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Select item 91308351.

Genome Replication Is Associated With Release of Immunogenic DNA Waste

Nadja Schubert, Tina Schumann, Elena Daum, Karolin Flade, Yan Ge, Lara Hagedorn, Winfried Edelmann, Luise Müller, Marc Schmitz, Gunnar Kuut, Veit Hornung, Rayk Behrendt, Axel Roers

Front Immunol. 2022; 13: 880413. Published online 2022 May 11. doi: 10.3389/fimmu.2022.880413

PMCID:: PMC9130835

Abstract Article PDF–6.8M

Select item 90044452.

Photorepair of Either CPD or 6-4PP DNA Lesions in Basal Keratinocytes Attenuates Ultraviolet-Induced Skin Effects in Nucleotide Excision Repair Deficient Mice

Gustavo S. Kajitani, Carolina Quayle, Camila C. M. Garcia, Wesley L. Fotoran, Juliana F. R. dos Santos, Gijsbertus T. J. van der Horst, Jan H. J. Hoeijmakers, Carlos F. M. Menck

Front Immunol. 2022; 13: 800606. Published online 2022 Mar 29. doi: 10.3389/fimmu.2022.800606

PMCID:: PMC9004445

Abstract Article PDF–2.2M

Select item 85443063.

Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model

Gustavo Satoru Kajitani, Lear Brace, Jose Humberto Trevino-Villarreal, Kaspar Trocha, Michael Robert MacArthur, Sarah Vose, Dorathy Vargas, Roderick Bronson, Sarah Jayne Mitchell, Carlos Frederico Martins Menck, James Robert Mitchell

Aging (Albany NY) 2021 Oct 15; 13(19): 22710–22731. Published online 2021 Oct 10. doi: 10.18632/aging.203617

PMCID:: PMC8544306

Abstract Article PDF–1.7M

Select item 71449634.

XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways

Lee Mulderrig, Juan I. Garaycoechea

PLoS Genet. 2020 Apr; 16(4): e1008555. Published online 2020 Apr 9. doi: 10.1371/journal.pgen.1008555

PMCID:: PMC7144963

Abstract Article PDF–3.1M

Select item 69611285.

Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts

Lisa Hölzl-Armstrong, Jill E. Kucab, Michael Korenjak, Mirjam Luijten, David H. Phillips, Jiri Zavadil, Volker M. Arlt

Methods Protoc. 2019 Dec; 2(4): 85. Published online 2019 Nov 13. doi: 10.3390/mps2040085

PMCID:: PMC6961128

Abstract Article PDF–16M

Select item 66756126.

DNA crosslink repair safeguards genomic stability during pre-meiotic germ cell development

Ross J Hill, Gerry P Crossan

Nat Genet. Author manuscript; available in PMC 2020 Jan 31.

Published in final edited form as: Nat Genet. 2019 Jul 4; 51(8): 1283–1294. Published online 2019 Jul 31. doi: 10.1038/s41588-019-0471-2

PMCID:: PMC6675612

Abstract Article PDF–3.5M

Select item 53010837.

Hearing Dysfunction in Xpa-Deficient Mice

Hitomi Shinomiya, Daisuke Yamashita, Takeshi Fujita, Eiji Nakano, Go Inokuchi, Shingo Hasegawa, Naoki Otsuki, Chikako Nishigori, Ken-ichi Nibu

Front Aging Neurosci. 2017; 9: 19. Published online 2017 Feb 10. doi: 10.3389/fnagi.2017.00019

PMCID:: PMC5301083

Abstract Article PDF–1.0M

Select item 47988488.

TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

Jill E. Kucab, Edwin P. Zwart, Harry van Steeg, Mirjam Luijten, Heinz H. Schmeiser, David H. Phillips, Volker M. Arlt

DNA Repair (Amst) 2016 Mar; 39: 21–33. doi: 10.1016/j.dnarep.2015.11.004

PMCID:: PMC4798848

Abstract Article PDF–1.4M

Select item 46258379.

Defective Mitophagy in XPA via PARP1 Hyperactivation and NAD+/SIRT1 Reduction

Evandro Fei Fang, Morten Scheibye-Knudsen, Lear E. Brace, Henok Kassahun, Tanima SenGupta, Hilde Nilsen, James R. Mitchell, Deborah L. Croteau, Vilhelm A. Bohr

Cell. Author manuscript; available in PMC 2015 Oct 29.

Published in final edited form as: Cell. 2014 May 8; 157(4): 882–896. doi: 10.1016/j.cell.2014.03.026

PMCID:: PMC4625837

Abstract Article PDF–3.0M

Select item 458728610.

Spatiotemporal regulation of GLI target genes in the mammalian limb bud

Jordan P. Lewandowski, Fang Du, Shilu Zhang, Marian B. Powell, Kristin N. Falkenstein, Hongkai Ji, Steven A. Vokes

Dev Biol. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Dev Biol. 2015 Oct 1; 406(1): 92–103. Published online 2015 Jul 31. doi: 10.1016/j.ydbio.2015.07.022

PMCID:: PMC4587286

Abstract Article PDF–2.0M

Select item 455148011.

Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice

Hironobu Nakane, Seiichi Hirota, Philip J. Brooks, Yusaku Nakabeppu, Yoshimichi Nakatsu, Yoshitake Nishimune, Akihiro Iino, Kiyoji Tanaka

DNA Repair (Amst) Author manuscript; available in PMC 2015 Aug 27.

Published in final edited form as: DNA Repair (Amst). 2008 Dec 1; 7(12): 1938–1950. Published online 2008 Oct 1. doi: 10.1016/j.dnarep.2008.08.003

PMCID:: PMC4551480

Abstract Article PDF–1.5M

Select item 429538512.

The RASSF1A Tumor Suppressor Regulates XPA-Mediated DNA Repair

Howard Donninger, Jennifer Clark, Francesca Rinaldo, Nicholas Nelson, Thibaut Barnoud, M. Lee Schmidt, Katharine R. Hobbing, Michele D. Vos, Brian Sils, Geoffrey J. Clark

Mol Cell Biol. 2015 Jan; 35(1): 277–287. Prepublished online 2014 Nov 3. Published online 2014 Dec 9. doi: 10.1128/MCB.00202-14

PMCID:: PMC4295385

Abstract Article PDF–1.9M

Select item 386371513.

Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway

Petra Hajkova, Sean J. Jeffries, Caroline Lee, Nigel Miller, Stephen P. Jackson, M. Azim Surani

Science. Author manuscript; available in PMC 2013 Dec 16.

Published in final edited form as: Science. 2010 Jul 2; 329(5987): 10.1126/science.1187945. doi: 10.1126/science.1187945

PMCID:: PMC3863715

Abstract Article PDF–2.1M

Select item 379943714.

XPD-dependent activation of apoptosis in response to triplex-induced DNA damage

Meetu Kaushik Tiwari, Faye A. Rogers

Nucleic Acids Res. 2013 Oct; 41(19): 8979–8994. Published online 2013 Aug 2. doi: 10.1093/nar/gkt670

PMCID:: PMC3799437

Abstract Article PDF–17M

Select item 360416615.

Silymarin inhibits ultraviolet radiation-induced immune suppression through DNA repair-dependent activation of dendritic cells and stimulation of effector T cells

Mudit Vaid, Ram Prasad, Tripti Singh, Craig A. Elmets, Hui Xu, Santosh K. Katiyar

Biochem Pharmacol. Author manuscript; available in PMC 2014 Apr 15.

Published in final edited form as: Biochem Pharmacol. 2013 Apr 15; 85(8): 1066–1076. Published online 2013 Feb 5. doi: 10.1016/j.bcp.2013.01.026

PMCID:: PMC3604166

Abstract Article PDF–2.6M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 349904517.

Benzo[a]pyrene (BP) DNA adduct formation in DNA repair–deficient p53 haploinsufficient [Xpa(−/−)p53(+/−)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days

Kaarthik John, M.Margaret Pratt, Frederick A. Beland, Mona I. Churchwell, Gail McMullen, Ofelia A. Olivero, Igor P. Pogribny, Miriam C. Poirier

Carcinogenesis. 2012 Nov; 33(11): 2236–2241. Published online 2012 Jul 14. doi: 10.1093/carcin/bgs247

PMCID:: PMC3499045

Abstract Article PDF–455K

Select item 342454418.

Endogenous formation and repair of oxidatively induced G[8-5 m]T intrastrand cross-link lesion

Jin Wang, Huachuan Cao, Changjun You, Bifeng Yuan, Ralf Bahde, Sanjeev Gupta, Chikako Nishigori, Laura J. Niedernhofer, Philip J. Brooks, Yinsheng Wang

Nucleic Acids Res. 2012 Aug; 40(15): 7368–7374. Published online 2012 May 11. doi: 10.1093/nar/gks357