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Items: 20

Select item 97924611.

GTS-21, a selective alpha7 nicotinic acetylcholine receptor agonist, ameliorates diabetic nephropathy in Lepr^db/db mice

Qinghe Meng, Xinghan Tian, Junwei Li, Napat Pruekprasert, Ravi Dhawan, George G. Holz, Robert N. Cooney

Sci Rep. 2022; 12: 22360. Published online 2022 Dec 26. doi: 10.1038/s41598-022-27015-y

PMCID:: PMC9792461

Article PDF–2.3M

Select item 93883412.

Tensin 2-deficient nephropathy: mechanosensitive nephropathy, genetic susceptibility

Hayato Sasaki, Nobuya Sasaki

Exp Anim. 2022; 71(3): 252–263. Published online 2022 Apr 19. doi: 10.1538/expanim.22-0031

PMCID:: PMC9388341

Article PDF–2.6M

Select item 93787233.

Glomerular basement membrane deposition of collagen α1(III) in Alport glomeruli by mesangial filopodia injures podocytes via aberrant signaling through DDR1 and integrin α2β1

Jacob Madison, Kevin Wilhelm, Daniel T Meehan, Duane Delimont, Gina Samuelson, Dominic Cosgrove

J Pathol. 2022 Sep; 258(1): 26–37. Published online 2022 Jun 22. doi: 10.1002/path.5969

PMCID:: PMC9378723

Article PDF–13M

Select item 88925004.

Single-Cell Transcriptomics Reveal Disrupted Kidney Filter Cell-Cell Interactions after Early and Selective Podocyte Injury

Abbe R. Clark, Jamie Marshall, Yiming Zhou, Monica S. Montesinos, Haiqi Chen, Lan Nguyen, Fei Chen, Anna Greka

Am J Pathol. 2022 Feb; 192(2): 281–294. doi: 10.1016/j.ajpath.2021.11.004

PMCID:: PMC8892500

Article PDF–15M

Select item 84747095.

LAMA2 and LOXL4 are candidate FSGS genes

Poornima Vijayan, Saidah Hack, Tony Yao, Mohammad Azfar Qureshi, Andrew D. Paterson, Rohan John, Bernard Davenport, Rachel Lennon, York Pei, Moumita Barua

BMC Nephrol. 2021; 22: 320. Published online 2021 Sep 26. doi: 10.1186/s12882-021-02524-6

PMCID:: PMC8474709

Article PDF–1.1M

Select item 84644236.

PP2 Ameliorates Renal Fibrosis by Regulating the NF-κB/COX-2 and PPARγ/UCP2 Pathway in Diabetic Mice

Jinying Wei, Xinna Deng, Yang Li, Runmei Li, Zhaohua Yang, Xiuyuan Li, Shan Song, Yonghong Shi, Huijun Duan, Haijiang Wu

Oxid Med Cell Longev. 2021; 2021: 7394344. Published online 2021 Sep 17. doi: 10.1155/2021/7394344

PMCID:: PMC8464423

Article PDF–7.1M

Select item 49940047.

Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions

Xiaoxia Wang, E. Shen, Yanzhe Wang, Junhui Li, Dongsheng Cheng, Yuqiang Chen, Dingkun Gui, Niansong Wang

Sci Rep. 2016; 6: 31506. Published online 2016 Aug 23. doi: 10.1038/srep31506

PMCID:: PMC4994004

Article PDF–2.1M

Select item 49469728.

Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease

Brianna Dufek, Daniel Meehan, Duane Delimont, Linda Cheung, Michael Anne Gratton, Grady Phillips, Wenping Song, Shiguang Liu, Dominic Cosgrove

Kidney Int. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Kidney Int. 2016 Aug; 90(2): 300–310. Published online 2016 Apr 27. doi: 10.1016/j.kint.2016.02.018

PMCID:: PMC4946972

Article PDF–1.6M

Select item 47691769.

Lipoprotein X Causes Renal Disease in LCAT Deficiency

Alice Ossoli, Edward B. Neufeld, Seth G. Thacker, Boris Vaisman, Milton Pryor, Lita A. Freeman, Christine A. Brantner, Irina Baranova, Nicolás O. Francone, Stephen J. Demosky, Jr., Cecilia Vitali, Monica Locatelli, Mauro Abbate, Carlamaria Zoja, Guido Franceschini, Laura Calabresi, Alan T. Remaley

PLoS One. 2016; 11(2): e0150083. Published online 2016 Feb 26. doi: 10.1371/journal.pone.0150083

PMCID:: PMC4769176

Article PDF–2.1M

Select item 415087010.

Nephron-deficient Fvb mice develop rapidly progressive renal failure and heavy albuminuria involving excess glomerular GLUT1 and VEGF

Youli Wang, Kathleen O Heilig, Andrew W Minto, Shenglin Chen, Minghui Xiang, David A Dean, Richard C Geiger, Anthony Chang, Dimitrina D Pravtcheva, Martin Schlimme, Dilip K Deb, Ying Wang, Charles W Heilig

Lab Invest. Author manuscript; available in PMC 2014 Sep 2.

Published in final edited form as: Lab Invest. 2010 Jan; 90(1): 83–97. Published online 2009 Nov 16. doi: 10.1038/labinvest.2009.95

PMCID:: PMC4150870

Article PDF–3.8M

Select item 325826411.

Glycoprotein Hyposialylation Gives Rise to a Nephrotic-Like Syndrome That Is Prevented by Sialic Acid Administration in GNE V572L Point-Mutant Mice

Mitutoshi Ito, Kazushi Sugihara, Tomoya Asaka, Tadashi Toyama, Toru Yoshihara, Kengo Furuichi, Takashi Wada, Masahide Asano

PLoS One. 2012; 7(1): e29873. Published online 2012 Jan 13. doi: 10.1371/journal.pone.0029873

PMCID:: PMC3258264

Article PDF–4.4M

Select item 320363012.

IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cells

Jan Novak, Leona Raskova Kafkova, Hitoshi Suzuki, Milan Tomana, Karel Matousovic, Rhubell Brown, Stacy Hall, John T. Sanders, T. Matthew Eison, Zina Moldoveanu, Lea Novak, Zdenek Novak, Richard Mayne, Bruce A. Julian, Jiri Mestecky, Robert J. Wyatt

Nephrol Dial Transplant. 2011 Nov; 26(11): 3451–3457. Published online 2011 Aug 9. doi: 10.1093/ndt/gfr448

PMCID:: PMC3203630

Article PDF–282K

Select item 288859613.

Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy

Ting-Chi Lu, Zhao-Hui Wang, Xiaobei Feng, Peter Y. Chuang, Wei Fang, Yuhong Shen, David E. Levy, Huabao Xiong, Nan Chen, John Cijiang He

Kidney Int. Author manuscript; available in PMC 2010 Jun 21.

Published in final edited form as: Kidney Int. 2009 Jul; 76(1): 63–71. Published online 2009 Apr 8. doi: 10.1038/ki.2009.98

PMCID:: PMC2888596

Article PDF–2.6M

Select item 280808914.

Laminin α4-Null Mutant Mice Develop Chronic Kidney Disease with Persistent Overexpression of Platelet-Derived Growth Factor

Christine K. Abrass, Kim M. Hansen, Bruce L. Patton

Am J Pathol. 2010 Feb; 176(2): 839–849. doi: 10.2353/ajpath.2010.090570

PMCID:: PMC2808089

Article PDF–1.8M

Select item 273978415.

Impact of obesity on renal structure and function in the presence and absence of hypertension: evidence from melanocortin-4 receptor-deficient mice

Jussara M. do Carmo, Lakshmi S. Tallam, John V. Roberts, Elizabeth L. Brandon, John Biglane, Alexandre A. da Silva, John E. Hall

Am J Physiol Regul Integr Comp Physiol. 2009 Sep; 297(3): R803–R812. Published online 2009 Jul 15. doi: 10.1152/ajpregu.00187.2009

PMCID:: PMC2739784

Article

Select item 225824716.

Integrin α1β1 Regulates Matrix Metalloproteinases via P38 Mitogen-Activated Protein Kinase in Mesangial Cells : Implications for Alport Syndrome

Dominic Cosgrove, Daniel T. Meehan, Duane Delimont, Ambra Pozzi, Xiwu Chen, Kathyrn D. Rodgers, Richard M. Tempero, Marisa Zallocchi, Velidi H. Rao

Am J Pathol. 2008 Mar; 172(3): 761–773. doi: 10.2353/ajpath.2008.070473

PMCID:: PMC2258247

Article PDF–1.4M

Select item 188571817.

Integrin α1β1 and Transforming Growth Factor-β1 Play Distinct Roles in Alport Glomerular Pathogenesis and Serve as Dual Targets for Metabolic Therapy

Dominic Cosgrove, Kathryn Rodgers, Daniel Meehan, Caroline Miller, Karen Bovard, Amy Gilroy, Humphrey Gardner, Victor Kotelianski, Phillip Gotwals, Aldo Amatucci, Raghu Kalluri

Am J Pathol. 2000 Nov; 157(5): 1649–1659. doi: 10.1016/s0002-9440(10)64802-x

PMCID:: PMC1885718

Article PDF–1.9M

Select item 185187118.

Development of Immunoglobulin A Nephropathy- Like Disease in β-1,4-Galactosyltransferase-I-Deficient Mice

Toshikazu Nishie, Osamu Miyaishi, Haruhito Azuma, Akihiko Kameyama, Chie Naruse, Noriyoshi Hashimoto, Hitoshi Yokoyama, Hisashi Narimatsu, Takashi Wada, Masahide Asano

Am J Pathol. 2007 Feb; 170(2): 447–456. doi: 10.2353/ajpath.2007.060559

PMCID:: PMC1851871

Article PDF–893K

Select item 185088019.

Mylène Potier, Michael Karl, Feng Zheng, Sharon J. Elliot, Gary E. Striker, Liliane J. Striker

Am J Pathol. 2002 May; 160(5): 1877–1885. doi: 10.1016/S0002-9440(10)61134-0

PMCID:: PMC1850880

Article PDF–210K

Select item 140972420.

Large-scale identification of genes implicated in kidney glomerulus development and function

Minoru Takemoto, Liqun He, Jenny Norlin, Jaakko Patrakka, Zhijie Xiao, Tatiana Petrova, Cecilia Bondjers, Julia Asp, Elisabet Wallgard, Ying Sun, Tore Samuelsson, Petter Mostad, Samuel Lundin, Naoyuki Miura, Yoshikazu Sado, Kari Alitalo, Susan E Quaggin, Karl Tryggvason, Christer Betsholtz

EMBO J. 2006 Mar 8; 25(5): 1160–1174. Published online 2006 Feb 23. doi: 10.1038/sj.emboj.7601014