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Items: 1 to 20 of 49

1.
Behavioral and cortical arousal from sleep, muscimol-induced coma, and anesthesia by direct optogenetic stimulation of cortical neurons
Rong Mao, Matias Lorenzo Cavelli, Graham Findlay, Kort Driessen, Michael J. Peterson, William Marshall, Giulio Tononi, Chiara Cirelli
iScience. 2024 Jun 21; 27(6): 109919. Published online 2024 May 7. doi: 10.1016/j.isci.2024.109919
PMCID:
PMC11134913
AbstractArticlePDF–9.5M
2.
Adaptation of sequential action benefits from timing variability related to lateral basal ganglia circuitry
Lachlan A. Ferguson, Miriam Matamales, Christopher Nolan, Bernard W. Balleine, Jesus Bertran-Gonzalez
iScience. 2024 Mar 15; 27(3): 109274. Published online 2024 Feb 20. doi: 10.1016/j.isci.2024.109274
PMCID:
PMC10943431
AbstractArticlePDF–28M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Intestinal transit-amplifying cells require METTL3 for growth factor signaling and cell survival
Charles H. Danan, Kaitlyn E. Naughton, Katharina E. Hayer, Sangeevan Vellappan, Emily A. McMillan, Yusen Zhou, Rina Matsuda, Shaneice K. Nettleford, Kay Katada, Louis R. Parham, Xianghui Ma, Afrah Chowdhury, Benjamin J. Wilkins, Premal Shah, Matthew D. Weitzman, Kathryn E. Hamilton
JCI Insight. 2023 Dec 8; 8(23): e171657. Published online 2023 Dec 8. doi: 10.1172/jci.insight.171657
PMCID:
PMC10795831
AbstractArticlePDF–5.8M
5.
δ-Catenin controls astrocyte morphogenesis via layer-specific astrocyte–neuron cadherin interactions
Christabel Xin Tan, Dhanesh Sivadasan Bindu, Evelyn J. Hardin, Kristina Sakers, Ryan Baumert, Juan J. Ramirez, Justin T. Savage, Cagla Eroglu
J Cell Biol. 2023 Nov 6; 222(11): e202303138. Published online 2023 Sep 14. doi: 10.1083/jcb.202303138
PMCID:
PMC10501387
AbstractArticlePDF–8.5M
6.
A genetically targeted ion sensor reveals distinct seizure-related chloride and pH dynamics in GABAergic interneuron populations
Alexandru Călin, Tatiana Waseem, Joseph V. Raimondo, Sarah E. Newey, Colin J. Akerman
iScience. 2023 Apr 21; 26(4): 106363. Published online 2023 Mar 9. doi: 10.1016/j.isci.2023.106363
PMCID:
PMC10074576
AbstractArticlePDF–5.8M
7.
Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning
Yukie Yamahashi, You-Hsin Lin, Akihiro Mouri, Sho Iwanaga, Kazuhiro Kawashima, Yuya Tokumoto, Yo Watanabe, Md. Omar Faruk, Xinjian Zhang, Daisuke Tsuboi, Takashi Nakano, Naoaki Saito, Taku Nagai, Kiyofumi Yamada, Kozo Kaibuchi
Mol Psychiatry. 2022; 27(8): 3479–3492. Published online 2022 Jun 3. doi: 10.1038/s41380-022-01643-2
PMCID:
PMC9708603
AbstractArticlePDF–3.0M
8.
Tonic activity in lateral habenula neurons acts as a neutral valence brake on reward-seeking behavior
Ryan J. Post, David A. Bulkin, R. Becket Ebitz, Vladlena Lee, Kasey Han, Melissa R. Warden
Curr Biol. Author manuscript; available in PMC 2023 Oct 24.
Published in final edited form as: Curr Biol. 2022 Oct 24; 32(20): 4325–4336.e5. Published online 2022 Aug 31. doi: 10.1016/j.cub.2022.08.016
PMCID:
PMC9613558
AbstractArticlePDF–2.5M
9.
Inducing and measuring apoptotic cell death in mouse pancreatic β-cells and in isolated islets
Wendy M. McKimpson, Richard N. Kitsis
STAR Protoc. 2022 Jun 17; 3(2): 101287. Published online 2022 Apr 11. doi: 10.1016/j.xpro.2022.101287
PMCID:
PMC9200107
AbstractArticlePDF–3.5M
10.
Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies
Daniel J Rawle, Thuy T Le, Troy Dumenil, Cameron Bishop, Kexin Yan, Eri Nakayama, Phillip I Bird, Andreas Suhrbier
eLife. 2022; 11: e70207. Published online 2022 Feb 4. doi: 10.7554/eLife.70207
PMCID:
PMC8816380
AbstractArticlePDF–7.7M
11.
IL-23/IL-17A/TRPV1 Axis Produces Mechanical Pain via Macrophage-Sensory Neuron Crosstalk in Female Mice
Xin Luo, Ouyang Chen, Zilong Wang, Sangsu Bang, Jasmine Ji, Sang Hoon Lee, Yul Huh, Kenta Furutani, Qianru He, Xueshu Tao, Mei-Chuan Ko, Andrey Bortsov, Christopher R Donnelly, Yong Chen, Andrea Nackley, Temugin Berta, Ru-Rong Ji
Neuron. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Neuron. 2021 Sep 1; 109(17): 2691–2706.e5. Published online 2021 Jul 19. doi: 10.1016/j.neuron.2021.06.015
PMCID:
PMC8425601
AbstractArticlePDF–5.1M
12.
NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism
Jennifer Allouche, Inbal Rachmin, Kaustubh Adhikari, Luba M. Pardo, Ju Hee Lee, Alicia M. McConnell, Shinichiro Kato, Shaohua Fan, Akinori Kawakami, Yusuke Suita, Kazumasa Wakamatsu, Vivien Igras, Jianming Zhang, Paula P. Navarro, Camila Makhlouta Lugo, Haley R. Noonan, Kathleen A. Christie, Kaspar Itin, Nisma Mujahid, Jennifer A. Lo, Chong Hyun Won, Conor L. Evans, Qing Yu Weng, Hequn Wang, Sam Osseiran, Alyssa Lovas, István Németh, Antonio Cozzio, Alexander A. Navarini, Jennifer J. Hsiao, Nhu Nguyen, Lajos V. Kemény, Othon Iliopoulos, Carola Berking, Thomas Ruzicka, Rolando Gonzalez-José, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Victor Acuna-Alonso, Carla Gallo, Giovanni Poletti, Gabriel Bedoya, Francisco Rothhammer, Shosuke Ito, Maria Vittoria Schiaffino, Luke H. Chao, Benjamin P. Kleinstiver, Sarah Tishkoff, Leonard I. Zon, Tamar Nijsten, Andrés Ruiz-Linares, David E. Fisher, Elisabeth Roider
Cell. Author manuscript; available in PMC 2022 Aug 5.
Published in final edited form as: Cell. 2021 Aug 5; 184(16): 4268–4283.e20. Published online 2021 Jul 6. doi: 10.1016/j.cell.2021.06.022
PMCID:
PMC8349839
AbstractArticlePDF–2.2M
13.
Loss of Nnt Increases Expression of Oxidative Phosphorylation Complexes in C57BL/6J Hearts
Jack L. Williams, Charlotte L. Hall, Eirini Meimaridou, Lou A. Metherell
Int J Mol Sci. 2021 Jun; 22(11): 6101. Published online 2021 Jun 5. doi: 10.3390/ijms22116101
PMCID:
PMC8201288
AbstractArticlePDF–2.6M
14.
Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer's disease
Kiran Chaudhari, Linshu Wang, Jonas Kruse, Winters Ali, Nathalie Sumien, Ritu Shetty, Jude Prah, Ran Liu, Jiong Shi, Michael Forster, Shao-Hua Yang
Neurol Res. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Neurol Res. 2021 Jul; 43(7): 570–581. Published online 2021 Mar 10. doi: 10.1080/01616412.2021.1893566
PMCID:
PMC8169538
AbstractArticlePDF–1.1M
15.
Asprosin-neutralizing antibodies as a treatment for metabolic syndrome
Ila Mishra, Clemens Duerrschmid, Zhiqiang Ku, Yang He, Wei Xie, Elizabeth Sabath Silva, Jennifer Hoffman, Wei Xin, Ningyan Zhang, Yong Xu, Zhiqiang An, Atul R Chopra
eLife. 2021; 10: e63784. Published online 2021 Apr 27. doi: 10.7554/eLife.63784
PMCID:
PMC8102062
AbstractArticlePDF–2.1M
16.
Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function
Nathan P. Ward, Yun Pyo Kang, Aimee Falzone, Theresa A. Boyle, Gina M. DeNicola
J Exp Med. 2020 Jun 1; 217(6): e20191689. Published online 2020 Mar 20. doi: 10.1084/jem.20191689
PMCID:
PMC7971138
AbstractArticlePDF–6.2M
17.
Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice
Marine L. Croze, Marcus F. Flisher, Arthur Guillaume, Caroline Tremblay, Glyn M. Noguchi, Sabrina Granziera, Kevin Vivot, Vincent C. Castillo, Scott A. Campbell, Julien Ghislain, Mark O. Huising, Vincent Poitout
Mol Metab. 2021 Mar; 45: 101166. Published online 2021 Jan 20. doi: 10.1016/j.molmet.2021.101166
PMCID:
PMC7873385
AbstractArticlePDF–3.9M
18.
Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure
Cody D. Smith, Cameron A. Schmidt, Chien-Te Lin, Kelsey H. Fisher-Wellman, P. Darrell Neufer
J Biol Chem. 2020 Nov 27; 295(48): 16207–16216. Published online 2020 Aug 3. doi: 10.1074/jbc.RA120.013899
PMCID:
PMC7705309
AbstractArticlePDF–1.0M
19.
Selective NADH communication from α-ketoglutarate dehydrogenase to mitochondrial transhydrogenase prevents reactive oxygen species formation under reducing conditions in the heart
Michael Wagner, Edoardo Bertero, Alexander Nickel, Michael Kohlhaas, Gary E. Gibson, Ward Heggermont, Stephane Heymans, Christoph Maack
Basic Res Cardiol. 2020; 115(5): 53. Published online 2020 Aug 3. doi: 10.1007/s00395-020-0815-1
PMCID:
PMC7399685
AbstractArticlePDF–2.4M
20.
Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not
Jack L Williams, Anju Paudyal, Sherine Awad, James Nicholson, Dominika Grzesik, Joaquin Botta, Eirini Meimaridou, Avinaash V Maharaj, Michelle Stewart, Andrew Tinker, Roger D Cox, Lou A Metherell
Life Sci Alliance. 2020 Apr; 3(4): e201900593. Published online 2020 Mar 25. doi: 10.26508/lsa.201900593
PMCID:
PMC7103425
AbstractArticlePDF–3.2M

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