger, Wolfgang Kastenmüller, Bart Ghesquière, Jan Van den Bossche, E. Dale Abel, Martin Vaeth

Cell Metab. Author manuscript; available in PMC 2023 Apr 5.

Published in final edited form as: Cell Metab. 2022 Apr 5; 34(4): 516–532.e11. Published online 2022 Mar 21. doi: 10.1016/j.cmet.2022.02.015

PMCID:: PMC9019065

Article PDF–1.8M

Select item 883246113.

DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis

Yanchuan Li, Xiaoping Xie, Zuliang Jie, Lele Zhu, Jin-Young Yang, Chun-Jung Ko, Tianxiao Gao, Antrix Jain, Sung Yun Jung, Natalia Baran, Marina Y. Konopleva, Xuhong Cheng, Shao-Cong Sun

Blood. 2021 Dec 9; 138(23): 2360–2371. doi: 10.1182/blood.2021011247

PMCID:: PMC8832461

Article

Select item 877727614.

PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway

Nianyin Lv, Sufeng Jin, Zihao Liang, Xiaohui Wu, Yanhua Kang, Lan Su, Yeping Dong, Bingwei Wang, Tonghui Ma, Liyun Shi

Front Immunol. 2021; 12: 751409. Published online 2022 Jan 7. doi: 10.3389/fimmu.2021.751409

PMCID:: PMC8777276

Article PDF–10M

Select item 858931615.

Lactate supports a metabolic-epigenetic link in macrophage polarization

Jordan T. Noe, Beatriz E. Rendon, Anne E. Geller, Lindsey R. Conroy, Samantha M. Morrissey, Lyndsay E.A. Young, Ronald C. Bruntz, Eun J. Kim, Ashley Wise-Mitchell, Mariana Barbosa de Souza Rizzo, Eric R. Relich, Becca V. Baby, Lance A. Johnson, Hayley C. Affronti, Kelly M. McMasters, Brian F. Clem, Matthew S. Gentry, Jun Yan, Kathryn E. Wellen, Ramon C. Sun, Robert A. Mitchell

Sci Adv. 2021 Nov; 7(46): eabi8602. Published online 2021 Nov 12. doi: 10.1126/sciadv.abi8602

PMCID:: PMC8589316

Article PDF–2.6M

Select item 849760616.

ATP-citrate lyase promotes axonal transport across species

Aviel Even, Giovanni Morelli, Silvia Turchetto, Michal Shilian, Romain Le Bail, Sophie Laguesse, Nathalie Krusy, Ariel Brisker, Alexander Brandis, Shani Inbar, Alain Chariot, Frédéric Saudou, Paula Dietrich, Ioannis Dragatsis, Bert Brone, Loïc Broix, Jean-Michel Rigo, Miguel Weil, Laurent Nguyen

Nat Commun. 2021; 12: 5878. Published online 2021 Oct 7. doi: 10.1038/s41467-021-25786-y

Correction in:: Nat Commun. 2021; 12: 6678.

PMCID:: PMC8497606

Article PDF–5.3M

Select item 842344517.

ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation

Miaomiao Tian, Fengqi Hao, Xin Jin, Xue Sun, Ying Jiang, Yang Wang, Dan Li, Tianyi Chang, Yingying Zou, Pinghui Peng, Chaoyi Xia, Jia Liu, Yuanxi Li, Ping Wang, Yunpeng Feng, Min Wei

eLife. 2021; 10: e62394. Published online 2021 Sep 7. doi: 10.7554/eLife.62394

PMCID:: PMC8423445

Article PDF–1.2M

Select item 831323918.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Article PDF–1.6M

Select item 816268619.

PEG3 controls lipogenesis through ACLY

Subash Ghimire, Joomyeong Kim

PLoS One. 2021; 16(5): e0252354. Published online 2021 May 28. doi: 10.1371/journal.pone.0252354

PMCID:: PMC8162686

Article PDF–2.3M

Select item 810772220.

Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes

Sanne G. S. Verberk, Hendrik J. P. van der Zande, Jeroen Baardman, Kyra E. de Goede, Karl J. Harber, Eelco D. Keuning, Joost M. Lambooij, Frank Otto, Anna Zawistowska-Deniziak, Helga E. de Vries, Menno P. J. de Winther, Bruno Guigas, Jan Van den Bossche

Front Immunol. 2021; 12: 669920. Published online 2021 Apr 26. doi: 10.3389/fimmu.2021.669920

PMCID:: PMC8107722

Article PDF–7.9M

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