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Select item 103421411.

GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer

Kelsey E. Huntington, Anna D. Louie, Praveen R. Srinivasan, Christoph Schorl, Shaolei Lu, David Silverberg, Daniel Newhouse, Zhijin Wu, Lanlan Zhou, Brittany A. Borden, Francis J. Giles, Mark Dooner, Benedito A. Carneiro, Wafik S. El-Deiry

Int J Mol Sci. 2023 Jul; 24(13): 10870. Published online 2023 Jun 29. doi: 10.3390/ijms241310870

PMCID:: PMC10342141

Abstract Article PDF–5.4M

Select item 95467742.

Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p to induce M2 macrophage polarization and promote glioma progression

Ming Li, Hao Xu, Yanhua Qi, Ziwen Pan, Boyan Li, Zijie Gao, Rongrong Zhao, Hao Xue, Gang Li

Oncogene. 2022; 41(41): 4618–4632. Published online 2022 Sep 9. doi: 10.1038/s41388-022-02457-w

PMCID:: PMC9546774

Abstract Article PDF–12M

Select item 72017443.

CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers

Nour K. Majbour, Jan O. Aasly, Eldbjørg Hustad, Mercy A. Thomas, Nishant N. Vaikath, Naser Elkum, Wilma D. J. van de Berg, Takahiko Tokuda, Brit Mollenhauer, Henk W. Berendse, Omar M. A. El-Agnaf

Transl Neurodegener. 2020; 9: 15. Published online 2020 May 6. doi: 10.1186/s40035-020-00192-4

PMCID:: PMC7201744

Abstract Article PDF–1.0M

Select item 67006394.

What Have We Learned from Cerebrospinal Fluid Studies about Biomarkers for Detecting LRRK2 Parkinson’s Disease Patients and Healthy Subjects with Parkinson’s-Associated LRRK2 Mutations?

David A. Loeffler, Jan O. Aasly, Peter A. LeWitt, Mary P. Coffey

J Parkinsons Dis. 2019; 9(3): 467–488. Prepublished online 2019 Jul 12. Published online 2019 Jul 30. doi: 10.3233/JPD-191630

PMCID:: PMC6700639

Abstract Article PDF–150K

Select item 57006795.

Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers

Shijie Wang, Zhiyong Liu, Tao Ye, Omar S. Mabrouk, Tyler Maltbie, Jan Aasly, Andrew B. West

Acta Neuropathol Commun. 2017; 5: 86. Published online 2017 Nov 22. doi: 10.1186/s40478-017-0492-y

PMCID:: PMC5700679

Abstract Article PDF–1.6M

Select item 38364786.

LRRK2 secretion in exosomes is regulated by 14-3-3

Kyle B. Fraser, Mark S. Moehle, João P.L. Daher, Philip J. Webber, Jeri Y. Williams, Carrie A. Stewart, Talene A. Yacoubian, Rita M. Cowell, Terje Dokland, Tong Ye, Dongquan Chen, Gene P. Siegal, Robert A. Galemmo, Elpida Tsika, Darren J. Moore, David G. Standaert, Kyoko Kojima, James A. Mobley, Andrew B. West

Hum Mol Genet. 2013 Dec 15; 22(24): 4988–5000. Published online 2013 Jul 25. doi: 10.1093/hmg/ddt346

PMCID:: PMC3836478

Abstract Article PDF–1.4M

Select item 31307167.

Effect of a structurally modified human granulocyte colony stimulating factor, G-CSFa, on leukopenia in mice and monkeys

Yongping Jiang, Wenhong Jiang, Yuchang Qiu, Wei Dai

J Hematol Oncol. 2011; 4: 28. Published online 2011 Jun 13. doi: 10.1186/1756-8722-4-28

PMCID:: PMC3130716

Abstract Article PDF–1.7M

Select item 62992238.

Transcriptional Profiling of Patient Isolates Identifies a Novel TOR/Starvation Regulatory Pathway in Cryptococcal Virulence

Yoon-Dong Park, Joseph N. Jarvis, Guowu Hu, Sarah E. Davis, Jin Qiu, Nannan Zhang, Christopher Hollingsworth, Angela Loyse, Paul J. Gardina, Tibor Valyi-Nagy, Timothy G. Myers, Thomas S. Harrison, Tihana Bicanic, Peter R. Williamson

mBio. 2018 Nov-Dec; 9(6): e02353-18. Published online 2018 Dec 18. doi: 10.1128/mBio.02353-18